STRINGSTRING
BMP4 BMP4 IL36RN IL36RN IL1B IL1B IL36G IL36G CCL14 CCL14 IFNAR1 IFNAR1 ACVR1C ACVR1C TNFSF18 TNFSF18 CCL4 CCL4 LOC103068298 LOC103068298 IL1RN IL1RN LOC103069866 LOC103069866 INHA INHA CCR6 CCR6 IL1F10 IL1F10 BMP3 BMP3 IL1A IL1A IL37 IL37 FASLG FASLG TNFRSF4 TNFRSF4 CD40 CD40 ACVR1 ACVR1 CCL5 CCL5 TNFSF4 TNFSF4 BMP7 BMP7 IL10RB IL10RB IL17B IL17B LOC103089570 LOC103089570 CCL15 CCL15 TNFRSF18 TNFRSF18 GDF5 GDF5 IFNAR2 IFNAR2 IL6 IL6 RELT RELT CSF1 CSF1 GHR GHR TNFRSF13B TNFRSF13B LOC103076248 LOC103076248 CCR10 CCR10 LOC103083537 LOC103083537 IL33 IL33 IL31 IL31 IL25 IL25 IL17RE IL17RE TNFRSF11B TNFRSF11B ACKR4 ACKR4 IL5RA IL5RA TNFSF8 TNFSF8 TNFSF15 TNFSF15 LOC103068971 LOC103068971 CXCR4 CXCR4 IFNGR1 IFNGR1 IL21R IL21R ACVRL1 ACVRL1 ACKR3 ACKR3 CLCF1 CLCF1 LOC103090205 LOC103090205 LOC103081295 LOC103081295 TNFRSF25 TNFRSF25 IL13RA2 IL13RA2 IL17RC IL17RC BMP15 BMP15 LOC103079191 LOC103079191 LOC103068417 LOC103068417 IL20RA IL20RA CXCR2 CXCR2 IL2RB IL2RB IL17A IL17A LOC103069631 LOC103069631 TNFRSF13C TNFRSF13C TNFRSF21 TNFRSF21 IL17F IL17F LOC103090474 LOC103090474 CD40LG CD40LG GDF6 GDF6 LOC103090661 LOC103090661 LOC103068895 LOC103068895 IL27 IL27 LOC103084028 LOC103084028 TNFRSF12A TNFRSF12A CTF1 CTF1 IFNE IFNE LOC103069739 LOC103069739 IL4R IL4R IL9R IL9R CXCL11 CXCL11 CSF3R CSF3R CXCL13 CXCL13 GDF2 GDF2 CSF2RB CSF2RB IL12A IL12A GDF10 GDF10 LOC103084127 LOC103084127 LOC103089261 LOC103089261 BMP8B BMP8B LOC103090392 LOC103090392 LOC103068617 LOC103068617 EDAR EDAR ACVR2A ACVR2A NODAL NODAL NGF NGF IL1RL2 IL1RL2 LOC103091202 LOC103091202 LOC103069181 LOC103069181 LOC103073219 LOC103073219 CNTF CNTF LOC103073772 LOC103073772 IL7 IL7 CXCL10 CXCL10 CXCL9 CXCL9 IL6R IL6R TGFBR2 TGFBR2 BMPR1A BMPR1A CCL11 CCL11 IFNK IFNK CCL2 CCL2 CXCR5 CXCR5 IL10RA IL10RA LOC103069948 LOC103069948 IL18R1 IL18R1 IL18RAP IL18RAP GH1 GH1 IL1RL1 IL1RL1 LTB LTB LTA LTA TGFB3 TGFB3 IL20RB IL20RB TNFRSF11A TNFRSF11A TNFSF12 TNFSF12 IL12RB2 IL12RB2 CXCL16 CXCL16 TNFSF13 TNFSF13 IL22RA1 IL22RA1 XCL1 XCL1 LOC103075456 LOC103075456 TNFSF14 TNFSF14 CD70 CD70 CCL25 CCL25 CXCL17 CXCL17 EPOR EPOR TNF TNF TGFB1 TGFB1 IL12RB1 IL12RB1 GDF1 GDF1 TNFRSF10A TNFRSF10A IL13 IL13 GDF9 GDF9 LEPR LEPR IL23R IL23R IFNLR1 IFNLR1 CXCR3 CXCR3 TGFBR1 TGFBR1 IL7R IL7R TNFRSF6B TNFRSF6B GDF15 GDF15 LIF LIF OSM OSM IL3RA IL3RA IL9 IL9 TNFSF13B TNFSF13B TNFRSF17 TNFRSF17 AMH AMH LOC103075576 LOC103075576 CSF2RA CSF2RA CRLF2 CRLF2 IL34 IL34 TNFSF9 TNFSF9 LOC103070856 LOC103070856 LOC103071959 LOC103071959 IL4 IL4 IL3 IL3 IFNG IFNG CSF2 CSF2 IL5 IL5 CXCL14 CXCL14 CCL28 CCL28 GDF7 GDF7 ACVR2B ACVR2B IL15 IL15 BMP10 BMP10 PPBP PPBP PF4 PF4 BMPR1B BMPR1B IL18 IL18 IL22 IL22 IL2 IL2 LOC103071404 LOC103071404 CSF3 CSF3 TNFRSF1B TNFRSF1B TNFRSF8 TNFRSF8 LOC103071675 LOC103071675 IL26 IL26 IL15RA IL15RA TNFSF10 TNFSF10 CCR4 CCR4 NGFR NGFR BMP6 BMP6 IL12B IL12B LOC103073060 LOC103073060 MSTN MSTN CCR7 CCR7 IL13RA1 IL13RA1 INHBE INHBE GDF11 GDF11 LOC103071897 LOC103071897 LOC103081180 LOC103081180 IL2RA IL2RA PRLR PRLR CX3CR1 CX3CR1 IL1RAP IL1RAP INHBA INHBA CX3CL1 CX3CL1 LOC103080261 LOC103080261 CCL24 CCL24 THPO THPO INHBC INHBC IFNGR2 IFNGR2 BMPR2 BMPR2 EPO EPO IL11 IL11 GDF3 GDF3 CCR8 CCR8 TNFRSF1A TNFRSF1A CCL22 CCL22 IL23A IL23A IL8 IL8 LIFR LIFR CD4 CD4 CCL26 CCL26 IL17RA IL17RA EDA2R EDA2R LEP LEP CCR9 CCR9 CCR3 CCR3 FAS FAS IL17C IL17C TNFSF11 TNFSF11 MPL MPL IL24 IL24 IL11RA IL11RA IL27RA IL27RA CCR2 CCR2 BMP2 BMP2 IL6ST IL6ST IL2RG IL2RG EDA EDA CXCR6 CXCR6 CCR5 CCR5 LTBR LTBR CD27 CD27 IL16 IL16 INHBB INHBB XCR1 XCR1 CNTFR CNTFR IL10 IL10 CCL21 CCL21 CCR1 CCR1 TGFB2 TGFB2 TNFRSF19 TNFRSF19 IFNL3 IFNL3 IL19 IL19 IL20 IL20 CCL19 CCL19 IFNL1 IFNL1 CCL3 CCL3 BMP5 BMP5 IL32 IL32 CCL27 CCL27 IL17RB IL17RB IL31RA IL31RA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
