STRINGSTRING
CAMK2B CAMK2B ADCY2 ADCY2 CALML4 CALML4 ACACB ACACB LOC103079343 LOC103079343 PRKAG3 PRKAG3 PRKAB2 PRKAB2 ITPR2 ITPR2 FBP1 FBP1 PYGL PYGL GCK GCK LOC103073178 LOC103073178 LDHB LDHB GNAS GNAS PCK2 PCK2 CAMK2A CAMK2A PPARGC1A PPARGC1A FBP2 FBP2 CALML6 CALML6 GYS2 GYS2 PCK1 PCK1 LOC103085385 LOC103085385 PLCB4 PLCB4 PRKAG1 PRKAG1 G6PC G6PC PHKB PHKB PLCB1 PLCB1 ATF2 ATF2 PFKL PFKL PPP3CC PPP3CC CREBBP CREBBP SIK1 SIK1 PPARA PPARA ATF4 ATF4 CPT1B CPT1B EP300 EP300 G6PC2 G6PC2 PHKG1 PHKG1 PPP4C PPP4C SLC2A1 SLC2A1 CAMK2D CAMK2D PHKG2 PHKG2 G6PC3 G6PC3 ITPR1 ITPR1 CREB3 CREB3 PPP3CB PPP3CB PGAM1 PGAM1 PPP3R2 PPP3R2 AKT1 AKT1 CREB3L1 CREB3L1 CRTC2 CRTC2 AKT2 AKT2 SIRT1 SIRT1 PRKACB PRKACB GNAQ GNAQ CREB3L4 CREB3L4 CALM3 CALM3 PFKFB1 PFKFB1 PLCB2 PLCB2 PYGM PYGM PLCB3 PLCB3 GCGR GCGR PDE3B PDE3B CREB3L3 CREB3L3 AKT3 AKT3 ITPR3 ITPR3 PRMT1 PRMT1 CPT1C CPT1C GYS1 GYS1 PPP3CA PPP3CA PPP3R1 PPP3R1 SLC2A2 SLC2A2 SIK2 SIK2 PRKAA2 PRKAA2 PRKAB1 PRKAB1 ACACA ACACA SMEK2 SMEK2 PGAM2 PGAM2 PFKP PFKP LDHA LDHA CPT1A CPT1A CREB5 CREB5 GCG GCG CREB3L2 CREB3L2 LDHC LDHC PHKA1 PHKA1 LOC103074541 LOC103074541 CALML5 CALML5 PKM PKM PFKM PFKM CAMK2G CAMK2G PRKACA PRKACA PDHB PDHB PRKAG2 PRKAG2 PDHA1 PDHA1 PHKA2 PHKA2 CREB1 CREB1 SMEK1 SMEK1 PRKAA1 PRKAA1 FOXO1 FOXO1 CALM1 CALM1 PYGB PYGB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
ACACBacetyl-CoA carboxylase 2. (2457 aa)
LOC103079343Fructose-1,6-bisphosphatase, chloroplastic-like; Belongs to the FBPase class 1 family. (336 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3 isoform X3. (482 aa)
PRKAB25'-AMP-activated protein kinase subunit beta-2. (272 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
FBP1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa)
GCKPhosphotransferase. (466 aa)
LOC103073178Fructose-1,6-bisphosphatase, cytosolic-like; Belongs to the FBPase class 1 family. (281 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (991 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (640 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (796 aa)
FBP2Fructose-1,6-bisphosphatase isozyme 2; Belongs to the FBPase class 1 family. (305 aa)
CALML6Calmodulin-like protein 6. (190 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (701 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
LOC103085385Neuroendocrine secretory protein 55-like. (242 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X2. (336 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (972 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (781 aa)
PPP3CCSerine/threonine-protein phosphatase. (583 aa)
CREBBPCREB-binding protein isoform X1. (2429 aa)
SIK1Serine/threonine-protein kinase SIK1. (784 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
EP300Histone acetyltransferase p300. (2420 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
PHKG1Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Belongs to the protein kinase superfamily. (387 aa)
PPP4CSerine/threonine-protein phosphatase. (307 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1-like; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
CAMK2DLOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type II subunit delta. (536 aa)
PHKG2Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; Belongs to the protein kinase superfamily. (406 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
CREB3Cyclic AMP-responsive element-binding protein 3 isoform X1. (376 aa)
PPP3CBSerine/threonine-protein phosphatase. (480 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
PPP3R2LOW QUALITY PROTEIN: calcineurin subunit B type 2. (170 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
CRTC2CREB-regulated transcription coactivator 2. (692 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
SIRT1LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1. (695 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta. (274 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (426 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1 isoform X1. (471 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (479 aa)
PDE3BPhosphodiesterase. (1121 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X2. (458 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
CPT1CCarnitine O-palmitoyltransferase 1, brain isoform; Belongs to the carnitine/choline acetyltransferase family. (801 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (738 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PPP3R1Calcineurin subunit B type 1. (160 aa)
SLC2A2Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
SIK2Serine/threonine-protein kinase SIK2. (906 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (270 aa)
ACACAacetyl-CoA carboxylase 1 isoform X2. (2383 aa)
SMEK2Serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1. (820 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
CPT1ACarnitine O-palmitoyltransferase 1, liver isoform isoform X2; Belongs to the carnitine/choline acetyltransferase family. (774 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
GCGGlucagon isoform X1. (180 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
LDHCL-lactate dehydrogenase C chain. (167 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1240 aa)
LOC103074541LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
CALML5Calmodulin-like protein 5. (140 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (853 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (672 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (569 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1240 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (293 aa)
SMEK1Serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1. (833 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
FOXO1Forkhead box protein O1. (655 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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