STRINGSTRING
SYT8 SYT8 LOC103077548 LOC103077548 IL7R IL7R EPS15 EPS15 LDLRAP1 LDLRAP1 HBEGF HBEGF NECAP2 NECAP2 KXD1 KXD1 ZFYVE1 ZFYVE1 FCHO1 FCHO1 EPS15L1 EPS15L1 STAM STAM NETO1 NETO1 AP2S1 AP2S1 SH3GL1 SH3GL1 SYT11 SYT11 DVL2 DVL2 IGF2R IGF2R ARRB2 ARRB2 TF TF LOC103090671 LOC103090671 CD3G CD3G CLTA CLTA WNT5A WNT5A LOC103069935 LOC103069935 UBQLN4 UBQLN4 VAMP2 VAMP2 LOC103077264 LOC103077264 SYT2 SYT2 FCHO2 FCHO2 COPS2 COPS2 ITSN2 ITSN2 GRB2 GRB2 LOC103072950 LOC103072950 AVPR2 AVPR2 ARRB1 ARRB1 CD3D CD3D REPS2 REPS2 CBL CBL KIAA0319 KIAA0319 SCARB2 SCARB2 TGFA TGFA AAK1 AAK1 VAMP3 VAMP3 COPS8 COPS8 ENTHD1 ENTHD1 GPR52 GPR52 KIAA0319L KIAA0319L LOC103076438 LOC103076438 LOC103078080 LOC103078080 TACR1 TACR1 ADRBK1 ADRBK1 NETO2 NETO2 SYT1 SYT1 LRP2 LRP2 CLTC CLTC PICALM PICALM LOC103083100 LOC103083100 UBC UBC LOC103083372 LOC103083372 PPP1R42 PPP1R42 EPN2 EPN2 CFTR CFTR SYT4 SYT4 NEDD8 NEDD8 LOC103088327 LOC103088327 LOC103070590 LOC103070590 COPS5 COPS5 AP2B1 AP2B1 FZD4 FZD4 UBL7 UBL7 COPS4 COPS4 SNAP91 SNAP91 ADRB2 ADRB2 COPS3 COPS3 SLC18A3 SLC18A3 BMP2K BMP2K VAMP4 VAMP4 AGTR1 AGTR1 TOR1A TOR1A TOR1B TOR1B SLC2A8 SLC2A8 SGIP1 SGIP1 DAB2 DAB2 ZFYVE19 ZFYVE19 UBB UBB LDLR LDLR LOC103069110 LOC103069110 CLTB CLTB UBA52 UBA52 AREG AREG ADRBK2 ADRBK2 EREG EREG EGFR EGFR LMBRD2 LMBRD2 HGS HGS BTC BTC EPGN EPGN AP2A1 AP2A1 LOC103088397 LOC103088397 MCTP2 MCTP2 APOB APOB COPS7B COPS7B CLPB CLPB EPN3 EPN3 EGF EGF STAM2 STAM2 AVP AVP RPS27A RPS27A AP2A2 AP2A2 SH3GL2 SH3GL2 CLHC1 CLHC1 CHRM2 CHRM2 TFRC TFRC AGFG1 AGFG1 EPN1 EPN1 AP2M1 AP2M1 VAMP5 VAMP5 LOC103076597 LOC103076597 REPS1 REPS1 UBQLN1 UBQLN1 M6PR M6PR CD4 CD4 ADRB1 ADRB1 UBQLN2 UBQLN2 ITSN1 ITSN1 GPR21 GPR21 AGFG2 AGFG2 COPS6 COPS6 SH3KBP1 SH3KBP1 NECAP1 NECAP1 COPS7A COPS7A VAMP8 VAMP8 ARR3 ARR3 MCTP1 MCTP1 SH3GL3 SH3GL3 STON2 STON2 LOC103070273 LOC103070273 GPS1 GPS1 SYT9 SYT9 STON1 STON1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYT8Synaptotagmin-8. (360 aa)
LOC103077548LOW QUALITY PROTEIN: ubiquilin-3-like. (602 aa)
IL7RInterleukin-7 receptor subunit alpha. (459 aa)
EPS15Epidermal growth factor receptor substrate 15. (902 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1. (309 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
NECAP2Adaptin ear-binding coat-associated protein 2 isoform X1. (274 aa)
KXD1kxDL motif-containing protein 1. (176 aa)
ZFYVE1Zinc finger FYVE domain-containing protein 1 isoform X1. (787 aa)
FCHO1FCH domain only protein 1 isoform X3. (889 aa)
EPS15L1Epidermal growth factor receptor substrate 15-like 1. (864 aa)
STAMSignal transducing adapter molecule 1. (507 aa)
NETO1Neuropilin and tolloid-like protein 1 isoform X1. (532 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
SH3GL1endophilin-A2 isoform X1. (369 aa)
SYT11Synaptotagmin-11. (428 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (734 aa)
IGF2RCation-independent mannose-6-phosphate receptor. (2490 aa)
ARRB2Beta-arrestin-2 isoform X1. (421 aa)
TFSerotransferrin; Belongs to the transferrin family. (709 aa)
LOC103090671Inhibitor of carbonic anhydrase-like isoform X1; Belongs to the transferrin family. (702 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (182 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (243 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LOC103069935Chaperone protein ClpB2, chloroplastic-like; Belongs to the ClpA/ClpB family. (701 aa)
