STRINGSTRING
RHOA RHOA NEDD4 NEDD4 LOC103079630 LOC103079630 SNX3 SNX3 ARF6 ARF6 SRC SRC CHMP4B CHMP4B RAB5C RAB5C SMAP1 SMAP1 SNX4 SNX4 ARF5 ARF5 PSD4 PSD4 LOC103074096 LOC103074096 ITCH ITCH DNM3 DNM3 ARFGEF2 ARFGEF2 PARD6B PARD6B ARAP1 ARAP1 SMAD3 SMAD3 GRK7 GRK7 KIF5B KIF5B RAB4A RAB4A PML PML FAM21A FAM21A ARAP2 ARAP2 RAB22A RAB22A LOC103070590 LOC103070590 VPS29 VPS29 SPG21 SPG21 LOC103070778 LOC103070778 ARPC1B ARPC1B KIAA1033 KIAA1033 VPS4A VPS4A PDCD6IP PDCD6IP ARPC5 ARPC5 CHMP4A CHMP4A ARFGEF1 ARFGEF1 ASAP1 ASAP1 FOLR4 FOLR4 VPS37B VPS37B GIT2 GIT2 RAB35 RAB35 ARPC1A ARPC1A RAB11FIP1 RAB11FIP1 PARD6G PARD6G CAV2 CAV2 PRKCZ PRKCZ EPN2 EPN2 VTA1 VTA1 VPS35 VPS35 ARPC3 ARPC3 SMURF1 SMURF1 ACAP3 ACAP3 CYTH3 CYTH3 ARPC2 ARPC2 RABEP1 RABEP1 CLTC CLTC CCDC53 CCDC53 LOC103076235 LOC103076235 WIPF1 WIPF1 LOC103086977 LOC103086977 VPS25 VPS25 NEDD4L NEDD4L CXCR4 CXCR4 CAPZA2 CAPZA2 ARPC5L ARPC5L ADRBK1 ADRBK1 GIT1 GIT1 VPS26B VPS26B LOC103088795 LOC103088795 SNX1 SNX1 CAV1 CAV1 LOC103068417 LOC103068417 CXCR2 CXCR2 ARFGAP3 ARFGAP3 ARF3 ARF3 RAB11FIP3 RAB11FIP3 ARPC4 ARPC4 CYTH4 CYTH4 IL2RB IL2RB LOC103086241 LOC103086241 CAPZA3 CAPZA3 RAB11FIP4 RAB11FIP4 AMPH AMPH ARFGAP2 ARFGAP2 RAB11FIP5 RAB11FIP5 SMAP2 SMAP2 PDGFRA PDGFRA CBL CBL ZFYVE27 ZFYVE27 ARRB1 ARRB1 SMURF2 SMURF2 VPS26A VPS26A KIF5C KIF5C KIAA0196 KIAA0196 USP8 USP8 PLD2 PLD2 ARF1 ARF1 TGFBR2 TGFBR2 EHD2 EHD2 CLTA CLTA RAB31 RAB31 LOC103089703 LOC103089703 CAPZA1 CAPZA1 ARRB2 ARRB2 ACAP1 ACAP1 ASAP3 ASAP3 CAPZB CAPZB ASAP2 ASAP2 PARD6A PARD6A HSPA1L HSPA1L CHMP2A CHMP2A IQSEC2 IQSEC2 IGF2R IGF2R CHMP7 CHMP7 PIP5K1A PIP5K1A PIP5K1C PIP5K1C SH3GL1 SH3GL1 AP2S1 AP2S1 DNM2 DNM2 STAMBP STAMBP STAM STAM EPS15L1 EPS15L1 RAB8A RAB8A CBLC CBLC BIN1 BIN1 CDC42 CDC42 DNAJC6 DNAJC6 PSD2 PSD2 LDLRAP1 LDLRAP1 TGFBR1 TGFBR1 LOC103073518 LOC103073518 WWP1 WWP1 ZFYVE9 ZFYVE9 EPS15 EPS15 RAB11B RAB11B SNX32 SNX32 LOC103085165 LOC103085165 VPS37A VPS37A VPS37C VPS37C LOC103083060 LOC103083060 DAB2 DAB2 LOC103071041 LOC103071041 LDLR LDLR ZFYVE20 ZFYVE20 CHMP4C CHMP4C LOC103081344 LOC103081344 IST1 IST1 LOC103080706 LOC103080706 MVB12A MVB12A CLTB CLTB ADRBK2 ADRBK2 CYTH2 CYTH2 CYTH1 CYTH1 MDM2 MDM2 IQSEC1 IQSEC1 CBLB CBLB EGFR EGFR SNX5 SNX5 AGAP1 AGAP1 LOC103082332 LOC103082332 EHD1 EHD1 GRK6 GRK6 SPG20 SPG20 HGS HGS CHMP6 CHMP6 CHMP1B CHMP1B ARFGAP1 ARFGAP1 AP2A1 AP2A1 SNX6 SNX6 CHMP5 CHMP5 EPN3 EPN3 FGFR4 FGFR4 FOLR2 FOLR2 WIPF2 WIPF2 STAM2 STAM2 SH3GLB1 SH3GLB1 VPS45 VPS45 SNX2 SNX2 CAV3 CAV3 TSG101 TSG101 ACAP2 ACAP2 VPS4B VPS4B AP2A2 AP2A2 VPS28 VPS28 PIP5K1B PIP5K1B SH3GL2 SH3GL2 PRKCI PRKCI PLD1 PLD1 SNF8 SNF8 RAB7A RAB7A GRK1 GRK1 RUFY1 RUFY1 FGFR3 FGFR3 SMAD2 SMAD2 TFRC TFRC IL2RA IL2RA AGAP2 AGAP2 KIF5A KIF5A HRAS HRAS RAB5B RAB5B WIPF3 WIPF3 EEA1 EEA1 PSD3 PSD3 EPN1 EPN1 LOC103085022 LOC103085022 CHMP3 CHMP3 AP2M1 AP2M1 CHMP2B CHMP2B RNF41 RNF41 ARAP3 ARAP3 VPS37D VPS37D CHMP1A CHMP1A IQSEC3 IQSEC3 IGF1R IGF1R SNX12 SNX12 GRK5 GRK5 RAB11FIP2 RAB11FIP2 LOC103089154 LOC103089154 LOC103082646 LOC103082646 FGFR2 FGFR2 PSD PSD AGAP3 AGAP3 SH3KBP1 SH3KBP1 LOC103074840 LOC103074840 IL2RG IL2RG CCR5 CCR5 RAB10 RAB10 PARD3 PARD3 SH3GL3 SH3GL3 EHD3 EHD3 GBF1 GBF1 RAB5A RAB5A DNM1 DNM1 VPS36 VPS36 HSPA8 HSPA8 PIP5KL1 PIP5KL1 WASL WASL ZFYVE16 ZFYVE16 SH3GLB2 SH3GLB2 MVB12B MVB12B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHOATransforming protein RhoA isoform X1. (221 aa)
NEDD4E3 ubiquitin-protein ligase. (782 aa)
