STRINGSTRING
LOC103083349 LOC103083349 ADCY2 ADCY2 LOC103079978 LOC103079978 LOC103068564 LOC103068564 ADCY1 ADCY1 LOC103071513 LOC103071513 ALOX5 ALOX5 SCARB1 SCARB1 ADCY4 ADCY4 GNAS GNAS ADCY8 ADCY8 STAR STAR PTGS2 PTGS2 ADCY5 ADCY5 LOC103085385 LOC103085385 LOC103071815 LOC103071815 HSD17B1 HSD17B1 ADCY6 ADCY6 PLA2G4A PLA2G4A BMP15 BMP15 IGF1 IGF1 HSD17B2 HSD17B2 ADCY9 ADCY9 ADCY3 ADCY3 LOC103081312 LOC103081312 LOC103080853 LOC103080853 HSD17B7 HSD17B7 LOC103083046 LOC103083046 PRKACB PRKACB PLA2G4F PLA2G4F INSR INSR ACOT2 ACOT2 PLA2G4B PLA2G4B ADCY7 ADCY7 ACOT4 ACOT4 PLA2G4D PLA2G4D LHCGR LHCGR PLA2G4E PLA2G4E LDLR LDLR LOC103074712 LOC103074712 LOC103072875 LOC103072875 LHB LHB BMP6 BMP6 LOC103069218 LOC103069218 INS INS CGA CGA PRKACA PRKACA IGF1R IGF1R LOC103081477 LOC103081477
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103083349Cytochrome P450 1B1-like; Belongs to the cytochrome P450 family. (543 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
LOC103079978Acyl-coenzyme A thioesterase 4-like. (207 aa)
LOC103068564Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
LOC103071513Cytochrome P450 1A1-like; Belongs to the cytochrome P450 family. (516 aa)
ALOX5Arachidonate 5-lipoxygenase isoform X1. (674 aa)
SCARB1Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (509 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (991 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
PTGS2Prostaglandin G/H synthase 2 isoform X2. (604 aa)
ADCY5Adenylate cyclase type 5 isoform X1. (1263 aa)
LOC103085385Neuroendocrine secretory protein 55-like. (242 aa)
LOC103071815Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
HSD17B1Estradiol 17-beta-dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
PLA2G4APhospholipase A2. (749 aa)
BMP15Bone morphogenetic protein 15. (403 aa)
IGF1Insulin-like growth factor I isoform X1. (174 aa)
HSD17B2Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (388 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1141 aa)
LOC103081312Aromatase-like; Belongs to the cytochrome P450 family. (503 aa)
LOC103080853Aromatase-like isoform X1; Belongs to the cytochrome P450 family. (503 aa)
HSD17B73-keto-steroid reductase. (334 aa)
LOC1030830463 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like; Belongs to the 3-beta-HSD family. (373 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta. (274 aa)
PLA2G4FPhospholipase A2. (849 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
ACOT2Acyl-coenzyme A thioesterase 2, mitochondrial isoform X1. (464 aa)
PLA2G4BPhospholipase A2. (780 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
ACOT4LOW QUALITY PROTEIN: acyl-coenzyme A thioesterase 4. (339 aa)
PLA2G4DPhospholipase A2. (818 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (700 aa)
PLA2G4EPhospholipase A2. (883 aa)
LDLRLow-density lipoprotein receptor. (857 aa)
LOC103074712Follitropin subunit beta-like. (129 aa)
LOC103072875Cytochrome P450 2J2-like; Belongs to the cytochrome P450 family. (509 aa)
LHBLutropin subunit beta. (141 aa)
BMP6Bone morphogenetic protein 6. (495 aa)
LOC103069218Dihydrodiol dehydrogenase 3-like. (323 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
LOC103081477Steroid 17-alpha-hydroxylase/17,20 lyase-like; Belongs to the cytochrome P450 family. (509 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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