120 items (Lipotes vexillifer) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103075485	Progesterone receptor-like isoform X1. (936 aa)
	SOS2	Son of sevenless homolog 2-like. (1272 aa)
	SHC3	SHC-transforming protein 3. (588 aa)
	NCOA3	Nuclear receptor coactivator. (1462 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
	KRAS	GTPase KRas. (188 aa)
	SRC	Tyrosine-protein kinase. (548 aa)
	ADCY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
	CALML4	LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
	SOS1	Son of sevenless homolog 1. (1333 aa)
	NCOA2	Nuclear receptor coactivator. (1464 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
	ADCY1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
	KRT18	Keratin, type I cytoskeletal 18-like; Belongs to the intermediate filament family. (429 aa)
	ADCY4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	GNAS	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (991 aa)
	ADCY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
	LOC103073174	Heat shock cognate 90 kDa protein-like. (634 aa)
	MAPK1	Mitogen-activated protein kinase 1 isoform X1. (263 aa)
	CALML6	Calmodulin-like protein 6. (190 aa)
	ADCY5	Adenylate cyclase type 5 isoform X1. (1263 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1. (963 aa)
	GNAI3	Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
	LOC103085385	Neuroendocrine secretory protein 55-like. (242 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
	MMP9	Matrix metalloproteinase-9. (708 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	GRM1	Metabotropic glutamate receptor 1 isoform X1. (1194 aa)
	PIK3R3	LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
	ATF4	Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
	MAPK3	Mitogen-activated protein kinase. (325 aa)
	HSP90B1	Endoplasmin. (803 aa)
	TGFA	Protransforming growth factor alpha. (145 aa)
	ADCY9	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	NCOA1	Nuclear receptor coactivator. (1440 aa)
	ADCY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1141 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
	SHC4	SHC-transforming protein 4 isoform X1. (631 aa)
	HSP90AA1	Heat shock protein HSP 90-alpha. (732 aa)
	CREB3	Cyclic AMP-responsive element-binding protein 3 isoform X1. (376 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	POMC	Pro-opiomelanocortin. (261 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	CREB3L1	Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
	LOC103072956	Uncharacterized protein LOC103072956. (225 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (584 aa)
	OPRM1	Mu-type opioid receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (479 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	HSPA1L	LOW QUALITY PROTEIN: heat shock 70 kDa protein 1-like; Belongs to the heat shock protein 70 family. (634 aa)
	HSP90AB1	Heat shock protein HSP 90-beta isoform X1. (724 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta. (274 aa)
	GNAQ	Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
	CREB3L4	Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (426 aa)
	CALM3	Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
	MMP2	72 kDa type IV collagenase. (584 aa)
	ATF6B	Cyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (709 aa)
	FOS	Proto-oncogene c-Fos isoform X1. (380 aa)
	ESR2	Estrogen receptor beta. (533 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
	LOC103073518	Heat shock 70 kDa protein 1B-like; Belongs to the heat shock protein 70 family. (641 aa)
	SHC2	SHC-transforming protein 2. (801 aa)
	MAP2K2	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
	KCNJ9	LOW QUALITY PROTEIN: G protein-activated inward rectifier potassium channel 3. (469 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
	JUN	Transcription factor AP-1; Belongs to the bZIP family. (337 aa)
	CREB3L3	Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X2. (458 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC103071041	Heat shock-related 70 kDa protein 2-like; Belongs to the heat shock protein 70 family. (638 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	RAF1	RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
	EGFR	Receptor protein-tyrosine kinase. (1209 aa)
	GABBR2	Gamma-aminobutyric acid type B receptor subunit 2. (940 aa)
	NRAS	GTPase NRas. (189 aa)
	KCNJ5	G protein-activated inward rectifier potassium channel 4 isoform X1. (419 aa)
	BCL2	Apoptosis regulator Bcl-2. (232 aa)
	LOC103074911	Heat shock cognate 90 kDa protein-like. (518 aa)
	LOC103087122	Keratin, type I cuticular Ha1-like; Belongs to the intermediate filament family. (416 aa)
