STRINGSTRING
RHOA RHOA MAPK8 MAPK8 SOS2 SOS2 SHC3 SHC3 KRAS KRAS FGF16 FGF16 RAPGEF5 RAPGEF5 ARF6 ARF6 RASA2 RASA2 RAB5C RAB5C CALML4 CALML4 SOS1 SOS1 MLLT4 MLLT4 GNG2 GNG2 ANGPT1 ANGPT1 FASLG FASLG BCL2L1 BCL2L1 TBK1 TBK1 TIAM1 TIAM1 RASA1 RASA1 CSF1 CSF1 EXOC2 EXOC2 RASAL2 RASAL2 MAP2K1 MAP2K1 PDGFRB PDGFRB LOC103079728 LOC103079728 RAC1 RAC1 MET MET PRKCB PRKCB VEGFC VEGFC MAPK1 MAPK1 ABL2 ABL2 RAP1A RAP1A CALML6 CALML6 GNB1 GNB1 KITLG KITLG PLA1A PLA1A GNG10 GNG10 NF1 NF1 GNG11 GNG11 PDGFD PDGFD RGL1 RGL1 KDR KDR PIK3R3 PIK3R3 RASGRP3 RASGRP3 FGF17 FGF17 ELK1 ELK1 PIK3CD PIK3CD PLA2G4A PLA2G4A ABL1 ABL1 PLA2G3 PLA2G3 RASSF1 RASSF1 RASGRF2 RASGRF2 KSR1 KSR1 PLCG2 PLCG2 IGF1 IGF1 PAK7 PAK7 PLA2G6 PLA2G6 MAPK3 MAPK3 GNG4 GNG4 PLA2G12B PLA2G12B RALGDS RALGDS GRIN2B GRIN2B EFNA5 EFNA5 LAT LAT TGFA TGFA PRKCA PRKCA IKBKB IKBKB FGF7 FGF7 SHC4 SHC4 KSR2 KSR2 GNG13 GNG13 PDGFRA PDGFRA RAC2 RAC2 PDGFB PDGFB GRB2 GRB2 NGF NGF PIK3R1 PIK3R1 AKT1 AKT1 TEK TEK GAB2 GAB2 PLD2 PLD2 EFNA4 EFNA4 NTRK1 NTRK1 EFNA3 EFNA3 SHC1 SHC1 KIT KIT AKT2 AKT2 IKBKG IKBKG PLA2G2D PLA2G2D EFNA1 EFNA1 PLA2G5 PLA2G5 PRKACB PRKACB RALBP1 RALBP1 GNG8 GNG8 PLA2G4F PLA2G4F RASGRP1 RASGRP1 EFNA2 EFNA2 FGF22 FGF22 VEGFA VEGFA INSR INSR CALM3 CALM3 RASGRF1 RASGRF1 RGL2 RGL2 GRIN1 GRIN1 PRKCG PRKCG CDC42 CDC42 PLA2G2E PLA2G2E PLA2G4B PLA2G4B EPHA2 EPHA2 PLA2G2F PLA2G2F FGF10 FGF10 SHC2 SHC2 MAP2K2 MAP2K2 GNB5 GNB5 PGF PGF RELA RELA FGF20 FGF20 SYNGAP1 SYNGAP1 PIK3R2 PIK3R2 PLA2G4D PLA2G4D RRAS2 RRAS2 PAK6 PAK6 PLA2G4E PLA2G4E AKT3 AKT3 PAK1 PAK1 RASAL3 RASAL3 RIN1 RIN1 RASGRP2 RASGRP2 VEGFB VEGFB PLA2G16 PLA2G16 PLA2G12A PLA2G12A NTF4 NTF4 RAF1 RAF1 RAP1B RAP1B LOC103079421 LOC103079421 EGFR EGFR GNG3 GNG3 PDGFC PDGFC BAD BAD NRAS NRAS FLT3LG FLT3LG RRAS RRAS RAC3 RAC3 PAK4 PAK4 PLCG1 PLCG1 GRIN2A GRIN2A RALA RALA FGFR4 FGFR4 EGF EGF FGF21 FGF21 HTR7 HTR7 MAPK9 MAPK9 FGF9 FGF9 MAPK10 MAPK10 ETS1 ETS1 PAK2 PAK2 NFKB1 NFKB1 GAB1 GAB1 NGFR NGFR LOC103081170 LOC103081170 FIGF FIGF REL REL ANGPT4 ANGPT4 MRAS MRAS PIK3CB PIK3CB PAK3 PAK3 PLD1 PLD1 LOC103075492 LOC103075492 BRAP BRAP PLA2G10 PLA2G10 STK4 STK4 PIK3CA PIK3CA FGF4 FGF4 LOC103089724 LOC103089724 FLT4 FLT4 PDGFA PDGFA FGF18 FGF18 FGFR3 FGFR3 LOC103074541 LOC103074541 CALML5 CALML5 HRAS HRAS IGF2 IGF2 INS INS RAB5B RAB5B LOC103069500 LOC103069500 RASA3 RASA3 GNB2 GNB2 GNB4 GNB4 HGF HGF FGF1 FGF1 PRKACA PRKACA LOC103069787 LOC103069787 GNB3 GNB3 FGF6 FGF6 FGF23 FGF23 NTF3 NTF3 RASA4 RASA4 IGF1R IGF1R SHOC2 SHOC2 RALB RALB ETS2 ETS2 FGF2 FGF2 FGFR2 FGFR2 ANGPT2 ANGPT2 RASAL1 RASAL1 PTPN11 PTPN11 FGFR1 FGFR1 LOC103088976 LOC103088976 ZAP70 ZAP70 CHUK CHUK PLCE1 PLCE1 FGF8 FGF8 FOXO4 FOXO4 RASSF5 RASSF5 FLT3 FLT3 PLA2G2C PLA2G2C RASGRP4 RASGRP4 RAB5A RAB5A CALM1 CALM1 FLT1 FLT1 FGF3 FGF3 FGF5 FGF5 BDNF BDNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHOATransforming protein RhoA isoform X1. (221 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
SOS2Son of sevenless homolog 2-like. (1272 aa)
SHC3SHC-transforming protein 3. (588 aa)
KRASGTPase KRas. (188 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (730 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
RASA2Ras GTPase-activating protein 2 isoform X1. (857 aa)
RAB5CRas-related protein Rab-5C. (216 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
MLLT4LOW QUALITY PROTEIN: afadin. (1714 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
ANGPT1Angiopoietin-1 isoform X1. (498 aa)
FASLGTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa)
BCL2L1Bcl-2-like protein 1 isoform X1. (233 aa)
TBK1Serine/threonine-protein kinase TBK1 isoform X1. (753 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1 isoform X1. (1592 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (929 aa)
RASAL2Ras GTPase-activating protein nGAP. (1280 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
LOC103079728Phospholipase A(2). (147 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (201 aa)
METHepatocyte growth factor receptor isoform X1. (1412 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
ABL2Tyrosine-protein kinase. (1067 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
