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EDN2 EDN2 AGTR1 AGTR1 PTGER2 PTGER2 CALML4 CALML4 EDN1 EDN1 ADRB2 ADRB2 ORAI1 ORAI1 ITPR2 ITPR2 ADORA1 ADORA1 EDN3 EDN3 CACNA1D CACNA1D PRKG2 PRKG2 ADRB3 ADRB3 GNAS GNAS AGT AGT CALML6 CALML6 ADCY5 ADCY5 GNAI3 GNAI3 LOC103085385 LOC103085385 PLCB4 PLCB4 PLCB1 PLCB1 ADCY6 ADCY6 PPP3CC PPP3CC CACNA1F CACNA1F ITPR1 ITPR1 CACNA1S CACNA1S PDE3A PDE3A PPP3CB PPP3CB PPP3R2 PPP3R2 KCNJ2 KCNJ2 GUCY1A2 GUCY1A2 ADCYAP1 ADCYAP1 LOC103087287 LOC103087287 CLCA2 CLCA2 PRKACB PRKACB GNAQ GNAQ NPR1 NPR1 CALM3 CALM3 PDE1A PDE1A PLCB2 PLCB2 LOC103075302 LOC103075302 PLCB3 PLCB3 PDE3B PDE3B GUCY1B3 GUCY1B3 ITPR3 ITPR3 CLCA4 CLCA4 PPP3CA PPP3CA PPP3R1 PPP3R1 LOC103089557 LOC103089557 NPPA NPPA ADCYAP1R1 ADCYAP1R1 GNAI1 GNAI1 LOC103074541 LOC103074541 CALML5 CALML5 AQP1 AQP1 PDE1C PDE1C GNAI2 GNAI2 PRKACA PRKACA PDE1B PDE1B CACNA1C CACNA1C LOC103072349 LOC103072349 ADRB1 ADRB1 PTGER4 PTGER4 CREB1 CREB1 REN REN CTSB CTSB CALM1 CALM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDN2Endothelin-2. (180 aa)
AGTR1Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
PTGER2LOW QUALITY PROTEIN: prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (358 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
EDN1Endothelin-1. (202 aa)
ADRB2Beta-2 adrenergic receptor. (419 aa)
ORAI1Calcium release-activated calcium channel protein 1. (303 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
EDN3Endothelin-3. (211 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
ADRB3LOW QUALITY PROTEIN: beta-3 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (375 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (991 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
CALML6Calmodulin-like protein 6. (190 aa)
ADCY5Adenylate cyclase type 5 isoform X1. (1263 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC103085385Neuroendocrine secretory protein 55-like. (242 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
PPP3CCSerine/threonine-protein phosphatase. (583 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1976 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1868 aa)
PDE3APhosphodiesterase. (1138 aa)
PPP3CBSerine/threonine-protein phosphatase. (480 aa)
PPP3R2LOW QUALITY PROTEIN: calcineurin subunit B type 2. (170 aa)
KCNJ2Inward rectifier potassium channel 2. (427 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (658 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide isoform X1. (176 aa)
LOC103087287Angiotensin-converting enzyme. (1302 aa)
CLCA2Calcium-activated chloride channel regulator 2. (943 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta. (274 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
NPR1Guanylate cyclase. (1058 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
PDE1APhosphodiesterase. (441 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
LOC103075302Guanylate cyclase soluble subunit alpha-1-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
PDE3BPhosphodiesterase. (1121 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (551 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
CLCA4Calcium-activated chloride channel regulator 4-like. (933 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PPP3R1Calcineurin subunit B type 1. (160 aa)
LOC103089557Calcium-activated chloride channel regulator 1-like. (626 aa)
NPPANatriuretic peptides A. (152 aa)
ADCYAP1R1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (496 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
LOC103074541LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
CALML5Calmodulin-like protein 5. (140 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
PDE1CPhosphodiesterase. (769 aa)
GNAI2LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I) subunit alpha-2. (360 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
PDE1BPhosphodiesterase. (535 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2112 aa)
LOC103072349Calcium-activated potassium channel subunit alpha-1-like. (1073 aa)
ADRB1Beta-1 adrenergic receptor. (465 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (486 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (293 aa)
RENRenin isoform X1; Belongs to the peptidase A1 family. (407 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (335 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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