LOC103079630PH and SEC7 domain-containing protein 3-like. (341 aa)
SNX3Sorting nexin-3 isoform X1. (162 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
SRCTyrosine-protein kinase. (548 aa)
CHMP4BCharged multivesicular body protein 4b. (224 aa)
RAB5CRas-related protein Rab-5C. (216 aa)
SMAP1Stromal membrane-associated protein 1 isoform X1. (472 aa)
SNX4Sorting nexin-4. (450 aa)
ARF5ADP-ribosylation factor 5; Belongs to the small GTPase superfamily. Arf family. (180 aa)
PSD4PH and SEC7 domain-containing protein 4. (1007 aa)
LOC103074096WASH complex subunit CCDC53-like. (192 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
DNM3Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (863 aa)
ARFGEF2Brefeldin A-inhibited guanine nucleotide-exchange protein 2. (1785 aa)
PARD6BPartitioning defective 6 homolog beta. (372 aa)
ARAP1LOW QUALITY PROTEIN: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1. (1452 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (549 aa)
KIF5BKinesin-1 heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1001 aa)
RAB4ARas-related protein Rab-4A. (218 aa)
PMLProtein PML. (848 aa)
FAM21AWASH complex subunit FAM21A isoform X1. (1336 aa)
ARAP2arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2. (1698 aa)
RAB22ARas-related protein Rab-22A. (152 aa)
LOC103070590AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (598 aa)
VPS29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa)
SPG21Maspardin. (197 aa)
LOC103070778ADP-ribosylation factor 4-like; Belongs to the small GTPase superfamily. Arf family. (180 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
KIAA1033WASH complex subunit 7. (1221 aa)
VPS4AVacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (437 aa)
PDCD6IPProgrammed cell death 6-interacting protein isoform X1. (877 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
CHMP4ACharged multivesicular body protein 4a. (222 aa)
ARFGEF1Brefeldin A-inhibited guanine nucleotide-exchange protein 1. (1849 aa)
ASAP1arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1. (1111 aa)
FOLR4Probable folate receptor delta. (277 aa)
VPS37BVacuolar protein sorting-associated protein 37B. (289 aa)
GIT2ARF GTPase-activating protein GIT2 isoform X1. (758 aa)
RAB35Ras-related protein Rab-35 isoform X1. (201 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (387 aa)
RAB11FIP1Rab11 family-interacting protein 1 isoform X1. (1243 aa)
PARD6GPartitioning defective 6 homolog gamma. (371 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
EPN2Epsin-2 isoform X1. (643 aa)
VTA1Vacuolar protein sorting-associated protein VTA1 homolog isoform X1. (309 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
SMURF1E3 ubiquitin-protein ligase SMURF1. (720 aa)
ACAP3LOW QUALITY PROTEIN: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3. (820 aa)
CYTH3Cytohesin-3. (351 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
RABEP1Rab GTPase-binding effector protein 1. (872 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1818 aa)
CCDC53WASH complex subunit CCDC53. (194 aa)
LOC103076235BOLA class I histocompatibility antigen, alpha chain BL3-7-like; Belongs to the MHC class I family. (363 aa)
WIPF1WAS/WASL-interacting protein family member 1-like. (495 aa)
LOC103086977BOLA class I histocompatibility antigen, alpha chain BL3-7-like; Belongs to the MHC class I family. (350 aa)
VPS25Vacuolar protein-sorting-associated protein 25. (176 aa)
NEDD4LE3 ubiquitin-protein ligase. (854 aa)