CALML6Calmodulin-like protein 6. (190 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1. (340 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
PLA1APhospholipase A1 member A isoform X1. (456 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
NF1Neurofibromin isoform X1. (2841 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
PDGFDPlatelet-derived growth factor D-like isoform X1. (370 aa)
RGL1Ral guanine nucleotide dissociation stimulator-like 1 isoform X1. (800 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
RASGRP3Ras guanyl-releasing protein 3 isoform X1. (740 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (444 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
PLA2G4APhospholipase A2. (749 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
PLA2G3Group 3 secretory phospholipase A2. (516 aa)
RASSF1Ras association domain-containing protein 1 isoform X3. (344 aa)
RASGRF2Ras-specific guanine nucleotide-releasing factor 2. (1239 aa)
KSR1Kinase suppressor of Ras 1. (757 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
IGF1Insulin-like growth factor I isoform X1. (174 aa)
PAK7Non-specific serine/threonine protein kinase. (719 aa)
PLA2G685/88 kDa calcium-independent phospholipase A2. (805 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PLA2G12BGroup XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
RALGDSRal guanine nucleotide dissociation stimulator. (842 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1496 aa)
EFNA5ephrin-A5; Belongs to the ephrin family. (228 aa)
LATLinker for activation of T-cells family member 1. (260 aa)
TGFAProtransforming growth factor alpha. (145 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
SHC4SHC-transforming protein 4 isoform X1. (631 aa)
KSR2Kinase suppressor of Ras 2. (949 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
GAB2GRB2-associated-binding protein 2. (640 aa)
PLD2Phospholipase. (933 aa)
EFNA4ephrin-A4 isoform X1; Belongs to the ephrin family. (204 aa)
NTRK1Tyrosine-protein kinase receptor. (795 aa)
EFNA3ephrin-A3 isoform X1; Belongs to the ephrin family. (238 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
IKBKGNF-kappa-B essential modulator isoform X1. (419 aa)
PLA2G2DPhospholipase A(2). (161 aa)
EFNA1ephrin-A1; Belongs to the ephrin family. (242 aa)
PLA2G5Phospholipase A(2). (138 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta. (274 aa)
RALBP1ralA-binding protein 1. (635 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (80 aa)
PLA2G4FPhospholipase A2. (849 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (797 aa)
EFNA2ephrin-A2; Belongs to the ephrin family. (214 aa)
FGF22LOW QUALITY PROTEIN: fibroblast growth factor 22; Belongs to the heparin-binding growth factors family. (229 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
RASGRF1Ras-specific guanine nucleotide-releasing factor 1 isoform X2. (1273 aa)
RGL2Ral guanine nucleotide dissociation stimulator-like 2. (780 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
PLA2G2EPhospholipase A(2). (142 aa)
PLA2G4BPhospholipase A2. (780 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
PLA2G2FPhospholipase A(2). (206 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
SHC2SHC-transforming protein 2. (801 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (395 aa)
PGFPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa)
RELATranscription factor p65 isoform X1. (560 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
SYNGAP1ras/Rap GTPase-activating protein SynGAP. (1324 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
PLA2G4DPhospholipase A2. (818 aa)
RRAS2Ras-related protein R-Ras2 isoform X1. (127 aa)
PAK6Non-specific serine/threonine protein kinase. (675 aa)
PLA2G4EPhospholipase A2. (883 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PAK1Non-specific serine/threonine protein kinase. (563 aa)
RASAL3RAS protein activator like-3. (1016 aa)
RIN1Ras and Rab interactor 1. (786 aa)
RASGRP2RAS guanyl-releasing protein 2 isoform X1. (608 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