UBQLN4Ubiquilin-4. (583 aa)
VAMP2Vesicle-associated membrane protein 2. (116 aa)
LOC103077264BMP-2-inducible protein kinase-like. (291 aa)
SYT2Synaptotagmin-2 isoform X1. (422 aa)
FCHO2FCH domain only protein 2. (835 aa)
COPS2COP9 signalosome complex subunit 2 isoform X1. (450 aa)
ITSN2LOW QUALITY PROTEIN: intersectin-2. (1697 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
LOC103072950Uncharacterized protein LOC103072950. (442 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
ARRB1Beta-arrestin-1. (418 aa)
CD3DT-cell surface glycoprotein CD3 delta chain isoform X1. (171 aa)
REPS2ralBP1-associated Eps domain-containing protein 2 isoform X2. (648 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
KIAA0319Dyslexia-associated protein KIAA0319 homolog isoform X2. (1083 aa)
SCARB2Lysosome membrane protein 2 isoform X1; Belongs to the CD36 family. (478 aa)
TGFAProtransforming growth factor alpha. (145 aa)
AAK1AP2-associated protein kinase 1. (957 aa)
VAMP3Vesicle-associated membrane protein 3. (104 aa)
COPS8COP9 signalosome complex subunit 8. (209 aa)
ENTHD1ENTH domain-containing protein 1. (610 aa)
GPR52Probable G-protein coupled receptor 52; Belongs to the G-protein coupled receptor 1 family. (361 aa)
KIAA0319LDyslexia-associated protein KIAA0319-like protein homolog. (1044 aa)
LOC103076438ubiquitin-40S ribosomal protein S27a-like. (155 aa)
LOC103078080Uncharacterized protein FLJ45252-like. (406 aa)
TACR1substance-P receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
ADRBK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (692 aa)
NETO2Neuropilin and tolloid-like protein 2. (518 aa)
SYT1Synaptotagmin-1 isoform X1. (422 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4672 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1818 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein isoform X1. (652 aa)
LOC103083100ubiquitin-60S ribosomal protein L40-like. (116 aa)
UBCpolyubiquitin-C. (462 aa)
LOC103083372AP-2 complex subunit beta-like. (263 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (357 aa)
EPN2Epsin-2 isoform X1. (643 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
SYT4Synaptotagmin-4-like isoform X1. (425 aa)
NEDD8NEDD8. (81 aa)
LOC103088327Heat shock protein 78, mitochondrial-like; Belongs to the ClpA/ClpB family. (756 aa)
LOC103070590AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (598 aa)
COPS5COP9 signalosome complex subunit 5. (334 aa)
AP2B1AP-1 complex subunit beta-1 isoform X1. (304 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
UBL7Ubiquitin-like protein 7 isoform X1. (380 aa)
COPS4COP9 signalosome complex subunit 4 isoform X1. (406 aa)
SNAP91Clathrin coat assembly protein AP180 isoform X1. (907 aa)
ADRB2Beta-2 adrenergic receptor. (419 aa)
COPS3COP9 signalosome complex subunit 3. (423 aa)
SLC18A3Vesicular acetylcholine transporter. (499 aa)
BMP2KBMP-2-inducible protein kinase. (718 aa)
VAMP4Vesicle-associated membrane protein 4 isoform X1. (141 aa)
AGTR1Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
TOR1ALOW QUALITY PROTEIN: torsin-1A. (419 aa)
TOR1BTorsin. (335 aa)
SLC2A8Solute carrier family 2, facilitated glucose transporter member 8 isoform X2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (479 aa)
