STRINGSTRING
UHMK1 UHMK1 KRAS KRAS SRC SRC S1PR3 S1PR3 FOXO3 FOXO3 GNG2 GNG2 CAV2 CAV2 PRKCZ PRKCZ ERAS ERAS MAPK1 MAPK1 GNB1 GNB1 GNAI3 GNAI3 GNG10 GNG10 GNG11 GNG11 PIK3R3 PIK3R3 ELK1 ELK1 CAV1 CAV1 STRN3 STRN3 GNG4 GNG4 SPHK1 SPHK1 TGFA TGFA PDPK1 PDPK1 GNG13 GNG13 PIK3R1 PIK3R1 SHC1 SHC1 ESR1 ESR1 GNG8 GNG8 STRN4 STRN4 CALM3 CALM3 ESR2 ESR2 GNB5 GNB5 PIK3R2 PIK3R2 CSDE1 CSDE1 PRMT1 PRMT1 GNG3 GNG3 NOS3 NOS3 CALM1 CALM1 EPGN EPGN NRAS NRAS WDR64 WDR64 EGF EGF PTK2 PTK2 LOC103081266 LOC103081266 LOC103075492 LOC103075492 GNAT3 GNAT3 PIK3CA PIK3CA LOC103089724 LOC103089724 GNAI1 GNAI1 LOC103074541 LOC103074541 XPO1 XPO1 HRAS HRAS GNAI2 GNAI2 LOC103069500 LOC103069500 STRN STRN GNB2 GNB2 GNB4 GNB4 GNB3 GNB3 IGF1R IGF1R ZDHHC7 ZDHHC7 HSPB1 HSPB1 PRMT8 PRMT8 CDKN1B CDKN1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UHMK1Serine/threonine-protein kinase Kist isoform X1. (424 aa)
KRASGTPase KRas. (188 aa)
SRCTyrosine-protein kinase. (548 aa)
S1PR3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
FOXO3Forkhead box protein O3. (672 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
ERASGTPase ERas. (233 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1. (340 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (444 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
STRN3Striatin-3 isoform X1. (796 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
SPHK1Sphingosine kinase 1. (484 aa)
TGFAProtransforming growth factor alpha. (145 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (80 aa)
STRN4Striatin-4 isoform X1. (766 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
ESR2Estrogen receptor beta. (533 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (395 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (843 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
EPGNEpigen isoform X1. (153 aa)
NRASGTPase NRas. (189 aa)
WDR64WD repeat-containing protein 64. (1080 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1003 aa)
LOC103081266Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
LOC103075492Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNAT3LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(T) subunit alpha-3. (320 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
LOC103089724Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
LOC103074541LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
XPO1Exportin-1. (1071 aa)
HRASGTPase HRas isoform X1. (189 aa)
GNAI2LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I) subunit alpha-2. (360 aa)
LOC103069500Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
STRNStriatin isoform X1. (780 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (308 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (201 aa)
PRMT8Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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