STRINGSTRING
INPP5D INPP5D IP6K1 IP6K1 CDS1 CDS1 PLCD4 PLCD4 CALML4 CALML4 DGKD DGKD IP6K2 IP6K2 ITPR2 ITPR2 PI4K2B PI4K2B SYNJ1 SYNJ1 PRKCB PRKCB MTMR4 MTMR4 PI4KA PI4KA PIK3C2A PIK3C2A CALML6 CALML6 IPMK IPMK PLCB4 PLCB4 OCRL OCRL PPIP5K2 PPIP5K2 PLCB1 PLCB1 PIK3R3 PIK3R3 DGKG DGKG DGKK DGKK PIK3CD PIK3CD SYNJ2 SYNJ2 MTMR2 MTMR2 MTM1 MTM1 MTMR14 MTMR14 PLCG2 PLCG2 INPP5A INPP5A MTMR1 MTMR1 PIP4K2A PIP4K2A PLCD3 PLCD3 CDIPT CDIPT PRKCA PRKCA CDS2 CDS2 ITPR1 ITPR1 INPP5B INPP5B PIK3C2G PIK3C2G PLCZ1 PLCZ1 ITPK1 ITPK1 PIK3R1 PIK3R1 DGKZ DGKZ PI4K2A PI4K2A ITPKC ITPKC TMEM55A TMEM55A MTMR7 MTMR7 PIP5K1A PIP5K1A PIP5K1C PIP5K1C CALM3 CALM3 PRKCG PRKCG INPP5E INPP5E PLCB2 PLCB2 PI4KB PI4KB PLCB3 PLCB3 IP6K3 IP6K3 ITPKA ITPKA PIK3R2 PIK3R2 LOC103083783 LOC103083783 PLCD1 PLCD1 ITPR3 ITPR3 IMPA2 IMPA2 MTMR3 MTMR3 PIKFYVE PIKFYVE IMPA1 IMPA1 IMPAD1 IMPAD1 PIK3C3 PIK3C3 TMEM55B TMEM55B PLCG1 PLCG1 DGKB DGKB INPPL1 INPPL1 SACM1L SACM1L PIP4K2B PIP4K2B INPP4B INPP4B DGKE DGKE ITPKB ITPKB PIK3CB PIK3CB PIP5K1B PIP5K1B INPP4A INPP4A PIK3CA PIK3CA INPP1 INPP1 LOC103074541 LOC103074541 DGKQ DGKQ CALML5 CALML5 DGKI DGKI PPIP5K1 PPIP5K1 DGKA DGKA PIP4K2C PIP4K2C IPPK IPPK INPP5F INPP5F PTEN PTEN DGKH DGKH PLCE1 PLCE1 PIK3C2B PIK3C2B CALM1 CALM1 MTMR6 MTMR6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1187 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa)
PLCD4Phosphoinositide phospholipase C. (763 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
DGKDDiacylglycerol kinase. (1222 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2-beta. (498 aa)
SYNJ1Synaptojanin-1 isoform X1. (1600 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MTMR4Myotubularin-related protein 4 isoform X1. (1210 aa)
PI4KAPhosphatidylinositol 4-kinase alpha isoform X1; Belongs to the PI3/PI4-kinase family. (2098 aa)
PIK3C2APhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; Belongs to the PI3/PI4-kinase family. (1688 aa)
CALML6Calmodulin-like protein 6. (190 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
OCRLInositol polyphosphate 5-phosphatase OCRL-1 isoform X1. (904 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1263 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
DGKGDiacylglycerol kinase. (791 aa)
DGKKDiacylglycerol kinase. (1229 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
SYNJ2Synaptojanin-2. (1475 aa)
MTMR2Myotubularin-related protein 2 isoform X1. (643 aa)
MTM1Myotubularin isoform X1. (603 aa)
MTMR14Myotubularin-related protein 14 isoform X1. (648 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
INPP5AType I inositol 1,4,5-trisphosphate 5-phosphatase. (412 aa)
MTMR1Myotubularin-related protein 1 isoform X1. (665 aa)
PIP4K2APhosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1. (406 aa)
PLCD3Phosphoinositide phospholipase C. (786 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (251 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
INPP5BLOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase. (1208 aa)
PIK3C2GPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1; Belongs to the PI3/PI4-kinase family. (1483 aa)
PLCZ1Phosphoinositide phospholipase C. (668 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (419 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
DGKZDiacylglycerol kinase. (1120 aa)
PI4K2APhosphatidylinositol 4-kinase type 2-alpha. (493 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (647 aa)
TMEM55APhosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
MTMR7Myotubularin-related protein 7. (660 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (828 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (877 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
PI4KBPhosphatidylinositol 4-kinase beta isoform X1; Belongs to the PI3/PI4-kinase family. (816 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (389 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
LOC103083783CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (217 aa)
PLCD1Phosphoinositide phospholipase C. (721 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
MTMR3LOW QUALITY PROTEIN: myotubularin-related protein 3. (1205 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform X1. (2097 aa)
IMPA1Inositol monophosphatase 1. (464 aa)
IMPAD1Inositol monophosphatase 3. (359 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
TMEM55BPhosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (367 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
DGKBDiacylglycerol kinase beta. (597 aa)
INPPL1LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1264 aa)
SACM1LPhosphatidylinositide phosphatase SAC1 isoform X1. (587 aa)
PIP4K2BPhosphatidylinositol 5-phosphate 4-kinase type-2 beta. (370 aa)
INPP4BType II inositol 3,4-bisphosphate 4-phosphatase. (925 aa)
DGKEDiacylglycerol kinase. (602 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (942 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1. (540 aa)
INPP4AType I inositol 3,4-bisphosphate 4-phosphatase isoform X1. (989 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
INPP1Inositol polyphosphate 1-phosphatase isoform X1. (402 aa)
LOC103074541LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
DGKQDiacylglycerol kinase. (937 aa)
CALML5Calmodulin-like protein 5. (140 aa)
DGKIDiacylglycerol kinase. (1078 aa)
PPIP5K1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1476 aa)
DGKADiacylglycerol kinase. (734 aa)
PIP4K2CPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1. (421 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (491 aa)
INPP5FPhosphatidylinositide phosphatase SAC2. (1134 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
DGKHDiacylglycerol kinase. (1216 aa)
PLCE1Phosphoinositide phospholipase C. (2303 aa)
PIK3C2BPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
MTMR6Myotubularin-related protein 6. (621 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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