STRINGSTRING
FZD8 FZD8 WNT10A WNT10A CAMK2B CAMK2B KRAS KRAS WNT6 WNT6 ADCY2 ADCY2 CALML4 CALML4 EDN1 EDN1 ASIP ASIP FZD4 FZD4 ADCY1 ADCY1 MITF MITF DVL1 DVL1 ADCY4 ADCY4 WNT7A WNT7A GNAS GNAS ADCY8 ADCY8 GSK3B GSK3B MAP2K1 MAP2K1 CAMK2A CAMK2A PRKCB PRKCB MAPK1 MAPK1 CALML6 CALML6 KITLG KITLG ADCY5 ADCY5 GNAI3 GNAI3 LOC103085385 LOC103085385 PLCB4 PLCB4 PLCB1 PLCB1 ADCY6 ADCY6 WNT1 WNT1 WNT2 WNT2 CREBBP CREBBP FZD1 FZD1 EP300 EP300 MAPK3 MAPK3 LEF1 LEF1 WNT10B WNT10B CAMK2D CAMK2D ADCY9 ADCY9 PRKCA PRKCA ADCY3 ADCY3 CREB3 CREB3 WNT7B WNT7B DCT DCT LOC103076632 LOC103076632 WNT3A WNT3A POMC POMC CREB3L1 CREB3L1 WNT5A WNT5A KIT KIT WNT9A WNT9A PRKACB PRKACB LOC103090680 LOC103090680 GNAQ GNAQ DVL2 DVL2 CREB3L4 CREB3L4 WNT2B WNT2B WNT4 WNT4 CALM3 CALM3 WNT16 WNT16 PRKCG PRKCG PLCB2 PLCB2 WNT11 WNT11 MAP2K2 MAP2K2 ADCY7 ADCY7 PLCB3 PLCB3 CREB3L3 CREB3L3 TCF7 TCF7 WNT8A WNT8A RAF1 RAF1 FZD5 FZD5 LOC103083618 LOC103083618 NRAS NRAS FZD6 FZD6 TYRP1 TYRP1 FZD3 FZD3 CTNNB1 CTNNB1 WNT9B WNT9B GNAI1 GNAI1 WNT3 WNT3 CREB3L2 CREB3L2 LOC103074541 LOC103074541 EDNRB EDNRB CALML5 CALML5 HRAS HRAS GNAI2 GNAI2 CAMK2G CAMK2G PRKACA PRKACA FZD7 FZD7 FZD9 FZD9 TCF7L2 TCF7L2 WNT5B WNT5B DVL3 DVL3 WNT8B WNT8B CREB1 CREB1 FZD10 FZD10 TCF7L1 TCF7L1 CALM1 CALM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FZD8LOW QUALITY PROTEIN: frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (672 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa)
KRASGTPase KRas. (188 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
EDN1Endothelin-1. (202 aa)
ASIPAgouti-signaling protein. (133 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
MITFMicrophthalmia-associated transcription factor isoform X1. (520 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X2. (699 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (991 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
CALML6Calmodulin-like protein 6. (190 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
ADCY5Adenylate cyclase type 5 isoform X1. (1263 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC103085385Neuroendocrine secretory protein 55-like. (242 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
CREBBPCREB-binding protein isoform X1. (2429 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (644 aa)
EP300Histone acetyltransferase p300. (2420 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
CAMK2DLOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type II subunit delta. (536 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1141 aa)
CREB3Cyclic AMP-responsive element-binding protein 3 isoform X1. (376 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
DCTL-dopachrome tautomerase isoform X1. (519 aa)
LOC103076632Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
POMCPro-opiomelanocortin. (261 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta. (274 aa)
LOC103090680Tyrosinase-like. (297 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (734 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (426 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X2. (458 aa)
TCF7Transcription factor 7. (252 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa)
LOC103083618Tyrosinase-like. (261 aa)
NRASGTPase NRas. (189 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
TYRP15,6-dihydroxyindole-2-carboxylic acid oxidase. (537 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
LOC103074541LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
EDNRBEndothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
CALML5Calmodulin-like protein 5. (140 aa)
HRASGTPase HRas isoform X1. (189 aa)
GNAI2LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I) subunit alpha-2. (360 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (672 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (545 aa)
TCF7L2Transcription factor 7-like 2. (584 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (293 aa)
FZD10LOW QUALITY PROTEIN: frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (563 aa)
TCF7L1Transcription factor 7-like 1. (713 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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