PLA2G16HRAS-like suppressor 3. (162 aa)
PLA2G12AGroup XIIA secretory phospholipase A2. (188 aa)
NTF4Neurotrophin-4; Belongs to the NGF-beta family. (210 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
LOC103079421Group XIIA secretory phospholipase A2-like. (115 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PDGFCPlatelet-derived growth factor C. (345 aa)
BADBcl2 antagonist of cell death. (168 aa)
NRASGTPase NRas. (189 aa)
FLT3LGFms-related tyrosine kinase 3 ligand isoform X1. (296 aa)
RRASRas-related protein R-Ras. (218 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
PAK4Non-specific serine/threonine protein kinase. (591 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
RALARas-related protein Ral-A. (206 aa)
FGFR4Fibroblast growth factor receptor. (800 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
HTR75-hydroxytryptamine receptor 7 isoform X1; Belongs to the G-protein coupled receptor 1 family. (448 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
ETS1Transforming protein p68/c-ets-1 isoform X1. (485 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (977 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (723 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
LOC103081170Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (465 aa)
FIGFVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
RELProto-oncogene c-Rel. (594 aa)
ANGPT4Angiopoietin-4. (498 aa)
MRASRas-related protein M-Ras isoform X1. (208 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PAK3Serine/threonine-protein kinase PAK 3 isoform X1. (579 aa)
PLD1Phospholipase. (1074 aa)
LOC103075492Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
BRAPBRCA1-associated protein. (592 aa)
PLA2G10Phospholipase A(2). (159 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
LOC103089724Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
FLT4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1594 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGFR3Fibroblast growth factor receptor. (804 aa)
LOC103074541LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
CALML5Calmodulin-like protein 5. (140 aa)
HRASGTPase HRas isoform X1. (189 aa)
IGF2Insulin-like growth factor II isoform X1. (237 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
RAB5BRas-related protein Rab-5B isoform X1. (215 aa)
LOC103069500Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
RASA3Ras GTPase-activating protein 3. (834 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC103069787BDNF/NT-3 growth factors receptor-like isoform X1. (553 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (244 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (266 aa)
RASA4Ras GTPase-activating protein 4 isoform X1. (802 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
SHOC2Leucine-rich repeat protein SHOC-2 isoform X1. (582 aa)
RALBRas-related protein Ral-B. (206 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (472 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
FGFR2Fibroblast growth factor receptor. (839 aa)
ANGPT2Angiopoietin-2. (496 aa)
RASAL1rasGAP-activating-like protein 1. (813 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
FGFR1Fibroblast growth factor receptor. (837 aa)
LOC103088976Ras-related protein Rap-1b-like isoform X1. (165 aa)
ZAP70Tyrosine-protein kinase. (635 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (747 aa)
PLCE1Phosphoinositide phospholipase C. (2303 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
FOXO4Forkhead box protein O4 isoform X1. (512 aa)
RASSF5Ras association domain-containing protein 5 isoform X1. (420 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
PLA2G2CLOW QUALITY PROTEIN: phospholipase A2, group IIC. (217 aa)
RASGRP4RAS guanyl-releasing protein 4. (677 aa)
RAB5ARas-related protein Rab-5A isoform X1. (215 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (232 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (266 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (248 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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