CXCR4c-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
ADRBK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (692 aa)
GIT1ARF GTPase-activating protein GIT1 isoform X1. (770 aa)
VPS26BVacuolar protein sorting-associated protein 26B. (405 aa)
LOC103088795TNF receptor-associated factor 6-like. (315 aa)
SNX1Sorting nexin-1 isoform X1. (522 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
LOC103068417c-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family. (334 aa)
CXCR2c-X-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (328 aa)
ARFGAP3ADP-ribosylation factor GTPase-activating protein 3 isoform X1. (522 aa)
ARF3ADP-ribosylation factor 3 isoform X1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
RAB11FIP3Rab11 family-interacting protein 3. (686 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (170 aa)
CYTH4Cytohesin-4. (407 aa)
IL2RBInterleukin-2 receptor subunit beta. (574 aa)
LOC103086241ADP-ribosylation factor 4-like; Belongs to the small GTPase superfamily. Arf family. (180 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (298 aa)
RAB11FIP4Rab11 family-interacting protein 4. (810 aa)
AMPHAmphiphysin isoform X1. (685 aa)
ARFGAP2ADP-ribosylation factor GTPase-activating protein 2 isoform X1. (520 aa)
RAB11FIP5Rab11 family-interacting protein 5. (645 aa)
SMAP2Stromal membrane-associated protein 2. (429 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
ZFYVE27Protrudin isoform X1. (418 aa)
ARRB1Beta-arrestin-1. (418 aa)
SMURF2E3 ubiquitin-protein ligase. (747 aa)
VPS26AVacuolar protein sorting-associated protein 26A isoform X1. (329 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (955 aa)
KIAA0196WASH complex subunit strumpellin isoform X1. (1159 aa)
USP8LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1116 aa)
PLD2Phospholipase. (933 aa)
ARF1ADP-ribosylation factor 1 isoform X1; Belongs to the small GTPase superfamily. Arf family. (204 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (591 aa)
EHD2EH domain-containing protein 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (243 aa)
RAB31Ras-related protein Rab-31. (205 aa)
LOC103089703ADP-ribosylation factor 2-like isoform X1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
ARRB2Beta-arrestin-2 isoform X1. (421 aa)
ACAP1arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1. (741 aa)
ASAP3arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X1. (904 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (342 aa)
ASAP2arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform X1. (1007 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (346 aa)
HSPA1LLOW QUALITY PROTEIN: heat shock 70 kDa protein 1-like; Belongs to the heat shock protein 70 family. (634 aa)
CHMP2ACharged multivesicular body protein 2a. (222 aa)
IQSEC2IQ motif and SEC7 domain-containing protein 2 isoform X1. (1488 aa)
IGF2RCation-independent mannose-6-phosphate receptor. (2490 aa)
CHMP7Charged multivesicular body protein 7-like. (450 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (828 aa)
SH3GL1endophilin-A2 isoform X1. (369 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
DNM2Dynamin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (871 aa)
STAMBPSTAM-binding protein isoform X2. (424 aa)
STAMSignal transducing adapter molecule 1. (507 aa)
EPS15L1Epidermal growth factor receptor substrate 15-like 1. (864 aa)
RAB8ARas-related protein Rab-8A. (207 aa)
