63 items (Lipotes vexillifer) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

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Your Input:
	AGTR1	Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	ADCY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
	ORAI1	Calcium release-activated calcium channel protein 1. (303 aa)
	LOC103068564	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
	ADCY1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
	SCARB1	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (509 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
	ADCY4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	MRAP	Melanocortin-2 receptor accessory protein. (186 aa)
	GNAS	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (991 aa)
	ADCY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (477 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
	KCNK2	Potassium channel subfamily K member 2-like isoform X2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (427 aa)
	ADCY5	Adenylate cyclase type 5 isoform X1. (1263 aa)
	LOC103085385	Neuroendocrine secretory protein 55-like. (242 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
	NR5A1	Steroidogenic factor 1 isoform X1. (461 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
	CACNA1F	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1976 aa)
	ATF4	Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1 isoform X1. (598 aa)
	ADCY9	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	ADCY3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1141 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
	CACNA1I	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2110 aa)
	CACNA1H	LOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1H. (2346 aa)
	CACNA1S	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1868 aa)
	CREB3	Cyclic AMP-responsive element-binding protein 3 isoform X1. (376 aa)
	POMC	Pro-opiomelanocortin. (261 aa)
	CREB3L1	Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
	NR0B1	Nuclear receptor subfamily 0 group B member 1. (464 aa)
	LOC103083046	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like; Belongs to the 3-beta-HSD family. (373 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta. (274 aa)
	PBX1	pre-B-cell leukemia transcription factor 1 isoform X1. (430 aa)
	GNAQ	Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
	MC2R	Adrenocorticotropic hormone receptor isoform X1. (297 aa)
	CREB3L4	Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1. (426 aa)
	GNA11	Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
	ATF6B	Cyclic AMP-dependent transcription factor ATF-6 beta isoform X1. (709 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
	LOC103069558	Steroid 21-hydroxylase-like; Belongs to the cytochrome P450 family. (497 aa)
	ADCY7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
	CREB3L3	Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X2. (458 aa)
	LDLR	Low-density lipoprotein receptor. (857 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	CACNA1G	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2389 aa)
	CREB5	Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
	LOC103089121	Cytochrome P450 11B1, mitochondrial-like isoform X1; Belongs to the cytochrome P450 family. (503 aa)
	NCEH1	Neutral cholesterol ester hydrolase 1 isoform X1. (408 aa)
	CREB3L2	Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2112 aa)
	LOC103074013	Potassium voltage-gated channel subfamily A member 4-like; Belongs to the potassium channel family. (663 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1. (293 aa)
	PDE8A	Phosphodiesterase. (837 aa)
	KCNK3	Potassium channel subfamily K member. (402 aa)
	LOC103081477	Steroid 17-alpha-hydroxylase/17,20 lyase-like; Belongs to the cytochrome P450 family. (509 aa)
	PDE8B	Phosphodiesterase. (885 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	A0A340WHT5	A0A340WEH1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.546
ADCY1	ADCY3	A0A340WHT5	A0A340X1W5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.940
ADCY1	ADCY4	A0A340WHT5	A0A340WK40	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.540
ADCY1	ADCY5	A0A340WHT5	A0A340WQ40	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5 isoform X1.	0.524
ADCY1	ADCY6	A0A340WHT5	A0A340WTP8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.523
ADCY1	ADCY7	A0A340WHT5	A0A340XKH5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.638
ADCY1	ADCY8	A0A340WHT5	A0A340WM11	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.953
ADCY1	ADCY9	A0A340WHT5	A0A340X0V2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.633
ADCY1	ATF4	A0A340WHT5	A0A340WXH5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Cyclic AMP-dependent transcription factor ATF-4.	0.495
ADCY1	CACNA1G	A0A340WHT5	A0A340XUY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]	0.446
ADCY1	GNAS	A0A340WHT5	A0A340WLE5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like.	0.961
ADCY1	LOC103085385	A0A340WHT5	A0A340WRC9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Neuroendocrine secretory protein 55-like.	0.900
ADCY1	PDE8A	A0A340WHT5	A0A340YCD9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.686
ADCY1	PDE8B	A0A340WHT5	A0A340YGH4	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.686
ADCY1	PRKACA	A0A340WHT5	A0A340Y602	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.925
ADCY1	PRKACB	A0A340WHT5	A0A340XE43	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta.	0.928
ADCY2	ADCY1	A0A340WEH1	A0A340WHT5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.546
ADCY2	ADCY4	A0A340WEH1	A0A340WK40	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.520
ADCY2	ADCY5	A0A340WEH1	A0A340WQ40	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5 isoform X1.	0.992
ADCY2	ADCY6	A0A340WEH1	A0A340WTP8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.774