IL36RNLOW QUALITY PROTEIN: interleukin-36 receptor antagonist protein. (179 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
IL36GInterleukin-1. (172 aa)
CCL14LOW QUALITY PROTEIN: c-C motif chemokine 14. (101 aa)
IFNAR1Interferon alpha/beta receptor 1. (562 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
TNFSF18Tumor necrosis factor ligand superfamily member 18. (178 aa)
CCL4C-C motif chemokine. (92 aa)
LOC103068298Prolactin-like isoform X1. (230 aa)
IL1RNInterleukin-1. (177 aa)
LOC103069866Interleukin-1. (124 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (364 aa)
CCR6c-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (370 aa)
IL1F10Interleukin-1. (144 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (265 aa)
IL37Interleukin-37. (198 aa)
FASLGTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa)
TNFRSF4Tumor necrosis factor receptor superfamily member 4. (278 aa)
CD40Tumor necrosis factor receptor superfamily member 5. (280 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
CCL5C-C motif chemokine. (91 aa)
TNFSF4Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (182 aa)
BMP7Bone morphogenetic protein 7 isoform X1. (431 aa)
IL10RBLOW QUALITY PROTEIN: interleukin-10 receptor subunit beta. (396 aa)
IL17Binterleukin-17B. (180 aa)
LOC103089570C-C motif chemokine. (90 aa)
CCL15C-C motif chemokine. (126 aa)
TNFRSF18Tumor necrosis factor receptor superfamily member 18 isoform X1. (233 aa)
GDF5Growth/differentiation factor 5. (499 aa)
IFNAR2LOW QUALITY PROTEIN: interferon alpha/beta receptor 2. (528 aa)
IL6LOW QUALITY PROTEIN: interleukin-6. (243 aa)
RELTTumor necrosis factor receptor superfamily member 19L. (429 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa)
GHRGrowth hormone receptor isoform X1. (843 aa)
TNFRSF13BTumor necrosis factor receptor superfamily member 13B. (334 aa)
LOC103076248Tumor necrosis factor receptor superfamily member 10A-like. (129 aa)
CCR10c-C chemokine receptor type 10; Belongs to the G-protein coupled receptor 1 family. (363 aa)
LOC103083537Interleukin-13-like. (81 aa)
IL33LOW QUALITY PROTEIN: interleukin-33. (485 aa)
IL31LOW QUALITY PROTEIN: interleukin-31. (125 aa)
IL25Interleukin-25. (117 aa)
IL17REInterleukin-17 receptor E. (626 aa)
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)
ACKR4Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
IL5RAInterleukin-5 receptor subunit alpha. (565 aa)
TNFSF8Tumor necrosis factor ligand superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa)
TNFSF15Tumor necrosis factor ligand superfamily member 15. (256 aa)
LOC103068971Interferon lambda-3-like. (260 aa)
CXCR4c-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
IFNGR1LOW QUALITY PROTEIN: interferon gamma receptor 1. (471 aa)
IL21RInterleukin-21 receptor. (540 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
CLCF1Cardiotrophin-like cytokine factor 1. (215 aa)
LOC103090205Uncharacterized protein LOC103090205. (298 aa)
LOC103081295C-C motif chemokine. (97 aa)
TNFRSF25Tumor necrosis factor receptor superfamily member 25-like. (459 aa)
IL13RA2LOW QUALITY PROTEIN: interleukin-13 receptor subunit alpha-2. (387 aa)
IL17RCInterleukin-17 receptor C isoform X1. (700 aa)
BMP15Bone morphogenetic protein 15. (403 aa)
LOC103079191Bone morphogenetic protein 8B-like. (180 aa)
LOC103068417c-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family. (334 aa)