CBLCE3 ubiquitin-protein ligase CBL-C. (492 aa)
BIN1Myc box-dependent-interacting protein 1 isoform X1. (594 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
DNAJC6Putative tyrosine-protein phosphatase auxilin isoform X1. (971 aa)
PSD2LOW QUALITY PROTEIN: PH and SEC7 domain-containing protein 2. (862 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1. (309 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
LOC103073518Heat shock 70 kDa protein 1B-like; Belongs to the heat shock protein 70 family. (641 aa)
WWP1E3 ubiquitin-protein ligase. (922 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1420 aa)
EPS15Epidermal growth factor receptor substrate 15. (902 aa)
RAB11BRas-related protein Rab-11B. (218 aa)
SNX32Sorting nexin; Involved in several stages of intracellular trafficking. (403 aa)
LOC103085165BOLA class I histocompatibility antigen, alpha chain BL3-7-like isoform X1; Belongs to the MHC class I family. (362 aa)
VPS37AVacuolar protein sorting-associated protein 37A isoform X1. (397 aa)
VPS37CVacuolar protein sorting-associated protein 37C. (345 aa)
LOC103083060BOLA class I histocompatibility antigen, alpha chain BL3-7-like; Belongs to the MHC class I family. (349 aa)
DAB2Disabled homolog 2. (769 aa)
LOC103071041Heat shock-related 70 kDa protein 2-like; Belongs to the heat shock protein 70 family. (638 aa)
LDLRLow-density lipoprotein receptor. (857 aa)
ZFYVE20Rabenosyn-5. (784 aa)
CHMP4CCharged multivesicular body protein 4c. (237 aa)
LOC103081344Folate receptor alpha-like. (251 aa)
IST1IST1 homolog isoform X1. (364 aa)
LOC103080706Folate receptor alpha-like isoform X1. (257 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
ADRBK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
CYTH2Cytohesin-2 isoform X1. (421 aa)
CYTH1Cytohesin-1. (338 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
IQSEC1IQ motif and SEC7 domain-containing protein 1 isoform X1. (1125 aa)
CBLBE3 ubiquitin-protein ligase CBL-B-like. (983 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa)
AGAP1arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1. (878 aa)
LOC103082332ADP-ribosylation factor 4-like; Belongs to the small GTPase superfamily. Arf family. (180 aa)
EHD1EH domain-containing protein 1 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (548 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (595 aa)
SPG20Spartin isoform X1. (668 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
CHMP6Charged multivesicular body protein 6. (202 aa)
CHMP1BCharged multivesicular body protein 1b. (199 aa)
ARFGAP1ADP-ribosylation factor GTPase-activating protein 1. (416 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa)
SNX6Sorting nexin; Involved in several stages of intracellular trafficking. (406 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
EPN3Epsin-3. (604 aa)
FGFR4Fibroblast growth factor receptor. (800 aa)
FOLR2Folate receptor beta. (253 aa)
WIPF2WAS/WASL-interacting protein family member 2 isoform X1. (440 aa)
STAM2Signal transducing adapter molecule 2 isoform X1. (526 aa)
SH3GLB1endophilin-B1 isoform X1. (402 aa)
VPS45Vacuolar protein sorting-associated protein 45 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (570 aa)
SNX2Sorting nexin-2. (519 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
TSG101Tumor susceptibility gene 101 protein. (391 aa)
