STRINGSTRING
INPP5D INPP5D MAPK8 MAPK8 SOS2 SOS2 KRAS KRAS SYK SYK LCP2 LCP2 SOS1 SOS1 ALOX5 ALOX5 LOC103081641 LOC103081641 VAV3 VAV3 MAP2K3 MAP2K3 ALOX5AP ALOX5AP MAP2K1 MAP2K1 LOC103083537 LOC103083537 RAC1 RAC1 MAPK1 MAPK1 FYN FYN PIK3R3 PIK3R3 VAV2 VAV2 PIK3CD PIK3CD PLA2G4A PLA2G4A MAPK11 MAPK11 PLCG2 PLCG2 MAPK3 MAPK3 LAT LAT PRKCA PRKCA PDPK1 PDPK1 MAPK12 MAPK12 RAC2 RAC2 LOC103075361 LOC103075361 GRB2 GRB2 PIK3R1 PIK3R1 AKT1 AKT1 MAP2K4 MAP2K4 GAB2 GAB2 LOC103075075 LOC103075075 AKT2 AKT2 PLA2G4F PLA2G4F MAP2K7 MAP2K7 TNF TNF IL13 IL13 PLA2G4B PLA2G4B MAP2K2 MAP2K2 PIK3R2 PIK3R2 PLA2G4D PLA2G4D FCER1A FCER1A PLA2G4E PLA2G4E AKT3 AKT3 VAV1 VAV1 IL4 IL4 IL3 IL3 RAF1 RAF1 CSF2 CSF2 IL5 IL5 MS4A2 MS4A2 NRAS NRAS RAC3 RAC3 PLCG1 PLCG1 LYN LYN MAPK9 MAPK9 MAPK10 MAPK10 PIK3CB PIK3CB PIK3CA PIK3CA MAPK14 MAPK14 MAPK13 MAPK13 HRAS HRAS FCER1G FCER1G BTK BTK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1187 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
SOS2Son of sevenless homolog 2-like. (1272 aa)
KRASGTPase KRas. (188 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
LCP2Lymphocyte cytosolic protein 2. (532 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
ALOX5Arachidonate 5-lipoxygenase isoform X1. (674 aa)
LOC103081641LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6-like; Belongs to the protein kinase superfamily. (394 aa)
VAV3Guanine nucleotide exchange factor VAV3 isoform X1. (875 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
ALOX5APArachidonate 5-lipoxygenase-activating protein. (114 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
LOC103083537Interleukin-13-like. (81 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (201 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
FYNTyrosine-protein kinase. (537 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (878 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
PLA2G4APhospholipase A2. (749 aa)
MAPK11Mitogen-activated protein kinase. (350 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
LATLinker for activation of T-cells family member 1. (260 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
LOC103075361Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like. (149 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (410 aa)
GAB2GRB2-associated-binding protein 2. (640 aa)
LOC103075075Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like. (149 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
PLA2G4FPhospholipase A2. (849 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
IL13Interleukin-13. (132 aa)
PLA2G4BPhospholipase A2. (780 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
PLA2G4DPhospholipase A2. (818 aa)
FCER1AHigh affinity immunoglobulin epsilon receptor subunit alpha. (262 aa)
PLA2G4EPhospholipase A2. (883 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
VAV1Proto-oncogene vav isoform X1. (844 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (133 aa)
IL3Interleukin-3. (144 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
MS4A2High affinity immunoglobulin epsilon receptor subunit beta. (243 aa)
NRASGTPase NRas. (189 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
LYNTyrosine-protein kinase. (516 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
HRASGTPase HRas isoform X1. (189 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (87 aa)
BTKTyrosine-protein kinase. (659 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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