STRINGSTRING
MAPK8 MAPK8 CAMK2B CAMK2B CALML4 CALML4 GNG2 GNG2 PPP1CC PPP1CC ITPR2 ITPR2 KIF5B KIF5B PPP2CB PPP2CB CACNA1D CACNA1D DDC DDC GNAS GNAS GSK3B GSK3B CAMK2A CAMK2A GRIA3 GRIA3 PRKCB PRKCB CALML6 CALML6 GNB1 GNB1 ADCY5 ADCY5 GNAI3 GNAI3 SCN1A SCN1A LOC103085385 LOC103085385 PPP2R5A PPP2R5A PLCB4 PLCB4 GNG10 GNG10 PPP1CA PPP1CA GNG11 GNG11 CALY CALY PLCB1 PLCB1 CLOCK CLOCK ATF2 ATF2 PPP3CC PPP3CC PPP2R2B PPP2R2B ATF4 ATF4 MAPK11 MAPK11 PPP2R2D PPP2R2D GNG4 GNG4 CAMK2D CAMK2D GRIN2B GRIN2B PRKCA PRKCA ITPR1 ITPR1 GRIA4 GRIA4 GNG13 GNG13 CREB3 CREB3 PPP3CB PPP3CB MAPK12 MAPK12 ARRB1 ARRB1 KIF5C KIF5C AKT1 AKT1 MAOB MAOB DRD3 DRD3 CREB3L1 CREB3L1 LOC103072956 LOC103072956 PPP2R5C PPP2R5C LOC103082213 LOC103082213 PPP2R5D PPP2R5D MAOA MAOA AKT2 AKT2 LOC103086084 LOC103086084 CACNA1B CACNA1B ARRB2 ARRB2 PRKACB PRKACB PPP2R3A PPP2R3A GNG8 GNG8 GNAQ GNAQ PPP2R5E PPP2R5E CREB3L4 CREB3L4 GRIA1 GRIA1 CALM3 CALM3 GSK3A GSK3A ATF6B ATF6B FOS FOS PRKCG PRKCG PLCB2 PLCB2 PPP2R3B PPP2R3B GRIA2 GRIA2 GNB5 GNB5 KCNJ9 KCNJ9 PLCB3 PLCB3 COMT COMT CREB3L3 CREB3L3 AKT3 AKT3 ITPR3 ITPR3 GNAL GNAL PPP2CA PPP2CA PPP3CA PPP3CA GNG3 GNG3 PPP2R5B PPP2R5B KCNJ5 KCNJ5 GRIN2A GRIN2A LOC103082698 LOC103082698 MAPK9 MAPK9 DRD1 DRD1 MAPK10 MAPK10 PPP2R2C PPP2R2C TH TH CREB5 CREB5 PPP2R2A PPP2R2A PPP1R1B PPP1R1B PPP2R1B PPP2R1B PPP2R3C PPP2R3C LOC103075492 LOC103075492 DRD4 DRD4 LOC103089724 LOC103089724 KCNJ3 KCNJ3 MAPK14 MAPK14 GNAI1 GNAI1 MAPK13 MAPK13 CREB3L2 CREB3L2 LOC103074541 LOC103074541 CALML5 CALML5 KIF5A KIF5A GNAI2 GNAI2 LOC103069500 LOC103069500 GNB2 GNB2 CAMK2G CAMK2G GNB4 GNB4 PRKACA PRKACA GNB3 GNB3 CACNA1C CACNA1C SLC18A2 SLC18A2 KCNJ6 KCNJ6 CREB1 CREB1 CACNA1A CACNA1A ARNTL ARNTL SLC18A1 SLC18A1 PPP1CB PPP1CB CALM1 CALM1 SLC6A3 SLC6A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK8Mitogen-activated protein kinase. (427 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
KIF5BKinesin-1 heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1001 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
DDCaromatic-L-amino-acid decarboxylase. (315 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (991 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
GRIA3Glutamate receptor 3 isoform X1. (888 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CALML6Calmodulin-like protein 6. (190 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1. (340 aa)
ADCY5Adenylate cyclase type 5 isoform X1. (1263 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
LOC103085385Neuroendocrine secretory protein 55-like. (242 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (469 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
CALYNeuron-specific vesicular protein calcyon. (228 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
CLOCKCircadian locomoter output cycles protein kaput isoform X1. (853 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
PPP3CCSerine/threonine-protein phosphatase. (583 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (545 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
MAPK11Mitogen-activated protein kinase. (350 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (449 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CAMK2DLOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type II subunit delta. (536 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1496 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
GRIA4Glutamate receptor 4 isoform X2. (902 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
CREB3Cyclic AMP-responsive element-binding protein 3 isoform X1. (376 aa)
PPP3CBSerine/threonine-protein phosphatase. (480 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
ARRB1Beta-arrestin-1. (418 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (955 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MAOBAmine oxidase. (520 aa)
DRD3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LOC103072956Uncharacterized protein LOC103072956. (225 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
LOC103082213Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like isoform X1. (589 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
MAOAAmine oxidase. (527 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
LOC103086084LOW QUALITY PROTEIN: serine/threonine-protein phosphatase PP1-gamma catalytic subunit B-like. (375 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2261 aa)
ARRB2Beta-arrestin-2 isoform X1. (421 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta. (274 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1150 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (80 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (426 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (709 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (579 aa)
GRIA2Glutamate receptor 2 isoform X1. (940 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (395 aa)
KCNJ9LOW QUALITY PROTEIN: G protein-activated inward rectifier potassium channel 3. (469 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (271 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X2. (458 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
GNALGuanine nucleotide-binding protein G(Olf) subunit alpha isoform X1. (380 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4 isoform X1. (419 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
LOC103082698Transmembrane O-methyltransferase-like. (258 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
THTyrosine 3-monooxygenase. (492 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
PPP1R1BProtein phosphatase 1 regulatory subunit 1B. (202 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1. (644 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (453 aa)
LOC103075492Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
DRD4LOW QUALITY PROTEIN: D(4) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa)
LOC103089724Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
LOC103074541LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
CALML5Calmodulin-like protein 5. (140 aa)
KIF5AKinesin heavy chain isoform 5A isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
GNAI2LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I) subunit alpha-2. (360 aa)
LOC103069500Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (672 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2112 aa)
SLC18A2Synaptic vesicular amine transporter. (517 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (423 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (293 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2295 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X3. (632 aa)
SLC18A1Chromaffin granule amine transporter. (523 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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