	KRT17	Keratin, type I cytoskeletal 17; Belongs to the intermediate filament family. (430 aa)
	KRT36	LOW QUALITY PROTEIN: keratin, type I cuticular Ha6; Belongs to the intermediate filament family. (456 aa)
	KRT15	LOW QUALITY PROTEIN: keratin, type I cytoskeletal 15; Belongs to the intermediate filament family. (447 aa)
	CREB5	Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
	CTSD	Cathepsin D isoform X1; Belongs to the peptidase A1 family. (412 aa)
	RARA	Retinoic acid receptor alpha isoform X1. (462 aa)
	KRT13	Keratin, type I cytoskeletal 13; Belongs to the intermediate filament family. (416 aa)
	LOC103074638	LOW QUALITY PROTEIN: keratin, type I cytoskeletal 42-like; Belongs to the intermediate filament family. (437 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
	GPER1	G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	KCNJ3	G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
	KRT19	Keratin, type I cytoskeletal 19; Belongs to the intermediate filament family. (400 aa)
	FKBP5	Peptidylprolyl isomerase. (457 aa)
	GNAI1	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
	KRT24	LOW QUALITY PROTEIN: keratin, type I cytoskeletal 24; Belongs to the intermediate filament family. (508 aa)
	KRT14	Keratin, type I cytoskeletal 14; Belongs to the intermediate filament family. (474 aa)
	KRT35	LOW QUALITY PROTEIN: keratin, type I cuticular Ha5; Belongs to the intermediate filament family. (451 aa)
	CREB3L2	Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
	LOC103074541	LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
	CALML5	Calmodulin-like protein 5. (140 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	GNAI2	LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I) subunit alpha-2. (360 aa)
	EBAG9	Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (213 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	FKBP4	Peptidylprolyl isomerase. (458 aa)
	KCNJ6	G protein-activated inward rectifier potassium channel 2. (423 aa)
	LOC103074840	Heat shock cognate 71 kDa protein-like; Belongs to the heat shock protein 70 family. (634 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1. (293 aa)
	KRT16	LOW QUALITY PROTEIN: keratin 16; Belongs to the intermediate filament family. (320 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
	HSPA8	LOW QUALITY PROTEIN: heat shock 70kDa protein 8; Belongs to the heat shock protein 70 family. (650 aa)
	CALM1	Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
	KRT32	LOW QUALITY PROTEIN: keratin 32; Belongs to the intermediate filament family. (327 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	A0A340WHT5	A0A340WEH1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.546
ADCY1	ADCY3	A0A340WHT5	A0A340X1W5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.940
ADCY1	ADCY4	A0A340WHT5	A0A340WK40	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.540
ADCY1	ADCY5	A0A340WHT5	A0A340WQ40	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5 isoform X1.	0.524
ADCY1	ADCY6	A0A340WHT5	A0A340WTP8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.523
ADCY1	ADCY7	A0A340WHT5	A0A340XKH5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.638
ADCY1	ADCY8	A0A340WHT5	A0A340WM11	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.953
ADCY1	ADCY9	A0A340WHT5	A0A340X0V2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.633
ADCY1	AKT1	A0A340WHT5	A0A340X6L4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.687
ADCY1	AKT2	A0A340WHT5	A0A340XBA5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.687
ADCY1	AKT3	A0A340WHT5	A0A340XMT5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.687
ADCY1	ATF4	A0A340WHT5	A0A340WXH5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Cyclic AMP-dependent transcription factor ATF-4.	0.495
ADCY1	CALM1	A0A340WHT5	A0A340YIN4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin isoform X1; Belongs to the calmodulin family.	0.930
ADCY1	CALM3	A0A340WHT5	A0A340XH15	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin isoform X2; Belongs to the calmodulin family.	0.930
ADCY1	CALML4	A0A340WHT5	A0A340WF41	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	LOW QUALITY PROTEIN: calmodulin-like protein 4.	0.927
ADCY1	CALML5	A0A340WHT5	A0A340Y368	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like protein 5.	0.940
ADCY1	CALML6	A0A340WHT5	A0A340WPN5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like protein 6.	0.928
ADCY1	GNAI1	A0A340WHT5	A0A340Y197	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1.	0.824
ADCY1	GNAI2	A0A340WHT5	A0A340Y3S9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I) subunit alpha-2.	0.797
ADCY1	GNAI3	A0A340WHT5	A0A340WQY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.797