STRINGSTRING
POLD2 POLD2 RFC1 RFC1 POLD3 POLD3 PMS2 PMS2 POLD4 POLD4 LOC103084651 LOC103084651 RPA3 RPA3 PCNA PCNA RFC4 RFC4 LOC103071096 LOC103071096 RPA1 RPA1 RFC5 RFC5 RPA4 RPA4 MSH2 MSH2 MSH6 MSH6 MLH3 MLH3 RPA2 RPA2 EXO1 EXO1 MLH1 MLH1 LIG1 LIG1 RFC3 RFC3 POLD1 POLD1 SSBP1 SSBP1 RFC2 RFC2 MSH3 MSH3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLD2DNA polymerase delta subunit 2 isoform X1. (469 aa)
RFC1Replication factor C subunit 1. (1245 aa)
POLD3DNA polymerase delta subunit 3. (469 aa)
PMS2Mismatch repair endonuclease PMS2. (865 aa)
POLD4DNA polymerase delta subunit 4. (107 aa)
LOC103084651ATP-dependent DNA helicase srs2-like. (707 aa)
RPA3Replication protein A 14 kDa subunit. (121 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
RFC4Replication factor C subunit 4. (364 aa)
LOC103071096DNA mismatch repair protein Msh3-like. (511 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
RFC5Replication factor C subunit 5. (342 aa)
RPA4Replication protein A 30 kDa subunit. (259 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa)
MLH3DNA mismatch repair protein Mlh3. (1453 aa)
RPA2Replication protein A 32 kDa subunit. (270 aa)
EXO1Exonuclease 1. (835 aa)
MLH1DNA mismatch repair protein Mlh1 isoform X1. (757 aa)
LIG1DNA ligase. (921 aa)
RFC3Replication factor C subunit 3. (356 aa)
POLD1DNA polymerase. (1107 aa)
SSBP1Single-stranded DNA-binding protein, mitochondrial isoform X1. (148 aa)
RFC2Replication factor C subunit 2 isoform X1. (352 aa)
MSH3DNA mismatch repair protein Msh3-like. (620 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.