STRINGSTRING
ADIPOQ ADIPOQ MAPK8 MAPK8 PRKCD PRKCD SOCS4 SOCS4 GCK GCK CACNA1D CACNA1D PRKCZ PRKCZ CACNA1E CACNA1E MAPK1 MAPK1 IRS2 IRS2 PIK3R3 PIK3R3 HK2 HK2 PIK3CD PIK3CD MAPK3 MAPK3 HK1 HK1 IKBKB IKBKB HKDC1 HKDC1 PIK3R1 PIK3R1 PKLR PKLR CACNA1B CACNA1B ABCC8 ABCC8 SLC2A4 SLC2A4 INSR INSR TNF TNF KCNJ11 KCNJ11 PRKCE PRKCE PIK3R2 PIK3R2 SOCS3 SOCS3 IRS4 IRS4 MTOR MTOR SLC2A2 SLC2A2 SOCS1 SOCS1 CACNA1G CACNA1G HK3 HK3 MAPK9 MAPK9 MAPK10 MAPK10 PIK3CB PIK3CB MAFA MAFA PIK3CA PIK3CA INS INS PKM PKM IRS1 IRS1 CACNA1C CACNA1C SOCS2 SOCS2 CACNA1A CACNA1A PDX1 PDX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADIPOQC1Q and collagen domain containing adiponectin. (242 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
GCKPhosphotransferase. (466 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2314 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
IRS2Insulin receptor substrate 2. (1362 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
HK2Hexokinase-2 isoform X1. (1002 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
HK1Hexokinase-1. (917 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
HKDC1Putative hexokinase HKDC1. (917 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2261 aa)
ABCC8ATP-binding cassette sub-family C member 8 isoform X1. (1582 aa)
SLC2A4Solute carrier family 2, facilitated glucose transporter member 4 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (550 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11 isoform X1. (388 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. (493 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
IRS4Insulin receptor substrate 4 isoform X1. (1267 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2544 aa)
SLC2A2Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
SOCS1Suppressor of cytokine signaling 1. (216 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2389 aa)
HK3Hexokinase-3. (924 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
MAFATranscription factor MafA. (335 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
IRS1Insulin receptor substrate 1. (1252 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2112 aa)
SOCS2Suppressor of cytokine signaling 2 isoform X1. (198 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2295 aa)
PDX1Pancreas/duodenum homeobox protein 1. (286 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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