STRINGSTRING
KRAS KRAS ITPR2 ITPR2 TRPC1 TRPC1 CACNA1D CACNA1D TRPC4 TRPC4 MAP2K1 MAP2K1 SPP1 SPP1 PRKCB PRKCB MAPK1 MAPK1 KCNN2 KCNN2 GABBR1 GABBR1 PLCB4 PLCB4 PLCB1 PLCB1 PIK3R3 PIK3R3 CACNA1F CACNA1F PIK3CD PIK3CD MAPK3 MAPK3 PRKCA PRKCA ITPR1 ITPR1 CACNA1I CACNA1I CACNA1H CACNA1H CACNA1S CACNA1S ARRB1 ARRB1 PIK3R1 PIK3R1 AKT1 AKT1 KCNN4 KCNN4 AKT2 AKT2 ARRB2 ARRB2 HCN3 HCN3 GNAQ GNAQ KCNN3 KCNN3 GNA11 GNA11 KISS1R KISS1R KCNJ11 KCNJ11 KCNN1 KCNN1 PRKCG PRKCG GNRH1 GNRH1 ESR2 ESR2 PLCB2 PLCB2 MAP2K2 MAP2K2 KCNJ9 KCNJ9 PLCB3 PLCB3 PIK3R2 PIK3R2 AKT3 AKT3 HCN2 HCN2 ITPR3 ITPR3 RAF1 RAF1 GABBR2 GABBR2 NRAS NRAS KCNJ5 KCNJ5 CACNA1G CACNA1G LHB LHB GNRH2 GNRH2 PIK3CB PIK3CB PIK3CA PIK3CA GPER1 GPER1 KCNJ3 KCNJ3 HRAS HRAS TRPC5 TRPC5 CGA CGA CACNA1C CACNA1C KCNJ6 KCNJ6 HCN1 HCN1 KISS1 KISS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KRASGTPase KRas. (188 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
TRPC1Short transient receptor potential channel 1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
TRPC4Short transient receptor potential channel 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
SPP1Osteopontin isoform X1. (296 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
KCNN2Small conductance calcium-activated potassium channel protein 2 isoform X1. (842 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (963 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1976 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2110 aa)
CACNA1HLOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1H. (2346 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1868 aa)
ARRB1Beta-arrestin-1. (418 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
KCNN4Intermediate conductance calcium-activated potassium channel protein 4. (428 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
ARRB2Beta-arrestin-2 isoform X1. (421 aa)
HCN3Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3. (786 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
KCNN3Small conductance calcium-activated potassium channel protein 3 isoform X1. (738 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
KISS1RkiSS-1 receptor. (395 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11 isoform X1. (388 aa)
KCNN1Small conductance calcium-activated potassium channel protein 1 isoform X1. (546 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (95 aa)
ESR2Estrogen receptor beta. (533 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
KCNJ9LOW QUALITY PROTEIN: G protein-activated inward rectifier potassium channel 3. (469 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
HCN2LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2. (904 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (940 aa)
NRASGTPase NRas. (189 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4 isoform X1. (419 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2389 aa)
LHBLutropin subunit beta. (141 aa)
GNRH2Progonadoliberin-2. (123 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
HRASGTPase HRas isoform X1. (189 aa)
TRPC5Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2112 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (423 aa)
HCN1Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (876 aa)
KISS1Metastasis-suppressor KiSS-1. (136 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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