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ATG9A ATG9A ATG16L1 ATG16L1 PPP2CB PPP2CB WIPI2 WIPI2 BECN1 BECN1 ATG2B ATG2B ATG12 ATG12 ATG10 ATG10 ATG7 ATG7 ATG101 ATG101 MLST8 MLST8 WIPI1 WIPI1 ATG13 ATG13 LOC103081682 LOC103081682 GABARAP GABARAP ATG3 ATG3 ATG2A ATG2A BECN1P1 BECN1P1 ULK2 ULK2 ATG4D ATG4D GABARAPL2 GABARAPL2 PPP2CA PPP2CA PIK3C3 PIK3C3 ATG4C ATG4C MTOR MTOR RPTOR RPTOR PIK3R4 PIK3R4 ATG4A ATG4A ATG5 ATG5 ATG9B ATG9B ATG4B ATG4B GABARAPL1 GABARAPL1 IGBP1 IGBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (870 aa)
ATG16L1Autophagy-related protein 16-1 isoform X1. (607 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
WIPI2WD repeat domain phosphoinositide-interacting protein 2 isoform X1. (436 aa)
BECN1Beclin-1 isoform X1. (448 aa)
ATG2BAutophagy-related protein 2 homolog B. (2078 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
ATG10Ubiquitin-like-conjugating enzyme ATG10. (234 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (720 aa)
ATG101Autophagy-related protein 101. (218 aa)
MLST8Target of rapamycin complex subunit LST8 isoform X1. (326 aa)
WIPI1WD repeat domain phosphoinositide-interacting protein 1. (447 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (551 aa)
LOC103081682Gamma-aminobutyric acid receptor-associated protein-like 1-like. (60 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
ATG3Autophagy-related protein 3. (314 aa)
ATG2AAutophagy-related protein 2 homolog A. (1938 aa)
BECN1P1Beclin-2. (432 aa)
ULK2Serine/threonine-protein kinase ULK2. (952 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (471 aa)
GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2544 aa)
RPTORRegulatory-associated protein of mTOR isoform X1. (1335 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (910 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1. (107 aa)
IGBP1Immunoglobulin-binding protein 1 isoform X1. (368 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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