IL20RAInterleukin-20 receptor subunit alpha. (560 aa)
CXCR2c-X-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (328 aa)
IL2RBInterleukin-2 receptor subunit beta. (574 aa)
IL17Ainterleukin-17A-like. (153 aa)
LOC103069631c-C motif chemokine 1-like. (93 aa)
TNFRSF13CTumor necrosis factor receptor superfamily member 13C. (187 aa)
TNFRSF21Tumor necrosis factor receptor superfamily member 21. (652 aa)
IL17Finterleukin-17F. (165 aa)
LOC103090474LOW QUALITY PROTEIN: cardiotrophin-2-like. (253 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
GDF6Growth/differentiation factor 6. (461 aa)
LOC103090661Interferon alpha-1-like. (189 aa)
LOC103068895Interferon omega-1-like. (227 aa)
IL27Interleukin-27 subunit alpha. (237 aa)
LOC103084028LOW QUALITY PROTEIN: interleukin-1 receptor type 1-like. (592 aa)
TNFRSF12ATumor necrosis factor receptor superfamily member 12A isoform X1. (156 aa)
CTF1Cardiotrophin-1. (185 aa)
IFNEInterferon epsilon. (193 aa)
LOC103069739Interferon alpha-1-like. (189 aa)
IL4RInterleukin-4 receptor subunit alpha isoform X2. (832 aa)
IL9RInterleukin-9 receptor-like. (606 aa)
CXCL11c-X-C motif chemokine 11. (100 aa)
CSF3RGranulocyte colony-stimulating factor receptor. (841 aa)
CXCL13c-X-C motif chemokine 13. (109 aa)
GDF2Growth/differentiation factor 2. (431 aa)
CSF2RBCytokine receptor common subunit beta. (896 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (257 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (440 aa)
LOC103084127Interleukin; Belongs to the IL-15/IL-21 family. (146 aa)
LOC103089261Bone morphogenetic protein 8B-like. (403 aa)
BMP8BBone morphogenetic protein 8B. (403 aa)
LOC103090392Interferon omega-1-like. (195 aa)
LOC103068617Interferon alpha-1-like. (188 aa)
EDARTumor necrosis factor receptor superfamily member EDAR. (448 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
NODALNodal homolog. (349 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
IL1RL2Interleukin-1 receptor-like 2. (569 aa)
LOC103091202Interferon alpha-1-like. (188 aa)
LOC103069181Interferon alpha-1-like. (189 aa)
LOC103073219LOW QUALITY PROTEIN: interferon alpha-8-like. (248 aa)
CNTFCiliary neurotrophic factor. (200 aa)
LOC103073772Interferon beta-2-like. (186 aa)
IL7Interleukin-7 isoform X2. (178 aa)
CXCL10C-X-C motif chemokine. (103 aa)
CXCL9C-X-C motif chemokine. (126 aa)
IL6RInterleukin-6 receptor subunit alpha. (499 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (591 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
CCL11C-C motif chemokine. (99 aa)
IFNKInterferon kappa. (207 aa)
CCL2C-C motif chemokine. (99 aa)
CXCR5c-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (374 aa)
IL10RAInterleukin-10 receptor subunit alpha. (583 aa)
LOC103069948LOW QUALITY PROTEIN: interleukin-1 receptor type 2-like. (450 aa)
IL18R1Interleukin-18 receptor 1. (538 aa)
IL18RAPLOW QUALITY PROTEIN: interleukin-18 receptor accessory protein. (598 aa)
GH1Somatotropin. (216 aa)
IL1RL1Interleukin-1 receptor-like 1. (327 aa)
LTBLymphotoxin-beta; Belongs to the tumor necrosis factor family. (247 aa)
LTALymphotoxin-alpha; Belongs to the tumor necrosis factor family. (205 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
IL20RBInterleukin-20 receptor subunit beta. (305 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A. (850 aa)
TNFSF12Tumor necrosis factor ligand superfamily member 12; Belongs to the tumor necrosis factor family. (248 aa)
IL12RB2Interleukin-12 receptor subunit beta-2 isoform X1. (860 aa)
CXCL16c-X-C motif chemokine 16. (251 aa)
