49 items (Lipotes vexillifer) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103083349	Cytochrome P450 1B1-like; Belongs to the cytochrome P450 family. (543 aa)
	ADCY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
	LOC103079978	Acyl-coenzyme A thioesterase 4-like. (207 aa)
	LOC103068564	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
	ADCY1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
	LOC103071513	Cytochrome P450 1A1-like; Belongs to the cytochrome P450 family. (516 aa)
	ALOX5	Arachidonate 5-lipoxygenase isoform X1. (674 aa)
	SCARB1	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (509 aa)
	ADCY4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	GNAS	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (991 aa)
	ADCY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
	PTGS2	Prostaglandin G/H synthase 2 isoform X2. (604 aa)
	ADCY5	Adenylate cyclase type 5 isoform X1. (1263 aa)
	LOC103085385	Neuroendocrine secretory protein 55-like. (242 aa)
	LOC103071815	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
	HSD17B1	Estradiol 17-beta-dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	PLA2G4A	Phospholipase A2. (749 aa)
	BMP15	Bone morphogenetic protein 15. (403 aa)
	IGF1	Insulin-like growth factor I isoform X1. (174 aa)
	HSD17B2	Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (388 aa)
	ADCY9	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	ADCY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1141 aa)
	LOC103081312	Aromatase-like; Belongs to the cytochrome P450 family. (503 aa)
	LOC103080853	Aromatase-like isoform X1; Belongs to the cytochrome P450 family. (503 aa)
	HSD17B7	3-keto-steroid reductase. (334 aa)
	LOC103083046	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like; Belongs to the 3-beta-HSD family. (373 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta. (274 aa)
	PLA2G4F	Phospholipase A2. (849 aa)
	INSR	Tyrosine-protein kinase receptor. (1382 aa)
	ACOT2	Acyl-coenzyme A thioesterase 2, mitochondrial isoform X1. (464 aa)
	PLA2G4B	Phospholipase A2. (780 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
	ACOT4	LOW QUALITY PROTEIN: acyl-coenzyme A thioesterase 4. (339 aa)
	PLA2G4D	Phospholipase A2. (818 aa)
	LHCGR	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (700 aa)
	PLA2G4E	Phospholipase A2. (883 aa)
	LDLR	Low-density lipoprotein receptor. (857 aa)
	LOC103074712	Follitropin subunit beta-like. (129 aa)
	LOC103072875	Cytochrome P450 2J2-like; Belongs to the cytochrome P450 family. (509 aa)
	LHB	Lutropin subunit beta. (141 aa)
	BMP6	Bone morphogenetic protein 6. (495 aa)
	LOC103069218	Dihydrodiol dehydrogenase 3-like. (323 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	CGA	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	LOC103081477	Steroid 17-alpha-hydroxylase/17,20 lyase-like; Belongs to the cytochrome P450 family. (509 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOT2	ACOT4	A0A340XI67	A0A340XKQ5	Acyl-coenzyme A thioesterase 2, mitochondrial isoform X1.	LOW QUALITY PROTEIN: acyl-coenzyme A thioesterase 4.	0.906
ACOT2	LOC103079978	A0A340XI67	A0A340WG21	Acyl-coenzyme A thioesterase 2, mitochondrial isoform X1.	Acyl-coenzyme A thioesterase 4-like.	0.907
ACOT4	ACOT2	A0A340XKQ5	A0A340XI67	LOW QUALITY PROTEIN: acyl-coenzyme A thioesterase 4.	Acyl-coenzyme A thioesterase 2, mitochondrial isoform X1.	0.906
ACOT4	LOC103079978	A0A340XKQ5	A0A340WG21	LOW QUALITY PROTEIN: acyl-coenzyme A thioesterase 4.	Acyl-coenzyme A thioesterase 4-like.	0.900
ADCY1	ADCY2	A0A340WHT5	A0A340WEH1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.546
ADCY1	ADCY3	A0A340WHT5	A0A340X1W5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.940
ADCY1	ADCY4	A0A340WHT5	A0A340WK40	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.540
ADCY1	ADCY5	A0A340WHT5	A0A340WQ40	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5 isoform X1.	0.524
ADCY1	ADCY6	A0A340WHT5	A0A340WTP8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.523
ADCY1	ADCY7	A0A340WHT5	A0A340XKH5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.638
ADCY1	ADCY8	A0A340WHT5	A0A340WM11	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.953
ADCY1	ADCY9	A0A340WHT5	A0A340X0V2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.633
ADCY1	GNAS	A0A340WHT5	A0A340WLE5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like.	0.961
ADCY1	LOC103085385	A0A340WHT5	A0A340WRC9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Neuroendocrine secretory protein 55-like.	0.900
ADCY1	PRKACA	A0A340WHT5	A0A340Y602	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.925
ADCY1	PRKACB	A0A340WHT5	A0A340XE43	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta.	0.928
ADCY2	ADCY1	A0A340WEH1	A0A340WHT5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.546
ADCY2	ADCY4	A0A340WEH1	A0A340WK40	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.520
ADCY2	ADCY5	A0A340WEH1	A0A340WQ40	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5 isoform X1.	0.992
ADCY2	ADCY6	A0A340WEH1	A0A340WTP8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.774