ACAP2arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2. (780 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (443 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (938 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1. (540 aa)
SH3GL2endophilin-A1. (352 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
PLD1Phospholipase. (1074 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
RUFY1RUN and FYVE domain-containing protein 1. (697 aa)
FGFR3Fibroblast growth factor receptor. (804 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TFRCTransferrin receptor protein 1 isoform X2. (770 aa)
IL2RAInterleukin-2 receptor subunit alpha. (277 aa)
AGAP2arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2-like isoform X1. (1193 aa)
KIF5AKinesin heavy chain isoform 5A isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
HRASGTPase HRas isoform X1. (189 aa)
RAB5BRas-related protein Rab-5B isoform X1. (215 aa)
WIPF3WAS/WASL-interacting protein family member 3. (416 aa)
EEA1Early endosome antigen 1. (1410 aa)
PSD3PH and SEC7 domain-containing protein 3-like. (848 aa)
EPN1Epsin-1 isoform X1. (576 aa)
LOC103085022Charged multivesicular body protein 7-like. (305 aa)
CHMP3Charged multivesicular body protein 3. (221 aa)
AP2M1AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
CHMP2BCharged multivesicular body protein 2b isoform X1. (213 aa)
RNF41E3 ubiquitin-protein ligase NRDP1 isoform X1. (317 aa)
ARAP3arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3. (1546 aa)
VPS37DVacuolar protein sorting-associated protein 37D. (227 aa)
CHMP1ACharged multivesicular body protein 1a. (196 aa)
IQSEC3IQ motif and SEC7 domain-containing protein 3 isoform X1. (1166 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
SNX12Sorting nexin-12 isoform X1. (162 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (589 aa)
RAB11FIP2Rab11 family-interacting protein 2. (513 aa)
LOC103089154arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2-like. (710 aa)
LOC103082646WAS protein family homolog 1-like. (472 aa)
FGFR2Fibroblast growth factor receptor. (839 aa)
PSDPH and SEC7 domain-containing protein 1 isoform X1. (1026 aa)
AGAP3arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3-like isoform X1. (898 aa)
SH3KBP1SH3 domain-containing kinase-binding protein 1 isoform X1. (665 aa)
LOC103074840Heat shock cognate 71 kDa protein-like; Belongs to the heat shock protein 70 family. (634 aa)
IL2RGCytokine receptor common subunit gamma. (381 aa)
CCR5c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
RAB10Ras-related protein Rab-10. (200 aa)
PARD3Partitioning defective 3 homolog isoform X1. (1355 aa)
SH3GL3endophilin-A3. (347 aa)
EHD3EH domain-containing protein 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
GBF1Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X3. (1861 aa)
RAB5ARas-related protein Rab-5A isoform X1. (215 aa)
DNM1Dynamin-1 isoform X3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
VPS36Vacuolar protein-sorting-associated protein 36 isoform X1. (386 aa)
HSPA8LOW QUALITY PROTEIN: heat shock 70kDa protein 8; Belongs to the heat shock protein 70 family. (650 aa)
PIP5KL1Phosphatidylinositol 4-phosphate 5-kinase-like protein 1. (396 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (505 aa)
ZFYVE16Zinc finger FYVE domain-containing protein 16 isoform X1. (1546 aa)
SH3GLB2endophilin-B2 isoform X2. (404 aa)
MVB12BMultivesicular body subunit 12B. (371 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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