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| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | SOS2 | Son of sevenless homolog 2-like. (1272 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa) |
| | PLK4 | Serine/threonine-protein kinase PLK4 isoform X1. (973 aa) |
| | KRAS | GTPase KRas. (188 aa) |
| | SETD7 | Histone-lysine N-methyltransferase SETD7-like isoform X1. (407 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | SOS1 | Son of sevenless homolog 1. (1333 aa) |
| | FOXO3 | Forkhead box protein O3. (672 aa) |
| | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3 isoform X3. (482 aa) |
| | PRKAB2 | 5'-AMP-activated protein kinase subunit beta-2. (272 aa) |
| | LOC103079897 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (198 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | SGK3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa) |
| | STAT3 | Signal transducer and activator of transcription. (654 aa) |
| | IL6 | LOW QUALITY PROTEIN: interleukin-6. (243 aa) |
| | LOC103082901 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (707 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (640 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) |
| | BCL6 | B-cell lymphoma 6 protein isoform X1. (728 aa) |
| | CCNB3 | LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1367 aa) |
| | MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (263 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (647 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa) |
| | IRS2 | Insulin receptor substrate 2. (1362 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa) |
| | S1PR1 | Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 isoform X2. (336 aa) |
| | G6PC | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (604 aa) |
| | GRM1 | Metabotropic glutamate receptor 1 isoform X1. (1194 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf isoform X2. (609 aa) |
| | PIK3R3 | LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa) |
| | LOC103076886 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (497 aa) |
| | SGK1 | Non-specific serine/threonine protein kinase. (527 aa) |
| | CREBBP | CREB-binding protein isoform X1. (2429 aa) |
| | LOC103082019 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (574 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (350 aa) |
| | LOC103090122 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like. (196 aa) |
| | EP300 | Histone acetyltransferase p300. (2420 aa) |
| | IGF1 | Insulin-like growth factor I isoform X1. (174 aa) |
| | CSNK1E | Casein kinase I isoform epsilon isoform X2; Belongs to the protein kinase superfamily. (416 aa) |
| | G6PC2 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (325 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (692 aa) |
| | G6PC3 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa) |
| | CCNG2 | cyclin-G2; Belongs to the cyclin family. (344 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa) |
| | FOXO6 | LOW QUALITY PROTEIN: forkhead box protein O6. (552 aa) |
| | LOC103069928 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (711 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | LOC103090756 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (479 aa) |
| | CDKN2B | Cyclin-dependent kinase 4 inhibitor B. (131 aa) |
| | CCNB1 | G2/mitotic-specific cyclin-B1 isoform X1; Belongs to the cyclin family. (433 aa) |
| | LOC103081682 | Gamma-aminobutyric acid receptor-associated protein-like 1-like. (60 aa) |
| | FBXO32 | F-box only protein 32 isoform X1. (355 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (591 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) |
| | SIRT1 | LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1. (695 aa) |
| | GABARAP | Gamma-aminobutyric acid receptor-associated protein. (117 aa) |
| | TGFB3 | Transforming growth factor beta-3. (456 aa) |
| | SLC2A4 | Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (550 aa) |
| | CCNB2 | G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (398 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1382 aa) |
| | RBL2 | Retinoblastoma-like protein 2 isoform X1. (1141 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | HOMER3 | Homer protein homolog 3 isoform X1. (360 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa) |
| | IL7R | Interleukin-7 receptor subunit alpha. (459 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | SKP2 | S-phase kinase-associated protein 2 isoform X1. (436 aa) |
| | CDKN2D | Cyclin-dependent kinase 4 inhibitor D. (166 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa) |
| | S1PR4 | Sphingosine 1-phosphate receptor 4 isoform X1. (385 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | STK11 | Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (438 aa) |
| | GABARAPL2 | Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa) |
| | SOD2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa) |
| | KLF2 | Krueppel-like factor 2. (355 aa) |
| | PRMT1 | Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | IRS4 | Insulin receptor substrate 4 isoform X1. (1267 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | PRKAB1 | 5'-AMP-activated protein kinase subunit beta-1. (270 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (553 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | LOC103073063 | Forkhead box protein G1-like isoform X1. (483 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (288 aa) |
| | SGK2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | RAG2 | V(D)J recombination-activating protein 2. (527 aa) |
| | STK4 | Serine/threonine-protein kinase 4. (487 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | AGAP2 | arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2-like isoform X1. (1193 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | IRS1 | Insulin receptor substrate 1. (1252 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf. (763 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1 isoform X1. (164 aa) |
| | PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2 isoform X1. (569 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | FBXO25 | F-box only protein 25 isoform X2. (367 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha. (747 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | USP7 | Ubiquitin carboxyl-terminal hydrolase 7 isoform X1; Belongs to the peptidase C19 family. (1107 aa) |
| | GABARAPL1 | Gamma-aminobutyric acid receptor-associated protein-like 1. (107 aa) |
| | HOMER2 | Homer protein homolog 2 isoform X1. (354 aa) |
| | FOXO4 | Forkhead box protein O4 isoform X1. (512 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | HOMER1 | Homer protein homolog 1. (354 aa) |
| | IL10 | Interleukin-10. (178 aa) |
| | LOC103077612 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (198 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | FOXO1 | Forkhead box protein O1. (655 aa) |
