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| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | SPTA1 | Spectrin alpha chain, erythrocytic 1-like. (2411 aa) |
| | BCL2A1 | Bcl-2-related protein A1. (175 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa) |
| | KRAS | GTPase KRas. (188 aa) |
| | ACTB | Actin, cytoplasmic 1. (375 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (482 aa) |
| | LOC103082790 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (427 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa) |
| | LOC103089492 | Cathepsin L1-like; Belongs to the peptidase C1 family. (333 aa) |
| | BCL2L1 | Bcl-2-like protein 1 isoform X1. (233 aa) |
| | LOC103079638 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (173 aa) |
| | XIAP | E3 ubiquitin-protein ligase XIAP. (497 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) |
| | LOC103076248 | Tumor necrosis factor receptor superfamily member 10A-like. (129 aa) |
| | LOC103069156 | Cytochrome c 2-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | CTSL | Cathepsin L1; Belongs to the peptidase C1 family. (332 aa) |
| | BIRC3 | Baculoviral IAP repeat-containing protein 3. (604 aa) |
| | MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (263 aa) |
| | BIRC2 | LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 2. (621 aa) |
| | DIABLO | Diablo homolog, mitochondrial isoform X1. (237 aa) |
| | AIFM1 | LOW QUALITY PROTEIN: apoptosis-inducing factor 1, mitochondrial. (613 aa) |
| | CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (303 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | SEPT4 | Septin-4 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (477 aa) |
| | DFFB | DNAation factor subunit beta. (341 aa) |
| | TRAF1 | TNF receptor-associated factor. (415 aa) |
| | PIK3R3 | LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa) |
| | LOC103088880 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa) |
| | TUBA1C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (414 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (350 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (536 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (325 aa) |
| | TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (416 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1. (523 aa) |
| | TUBA1A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (416 aa) |
| | CAPN2 | Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (656 aa) |
| | PRF1 | Perforin-1. (555 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa) |
| | CSF2RB | Cytokine receptor common subunit beta. (896 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa) |
| | HRK | Activator of apoptosis harakiri. (91 aa) |
| | LOC103086172 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | NGF | Beta-nerve growth factor; Belongs to the NGF-beta family. (241 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (341 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (959 aa) |
| | LOC103072956 | Uncharacterized protein LOC103072956. (225 aa) |
| | LMNA | prelamin-A/C isoform X1; Belongs to the intermediate filament family. (664 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (795 aa) |
| | ERN1 | LOW QUALITY PROTEIN: serine/threonine-protein kinase/endoribonuclease IRE1. (1251 aa) |
| | BBC3 | Bcl-2-binding component 3. (193 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (419 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) |
| | CASP9 | Caspase-9 isoform X1; Belongs to the peptidase C14A family. (452 aa) |
| | CTSC | Dipeptidyl peptidase 1 isoform X1; Belongs to the peptidase C1 family. (463 aa) |
| | CTSH | Pro-cathepsin H isoform X1; Belongs to the peptidase C1 family. (335 aa) |
| | LOC103073687 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa) |
| | LMNB2 | lamin-B2; Belongs to the intermediate filament family. (634 aa) |
| | DAXX | Death domain-associated protein 6. (757 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | FOS | Proto-oncogene c-Fos isoform X1. (380 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa) |
| | TNFRSF10A | Tumor necrosis factor receptor superfamily member 10A. (426 aa) |
| | CTSS | Cathepsin S isoform X1; Belongs to the peptidase C1 family. (340 aa) |
| | HTRA2 | Serine protease HTRA2, mitochondrial isoform X1. (458 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | RELA | Transcription factor p65 isoform X1. (560 aa) |
| | CAPN1 | Calpain-1 catalytic subunit isoform X1; Belongs to the peptidase C2 family. (716 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa) |
| | ACTG1 | Actin, cytoplasmic 2. (375 aa) |
| | CTSK | Cathepsin K; Belongs to the peptidase C1 family. (329 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa) |
| | JUN | Transcription factor AP-1; Belongs to the bZIP family. (337 aa) |
| | IL3RA | Interleukin-3 receptor subunit alpha. (385 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | LOC103075576 | Tumor necrosis factor receptor superfamily member 10A-like. (266 aa) |
| | LOC103069848 | Putative Bcl-2 homologous antagonist/killer 2-like. (211 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | IL3 | Interleukin-3. (144 aa) |
| | MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog isoform X1. (351 aa) |
| | BIRC5 | Baculoviral IAP repeat-containing protein 5. (142 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | CTSO | Cathepsin O; Belongs to the peptidase C1 family. (284 aa) |
| | LOC103079424 | LOW QUALITY PROTEIN: caspase-12-like; Belongs to the peptidase C14A family. (446 aa) |
| | CTSF | LOW QUALITY PROTEIN: cathepsin F; Belongs to the peptidase C1 family. (490 aa) |
| | CTSW | Cathepsin W; Belongs to the peptidase C1 family. (376 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa) |
| | BAD | Bcl2 antagonist of cell death. (168 aa) |
| | CASP6 | Caspase-6; Belongs to the peptidase C14A family. (275 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | PARP2 | Poly [ADP-ribose] polymerase. (591 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (232 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (304 aa) |
| | LMNB1 | lamin-B1; Belongs to the intermediate filament family. (586 aa) |
| | DFFA | DNAation factor subunit alpha. (331 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (530 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (288 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (977 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | CTSD | Cathepsin D isoform X1; Belongs to the peptidase A1 family. (412 aa) |
| | LOC103075495 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | CASP2 | Caspase-2; Belongs to the peptidase C14A family. (452 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | PIDD | P53-induced protein with a death domain. (913 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | PTPN13 | Tyrosine-protein phosphatase non-receptor type 13 isoform X2. (2493 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | DAB2IP | LOW QUALITY PROTEIN: disabled homolog 2-interacting protein. (1173 aa) |
| | LOC103083173 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CASP3 | Caspase-3; Belongs to the peptidase C14A family. (275 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1118 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (445 aa) |
| | CFLAR | CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (509 aa) |
| | BID | BH3-interacting domain death agonist. (297 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (342 aa) |
| | CASP7 | Caspase-7 isoform X1; Belongs to the peptidase C14A family. (301 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (456 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha. (747 aa) |
| | SPTAN1 | Spectrin alpha chain, non-erythrocytic 1 isoform X1. (2477 aa) |
| | ENDOG | Endonuclease. (296 aa) |
| | GZMB | Granzyme B; Belongs to the peptidase S1 family. (248 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa) |
| | LOC103088275 | LOW QUALITY PROTEIN: mast cell protease 3-like. (270 aa) |
| | CTSB | Cathepsin B; Belongs to the peptidase C1 family. (335 aa) |
