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PAX8 PAX8 ADCY2 ADCY2 ATP1B3 ATP1B3 LOC103078794 LOC103078794 GSR GSR ITPR2 ITPR2 ADCY1 ADCY1 GPX5 GPX5 ADCY4 ADCY4 GNAS GNAS TG TG GPX3 GPX3 ADCY8 ADCY8 PRKCB PRKCB ADCY5 ADCY5 GPX6 GPX6 LOC103085385 LOC103085385 PLCB4 PLCB4 LRP2 LRP2 ATP1A1 ATP1A1 PLCB1 PLCB1 ADCY6 ADCY6 LOC103076881 LOC103076881 ATF2 ATF2 TTF1 TTF1 ATF4 ATF4 HSP90B1 HSP90B1 ADCY9 ADCY9 PRKCA PRKCA SLC26A4 SLC26A4 ADCY3 ADCY3 ITPR1 ITPR1 CREB3 CREB3 TSHB TSHB GPX7 GPX7 CREB3L1 CREB3L1 LOC103077185 LOC103077185 TTR TTR ASGR2 ASGR2 ATP1B2 ATP1B2 IYD IYD LOC103086733 LOC103086733 PRKACB PRKACB GNAQ GNAQ ATP1A4 ATP1A4 ASGR1 ASGR1 CREB3L4 CREB3L4 ATP1B1 ATP1B1 ATP1A3 ATP1A3 ATF6B ATF6B PRKCG PRKCG PLCB2 PLCB2 ADCY7 ADCY7 ATP1A2 ATP1A2 PLCB3 PLCB3 SERPINA7 SERPINA7 CREB3L3 CREB3L3 TTF2 TTF2 SLC5A5 SLC5A5 ITPR3 ITPR3 LOC103069578 LOC103069578 CREB5 CREB5 ATP1B4 ATP1B4 CANX CANX DUOX1 DUOX1 CREB3L2 CREB3L2 DUOXA2 DUOXA2 CGA CGA PRKACA PRKACA DUOX2 DUOX2 LOC103082367 LOC103082367 ALB ALB TPO TPO CREB1 CREB1 GPX8 GPX8 PDIA4 PDIA4 HSPA5 HSPA5 TSHR TSHR GPX1 GPX1 GPX2 GPX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAX8Paired box protein Pax-8. (288 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
LOC103078794Glutathione peroxidase; Belongs to the glutathione peroxidase family. (198 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (519 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (991 aa)
TGThyroglobulin. (2770 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (226 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ADCY5Adenylate cyclase type 5 isoform X1. (1263 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
LOC103085385Neuroendocrine secretory protein 55-like. (242 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4672 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (919 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC103076881Glutathione peroxidase; Belongs to the glutathione peroxidase family. (167 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
TTF1Transcription termination factor 1. (762 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
HSP90B1Endoplasmin. (803 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1141 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
CREB3Cyclic AMP-responsive element-binding protein 3 isoform X1. (376 aa)
TSHBThyrotropin subunit beta. (138 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
LOC103077185Glutathione peroxidase; Belongs to the glutathione peroxidase family. (160 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
ASGR2Asialoglycoprotein receptor 2. (302 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (294 aa)
IYDIodotyrosine dehalogenase 1. (289 aa)
LOC103086733Glutathione peroxidase; Belongs to the glutathione peroxidase family. (180 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta. (274 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (994 aa)
ASGR1Asialoglycoprotein receptor 1 isoform X1. (286 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (426 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (983 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (709 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
SERPINA7Thyroxine-binding globulin; Belongs to the serpin family. (420 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X2. (458 aa)
TTF2Transcription termination factor 2. (1165 aa)
SLC5A5Sodium/iodide cotransporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (642 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
LOC103069578Glutathione peroxidase; Belongs to the glutathione peroxidase family. (153 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (348 aa)
CANXCalnexin isoform X1. (593 aa)
DUOX1LOW QUALITY PROTEIN: dual oxidase 1. (1549 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
DUOXA2Dual oxidase maturation factor 2. (320 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
DUOX2Dual oxidase 2 isoform X1. (1553 aa)
LOC103082367Glutathione peroxidase; Belongs to the glutathione peroxidase family. (161 aa)
ALBSerum albumin. (607 aa)
TPOThyroid peroxidase isoform X1. (870 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (293 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
PDIA4Protein disulfide-isomerase. (646 aa)
HSPA578 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family. (655 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (206 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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