TNFSF13Tumor necrosis factor ligand superfamily member 13 isoform X1; Belongs to the tumor necrosis factor family. (247 aa)
IL22RA1Interleukin-22 receptor subunit alpha-1. (581 aa)
XCL1Lymphotactin. (112 aa)
LOC103075456c-C motif chemokine 8-like. (99 aa)
TNFSF14Tumor necrosis factor ligand superfamily member 14 isoform X1. (241 aa)
CD70CD70 antigen; Belongs to the tumor necrosis factor family. (192 aa)
CCL25c-C motif chemokine 25. (151 aa)
CXCL17VEGF coregulated chemokine 1. (119 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (509 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
IL12RB1Interleukin-12 receptor subunit beta-1. (726 aa)
GDF1Embryonic growth/differentiation factor 1. (370 aa)
TNFRSF10ATumor necrosis factor receptor superfamily member 10A. (426 aa)
IL13Interleukin-13. (132 aa)
GDF9Growth/differentiation factor 9. (454 aa)
LEPRLeptin receptor isoform X1. (1165 aa)
IL23RInterleukin-23 receptor. (630 aa)
IFNLR1Interferon lambda receptor 1 isoform X1. (515 aa)
CXCR3c-X-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (366 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
IL7RInterleukin-7 receptor subunit alpha. (459 aa)
TNFRSF6BLOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 6B. (294 aa)
GDF15Growth/differentiation factor 15. (308 aa)
LIFLeukemia inhibitory factor. (202 aa)
OSMoncostatin-M. (246 aa)
IL3RAInterleukin-3 receptor subunit alpha. (385 aa)
IL9Interleukin-9. (141 aa)
TNFSF13BTumor necrosis factor ligand superfamily member 13B isoform X1; Belongs to the tumor necrosis factor family. (283 aa)
TNFRSF17Tumor necrosis factor receptor superfamily member 17. (179 aa)
AMHMuellerian-inhibiting factor. (558 aa)
LOC103075576Tumor necrosis factor receptor superfamily member 10A-like. (266 aa)
CSF2RAGranulocyte-macrophage colony-stimulating factor receptor subunit alpha. (429 aa)
CRLF2Cytokine receptor-like factor 2. (367 aa)
IL34LOW QUALITY PROTEIN: interleukin-34. (268 aa)
TNFSF9Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family. (284 aa)
LOC103070856C-X-C motif chemokine. (113 aa)
LOC103071959C-X-C motif chemokine. (100 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (133 aa)
IL3Interleukin-3. (144 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
CXCL14c-X-C motif chemokine 14. (99 aa)
CCL28C-C motif chemokine. (127 aa)
GDF7Growth/differentiation factor 7. (457 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (180 aa)
BMP10Bone morphogenetic protein 10. (421 aa)
PPBPC-X-C motif chemokine. (119 aa)
PF4C-X-C motif chemokine. (112 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
IL22Interleukin-22. (189 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
LOC103071404C-X-C motif chemokine. (227 aa)
CSF3Granulocyte colony-stimulating factor. (195 aa)
TNFRSF1BTumor necrosis factor receptor superfamily member 1B isoform X1. (453 aa)
TNFRSF8Tumor necrosis factor receptor superfamily member 8. (487 aa)
LOC103071675C-X-C motif chemokine. (196 aa)
IL26Interleukin-26. (170 aa)
IL15RAInterleukin-15 receptor subunit alpha. (307 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (288 aa)
CCR4c-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (359 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (427 aa)
BMP6Bone morphogenetic protein 6. (495 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
LOC103073060Synaptopodin 2-like protein-like. (392 aa)
MSTNGrowth/differentiation factor 8. (366 aa)
CCR7c-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
IL13RA1Interleukin-13 receptor subunit alpha-1. (424 aa)
INHBEInhibin beta E chain. (351 aa)
GDF11Growth/differentiation factor 11. (404 aa)
