STRINGSTRING
SERPINA1 SERPINA1 BDKRB2 BDKRB2 BDKRB1 BDKRB1 SERPINA5 SERPINA5 PROCR PROCR VSIG4 VSIG4 MASP1 MASP1 FGA FGA FGB FGB ITGAX ITGAX LOC103068503 LOC103068503 KNG1 KNG1 SERPIND1 SERPIND1 C5 C5 F9 F9 VTN VTN ITGAM ITGAM ITGB2 ITGB2 LOC103089778 LOC103089778 F2 F2 SERPINF2 SERPINF2 PLAT PLAT SERPING1 SERPING1 PLAUR PLAUR C8G C8G C1QA C1QA C1QB C1QB CFB CFB LOC103085808 LOC103085808 LOC103073034 LOC103073034 C5AR1 C5AR1 THBD THBD F5 F5 C1QC C1QC C2 C2 F13B F13B C9 C9 C4A C4A CFD CFD LOC103074903 LOC103074903 C8A C8A C3 C3 F12 F12 PROS1 PROS1 MASP2 MASP2 PROC PROC F2RL3 F2RL3 F2R F2R C8B C8B F2RL2 F2RL2 LOC103087584 LOC103087584 SERPINB2 SERPINB2 CFI CFI F11 F11 CLU CLU F10 F10 CPB2 CPB2 CD59 CD59 F7 F7 F13A1 F13A1 F8 F8 PLAU PLAU VWF VWF C7 C7 F3 F3 LOC103077690 LOC103077690 C6 C6 MBL2 MBL2 SERPINE1 SERPINE1 C1R C1R LOC103087891 LOC103087891 C3AR1 C3AR1 C1S C1S CR2 CR2 C4BPB C4BPB SERPINC1 SERPINC1 CD55 CD55 TFPI TFPI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SERPINA1Alpha-1-antitrypsin isoform X1; Belongs to the serpin family. (422 aa)
BDKRB2B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (379 aa)
BDKRB1B1 bradykinin receptor. (352 aa)
SERPINA5Plasma serine protease inhibitor; Belongs to the serpin family. (404 aa)
PROCREndothelial protein C receptor. (242 aa)
VSIG4V-set and immunoglobulin domain-containing protein 4 isoform X1. (399 aa)
MASP1Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (728 aa)
FGAFibrinogen alpha chain. (605 aa)
FGBFibrinogen beta chain isoform X1. (488 aa)
ITGAXIntegrin alpha-X; Belongs to the integrin alpha chain family. (1160 aa)
LOC103068503LOW QUALITY PROTEIN: fibrinogen gamma-B chain-like. (445 aa)
KNG1Kininogen-1 isoform X1. (627 aa)
SERPIND1Heparin cofactor 2; Belongs to the serpin family. (496 aa)
C5LOW QUALITY PROTEIN: complement C5. (1677 aa)
F9Coagulation factor IX isoform X1. (462 aa)
VTNVitronectin isoform X1. (565 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (1152 aa)
ITGB2Integrin beta. (769 aa)
LOC103089778Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (350 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
SERPINF2Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (494 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
SERPING1Plasma protease C1 inhibitor; Belongs to the serpin family. (483 aa)
PLAURUrokinase plasminogen activator surface receptor. (334 aa)
C8GComplement component C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (320 aa)
C1QAComplement C1q subcomponent subunit A. (245 aa)
C1QBComplement C1q subcomponent subunit B. (252 aa)
CFBComplement factor B; Belongs to the peptidase S1 family. (765 aa)
LOC103085808Complement factor H-like. (1227 aa)
LOC103073034Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (814 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
THBDThrombomodulin. (584 aa)
F5LOW QUALITY PROTEIN: coagulation factor V; Belongs to the multicopper oxidase family. (2108 aa)
C1QCComplement C1q subcomponent subunit C. (245 aa)
C2Complement C2 isoform X1; Belongs to the peptidase S1 family. (751 aa)
F13BCoagulation factor XIII B chain. (660 aa)
C9Complement component C9. (548 aa)
C4AComplement C4-A. (1739 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (197 aa)
LOC103074903Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (386 aa)
C8AComplement component C8 alpha chain. (589 aa)
C3Complement C3. (1660 aa)
F12LOW QUALITY PROTEIN: coagulation factor XII. (628 aa)
PROS1Vitamin K-dependent protein S. (674 aa)
MASP2Mannan-binding lectin serine protease 2; Belongs to the peptidase S1 family. (686 aa)
PROCVitamin K-dependent protein C. (480 aa)
F2RL3Proteinase-activated receptor 4; Belongs to the G-protein coupled receptor 1 family. (379 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (428 aa)
C8BComplement component C8 beta chain. (586 aa)
F2RL2Proteinase-activated receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (378 aa)
LOC103087584Mannose-binding protein A-like. (249 aa)
SERPINB2Plasminogen activator inhibitor 2; Belongs to the serpin family. (416 aa)
CFILOW QUALITY PROTEIN: complement factor I; Belongs to the peptidase S1 family. (623 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (625 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (441 aa)
F10Coagulation factor X. (509 aa)
CPB2Carboxypeptidase B2 isoform X1. (423 aa)
CD59CD59 glycoprotein. (123 aa)
F7Coagulation factor VII. (387 aa)
F13A1Coagulation factor XIII A chain. (732 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2336 aa)
PLAUUrokinase-type plasminogen activator isoform X1. (440 aa)
VWFVon Willebrand factor. (2780 aa)
C7Complement component C7. (843 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (292 aa)
LOC103077690Alpha-2-macroglobulin-like. (1475 aa)
C6Complement component C6. (932 aa)
MBL2LOW QUALITY PROTEIN: mannose-binding protein C. (235 aa)
SERPINE1Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
C1RComplement C1r subcomponent; Belongs to the peptidase S1 family. (713 aa)
LOC103087891C4b-binding protein alpha chain-like. (665 aa)
C3AR1C3a anaphylatoxin chemotactic receptor; Belongs to the G-protein coupled receptor 1 family. (498 aa)
C1SLOW QUALITY PROTEIN: complement C1s subcomponent; Belongs to the peptidase S1 family. (793 aa)
CR2Complement receptor type 2 isoform X1. (1471 aa)
C4BPBC4b-binding protein beta chain. (198 aa)
SERPINC1antithrombin-III; Belongs to the serpin family. (465 aa)
CD55Complement decay-accelerating factor. (571 aa)
TFPITissue factor pathway inhibitor isoform X1. (307 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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