STRINGSTRING
UGT1A10 UGT1A10 NME6 NME6 DPYS DPYS UPP2 UPP2 MGST2 MGST2 LOC103079434 LOC103079434 LOC103071327 LOC103071327 IMPDH2 IMPDH2 GSTM3 GSTM3 LOC103072071 LOC103072071 MPO MPO LOC103082472 LOC103082472 LOC103078149 LOC103078149 LOC103081925 LOC103081925 GSTA4 GSTA4 LOC103078627 LOC103078627 UMPS UMPS LOC103070610 LOC103070610 LOC103079831 LOC103079831 UPP1 UPP1 LOC103082194 LOC103082194 GUSB GUSB UPB1 UPB1 GSTA2 GSTA2 LOC103086718 LOC103086718 MGST1 MGST1 UCK1 UCK1 DUT DUT NME3 NME3 NME4 NME4 LOC103078662 LOC103078662 GMPS GMPS RRM2 RRM2 CDA CDA LOC103082317 LOC103082317 UCK2 UCK2 NME7 NME7 TK2 TK2 CES2 CES2 MGST3 MGST3 LOC103080780 LOC103080780 LOC103079615 LOC103079615 RRM2B RRM2B UCKL1 UCKL1 TPMT TPMT LOC103076117 LOC103076117 DPYD DPYD TK1 TK1 HPRT1 HPRT1 LOC103090598 LOC103090598 UGT1A1 UGT1A1 CMPK1 CMPK1 NME2 NME2 LOC103071337 LOC103071337 LOC103081163 LOC103081163 LOC103078800 LOC103078800 LOC103075878 LOC103075878 LOC103087422 LOC103087422 LOC103089486 LOC103089486 GSTO2 GSTO2 IMPDH1 IMPDH1 LOC103090726 LOC103090726 GSTM1 GSTM1 RRM1 RRM1 XDH XDH TYMP TYMP UGT2B4 UGT2B4 ITPA ITPA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UGT1A10UDP-glucuronosyltransferase 1-10. (317 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
DPYSDihydropyrimidinase. (519 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (320 aa)
MGST2LOW QUALITY PROTEIN: microsomal glutathione S-transferase 2. (154 aa)
LOC103079434Glutathione S-transferase theta-1-like. (207 aa)
LOC103071327UDP-glucuronosyltransferase 1-3-like. (312 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
GSTM3Glutathione S-transferase. (225 aa)
LOC103072071Nucleoside diphosphate kinase. (141 aa)
MPOMyeloperoxidase. (719 aa)
LOC103082472Glutathione S-transferase theta-1-like; Belongs to the GST superfamily. (240 aa)
LOC103078149Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like. (100 aa)
LOC103081925Glutathione S-transferase theta-1-like; Belongs to the GST superfamily. (195 aa)
GSTA4Glutathione S-transferase A4. (223 aa)
LOC103078627UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
UMPSUridine 5'-monophosphate synthase. (480 aa)
LOC103070610Glutathione S-transferase P-like; Belongs to the GST superfamily. (237 aa)
LOC103079831Glutathione S-transferase P-like; Belongs to the GST superfamily. (282 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (309 aa)
LOC103082194Glutathione S-transferase theta-4-like; Belongs to the GST superfamily. (241 aa)
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (652 aa)
UPB1Beta-ureidopropionase. (384 aa)
GSTA2Glutathione S-transferase. (223 aa)
LOC103086718Cytochrome P450 2E1-like; Belongs to the cytochrome P450 family. (495 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
UCK1Uridine-cytidine kinase 1. (268 aa)
DUTDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial. (185 aa)
NME3Nucleoside diphosphate kinase. (169 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
LOC103078662Deoxyuridine 5'-triphosphate nucleotidohydrolase-like. (150 aa)
GMPSGMP synthase [glutamine-hydrolyzing]. (714 aa)
RRM2Ribonucleoside-diphosphate reductase subunit M2 isoform X3. (393 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
LOC103082317Arylamine N-acetyltransferase 1-like isoform X1; Belongs to the arylamine N-acetyltransferase family. (290 aa)
UCK2Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
NME7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (376 aa)
TK2Thymidine kinase 2, mitochondrial isoform X1. (264 aa)
CES2Cocaine esterase. (560 aa)
MGST3Microsomal glutathione S-transferase 3. (152 aa)
LOC103080780Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (519 aa)
LOC103079615Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (254 aa)
RRM2BRibonucleoside-diphosphate reductase subunit M2 B isoform X2. (351 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (533 aa)
TPMTThiopurine S-methyltransferase. (245 aa)
LOC103076117Hypoxanthine-guanine-xanthine phosphoribosyltransferase-like. (201 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
TK1Thymidine kinase. (237 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (176 aa)
LOC103090598Hypoxanthine-guanine-xanthine phosphoribosyltransferase-like. (185 aa)
UGT1A1UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (533 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa)
NME2Nucleoside diphosphate kinase. (152 aa)
LOC103071337Glutathione S-transferase 1, isoform D-like; Belongs to the GST superfamily. (200 aa)
LOC103081163Nucleoside diphosphate kinase. (152 aa)
LOC103078800Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (541 aa)
LOC103075878Glutathione S-transferase U2-like; Belongs to the GST superfamily. (244 aa)
LOC103087422Glutathione S-transferase 3-like. (182 aa)
LOC103089486Glutathione S-transferase U4-like; Belongs to the GST superfamily. (219 aa)
GSTO2Glutathione S-transferase omega-2 isoform X1; Belongs to the GST superfamily. (216 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (571 aa)
LOC103090726Probable glutathione S-transferase GSTF1-like. (207 aa)
GSTM1LOW QUALITY PROTEIN: glutathione S-transferase mu 1; Belongs to the GST superfamily. (226 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (798 aa)
XDHXanthine dehydrogenase/oxidase isoform X1. (1334 aa)
TYMPLOW QUALITY PROTEIN: thymidine phosphorylase. (266 aa)
UGT2B4LOW QUALITY PROTEIN: UDP glucuronosyltransferase 2 family, polypeptide B4. (408 aa)
ITPAInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (209 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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