LOC103071897Stromal cell-derived factor 1-like isoform X2; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
LOC103081180oncostatin-M-specific receptor subunit beta-like. (636 aa)
IL2RAInterleukin-2 receptor subunit alpha. (277 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (625 aa)
CX3CR1CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
IL1RAPInterleukin-1 receptor accessory protein isoform X2. (687 aa)
INHBALOW QUALITY PROTEIN: inhibin beta A chain. (430 aa)
CX3CL1Fractalkine. (388 aa)
LOC103080261C-C motif chemokine. (201 aa)
CCL24c-C motif chemokine 24. (130 aa)
THPOThrombopoietin isoform X1. (319 aa)
INHBCInhibin beta C chain. (352 aa)
IFNGR2LOW QUALITY PROTEIN: interferon gamma receptor 2. (349 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
IL11Interleukin-11 isoform X1. (199 aa)
GDF3Growth/differentiation factor 3. (364 aa)
CCR8c-C chemokine receptor type 8; Belongs to the G-protein coupled receptor 1 family. (353 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (445 aa)
CCL22C-C motif chemokine. (93 aa)
IL23AInterleukin-23 subunit alpha. (187 aa)
IL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
LIFRLeukemia inhibitory factor receptor. (1096 aa)
CD4T-cell surface glycoprotein CD4. (454 aa)
CCL26c-C motif chemokine 26. (94 aa)
IL17RAInterleukin-17 receptor A. (1132 aa)
EDA2RTumor necrosis factor receptor superfamily member 27-like isoform X1. (321 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
CCR9c-C chemokine receptor type 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
CCR3c-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (358 aa)
FASTumor necrosis factor receptor superfamily member 6. (342 aa)
IL17Cinterleukin-17C. (344 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
MPLThrombopoietin receptor. (645 aa)
IL24Interleukin-24. (177 aa)
IL11RAInterleukin-11 receptor subunit alpha isoform X1. (422 aa)
IL27RAInterleukin-27 receptor subunit alpha. (656 aa)
CCR2LOW QUALITY PROTEIN: c-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
IL6STInterleukin-6 receptor subunit beta isoform X1. (918 aa)
IL2RGCytokine receptor common subunit gamma. (381 aa)
EDAectodysplasin-A isoform X1; Belongs to the tumor necrosis factor family. (391 aa)
CXCR6c-X-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (341 aa)
CCR5c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
LTBRTumor necrosis factor receptor superfamily member 3. (421 aa)
CD27CD27 antigen. (251 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1325 aa)
INHBBInhibin beta B chain. (511 aa)
XCR1Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
CNTFRCiliary neurotrophic factor receptor subunit alpha isoform X1. (372 aa)
IL10Interleukin-10. (178 aa)
CCL21c-C motif chemokine 21. (131 aa)
CCR1c-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TNFRSF19Tumor necrosis factor receptor superfamily member 19. (425 aa)
IFNL3LOW QUALITY PROTEIN: interferon, lambda 3. (313 aa)
IL19Interleukin-19. (177 aa)
IL20LOW QUALITY PROTEIN: interleukin-20. (180 aa)
CCL19C-C motif chemokine. (100 aa)
IFNL1LOW QUALITY PROTEIN: interferon, lambda 1. (192 aa)
CCL3LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3. (88 aa)
BMP5Bone morphogenetic protein 5 isoform X1. (454 aa)
IL32LOW QUALITY PROTEIN: interleukin 32. (184 aa)
CCL27LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 27. (95 aa)
IL17RBLOW QUALITY PROTEIN: interleukin 17 receptor B. (446 aa)
IL31RALOW QUALITY PROTEIN: interleukin 31 receptor A. (268 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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