STRINGSTRING
PIK3R1 PIK3R1 KRAS KRAS SYK SYK SOS1 SOS1 FOXO3 FOXO3 GRB10 GRB10 CSK CSK SLA2 SLA2 SLA SLA ERAS ERAS ABL2 ABL2 UBC UBC LOC103083100 LOC103083100 LOC103076438 LOC103076438 PTPRJ PTPRJ CBL CBL GRAP2 GRAP2 LOC103072950 LOC103072950 GRB2 GRB2 GAB2 GAB2 CSDE1 CSDE1 UBB UBB UBA52 UBA52 SOCS6 SOCS6 NRAS NRAS FLT3LG FLT3LG RPS27A RPS27A GAB1 GAB1 SH2B3 SH2B3 PIK3CA PIK3CA HRAS HRAS LOC103076597 LOC103076597 SOCS2 SOCS2 LCK LCK CDKN1B CDKN1B FLT3 FLT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
KRASGTPase KRas. (188 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
FOXO3Forkhead box protein O3. (672 aa)
GRB10Growth factor receptor-bound protein 10 isoform X1. (588 aa)
CSKTyrosine-protein kinase. (450 aa)
SLA2Src-like-adapter 2. (276 aa)
SLASrc-like-adapter isoform X1. (276 aa)
ERASGTPase ERas. (233 aa)
ABL2Tyrosine-protein kinase. (1067 aa)
UBCpolyubiquitin-C. (462 aa)
LOC103083100ubiquitin-60S ribosomal protein L40-like. (116 aa)
LOC103076438ubiquitin-40S ribosomal protein S27a-like. (155 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta-like. (1155 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
GRAP2GRB2-related adapter protein 2. (317 aa)
LOC103072950Uncharacterized protein LOC103072950. (442 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
GAB2GRB2-associated-binding protein 2. (640 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (843 aa)
UBBpolyubiquitin-C isoform X1. (305 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
NRASGTPase NRas. (189 aa)
FLT3LGFms-related tyrosine kinase 3 ligand isoform X1. (296 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (723 aa)
SH2B3SH2B adapter protein 3. (573 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
HRASGTPase HRas isoform X1. (189 aa)
LOC103076597ubiquitin-40S ribosomal protein S27a-like. (187 aa)
SOCS2Suppressor of cytokine signaling 2 isoform X1. (198 aa)
LCKTyrosine-protein kinase. (520 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.