SGIP1SH3-containing GRB2-like protein 3-interacting protein 1 isoform X1. (825 aa)
DAB2Disabled homolog 2. (769 aa)
ZFYVE19Zinc finger FYVE domain-containing protein 19. (398 aa)
UBBpolyubiquitin-C isoform X1. (305 aa)
LDLRLow-density lipoprotein receptor. (857 aa)
LOC103069110Uncharacterized protein LOC103069110. (1113 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
AREGAmphiregulin isoform X1. (254 aa)
ADRBK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
EREGProepiregulin. (163 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
LMBRD2LMBR1 domain-containing protein 2. (695 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
BTCProbetacellulin. (178 aa)
EPGNEpigen isoform X1. (153 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa)
LOC103088397Vesicle-associated membrane protein 7-like isoform X1; Belongs to the synaptobrevin family. (220 aa)
MCTP2Multiple C2 and transmembrane domain-containing protein 2-like. (861 aa)
APOBLOW QUALITY PROTEIN: apolipoprotein B-100. (4572 aa)
COPS7BCOP9 signalosome complex subunit 7b isoform X1. (264 aa)
CLPBCaseinolytic peptidase B protein homolog isoform X1. (707 aa)
EPN3Epsin-3. (604 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
STAM2Signal transducing adapter molecule 2 isoform X1. (526 aa)
AVPVasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family. (166 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (938 aa)
SH3GL2endophilin-A1. (352 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (585 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
TFRCTransferrin receptor protein 1 isoform X2. (770 aa)
AGFG1arf-GAP domain and FG repeat-containing protein 1 isoform X1. (584 aa)
EPN1Epsin-1 isoform X1. (576 aa)
AP2M1AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
VAMP5Vesicle-associated membrane protein 5. (111 aa)
LOC103076597ubiquitin-40S ribosomal protein S27a-like. (187 aa)
REPS1ralBP1-associated Eps domain-containing protein 1 isoform X1. (796 aa)
UBQLN1Ubiquilin-1 isoform X1. (590 aa)
M6PRCation-dependent mannose-6-phosphate receptor isoform X1. (278 aa)
CD4T-cell surface glycoprotein CD4. (454 aa)
ADRB1Beta-1 adrenergic receptor. (465 aa)
UBQLN2Ubiquilin-2-like isoform X1. (624 aa)
ITSN1Intersectin-1-like. (616 aa)
GPR21Probable G-protein coupled receptor 21; Belongs to the G-protein coupled receptor 1 family. (349 aa)
AGFG2arf-GAP domain and FG repeat-containing protein 2. (479 aa)
COPS6COP9 signalosome complex subunit 6. (326 aa)
SH3KBP1SH3 domain-containing kinase-binding protein 1 isoform X1. (665 aa)
NECAP1Adaptin ear-binding coat-associated protein 1. (275 aa)
COPS7ACOP9 signalosome complex subunit 7a isoform X1. (275 aa)
VAMP8Vesicle-associated membrane protein 8. (99 aa)
ARR3LOW QUALITY PROTEIN: arrestin-C. (393 aa)
MCTP1Multiple C2 and transmembrane domain-containing protein 1 isoform X1. (999 aa)
SH3GL3endophilin-A3. (347 aa)
STON2Stonin-2; Belongs to the Stoned B family. (897 aa)
LOC103070273Chaperone protein ClpB2, chloroplastic-like; Belongs to the ClpA/ClpB family. (854 aa)
GPS1COP9 signalosome complex subunit 1 isoform X1. (527 aa)
SYT9Synaptotagmin-9. (589 aa)
STON1Stonin-1; Belongs to the Stoned B family. (730 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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