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MYLK2 MYLK2 CAMK2B CAMK2B ADCY2 ADCY2 ATP1B3 ATP1B3 ACTB ACTB CALML4 CALML4 ITPR2 ITPR2 KCNE2 KCNE2 ADCY1 ADCY1 ADCY4 ADCY4 GNAS GNAS SST SST ADCY8 ADCY8 CAMK2A CAMK2A CFTR CFTR PRKCB PRKCB KCNK2 KCNK2 CALML6 CALML6 ADCY5 ADCY5 GNAI3 GNAI3 LOC103085385 LOC103085385 PLCB4 PLCB4 MYLK4 MYLK4 MYLK MYLK ATP1A1 ATP1A1 PLCB1 PLCB1 MYLK3 MYLK3 ADCY6 ADCY6 KCNJ16 KCNJ16 CAMK2D CAMK2D ADCY9 ADCY9 PRKCA PRKCA ADCY3 ADCY3 ITPR1 ITPR1 SLC9A4 SLC9A4 SSTR2 SSTR2 KCNJ2 KCNJ2 ATP1B2 ATP1B2 SLC26A7 SLC26A7 PRKACB PRKACB CCKBR CCKBR GNAQ GNAQ ATP1A4 ATP1A4 ATP1B1 ATP1B1 CALM3 CALM3 ATP1A3 ATP1A3 PRKCG PRKCG SLC9A1 SLC9A1 KCNJ10 KCNJ10 PLCB2 PLCB2 CA2 CA2 ADCY7 ADCY7 ATP1A2 ATP1A2 PLCB3 PLCB3 ACTG1 ACTG1 ITPR3 ITPR3 EZR EZR KCNK10 KCNK10 GAST GAST KCNJ1 KCNJ1 ATP1B4 ATP1B4 ATP4B ATP4B GNAI1 GNAI1 HRH2 HRH2 LOC103074541 LOC103074541 KCNQ1 KCNQ1 CALML5 CALML5 GNAI2 GNAI2 CAMK2G CAMK2G PRKACA PRKACA LOC103069138 LOC103069138 KCNJ15 KCNJ15 SLC4A2 SLC4A2 ATP4A ATP4A CALM1 CALM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYLK2Myosin light chain kinase 2, skeletal/cardiac muscle. (597 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
ACTBActin, cytoplasmic 1. (375 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2. (123 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (991 aa)
SSTSomatostatin. (116 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
KCNK2Potassium channel subfamily K member 2-like isoform X2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (427 aa)
CALML6Calmodulin-like protein 6. (190 aa)
ADCY5Adenylate cyclase type 5 isoform X1. (1263 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
LOC103085385Neuroendocrine secretory protein 55-like. (242 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (377 aa)
MYLKMyosin light chain kinase, smooth muscle isoform X1. (1962 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (919 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
MYLK3Myosin light chain kinase 3. (800 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
KCNJ16Inward rectifier potassium channel 16. (419 aa)
CAMK2DLOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type II subunit delta. (536 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1141 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
SSTR2Somatostatin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
KCNJ2Inward rectifier potassium channel 2. (427 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (294 aa)
SLC26A7Anion exchange transporter. (657 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta. (274 aa)
CCKBRGastrin/cholecystokinin type B receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (454 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (994 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (983 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
KCNJ10ATP-sensitive inward rectifier potassium channel 10. (379 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
CA2Carbonic anhydrase 2 isoform X1; Belongs to the alpha-carbonic anhydrase family. (260 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
EZREzrin isoform X1. (586 aa)
KCNK10Potassium channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (537 aa)
GASTGastrin. (103 aa)
KCNJ1ATP-sensitive inward rectifier potassium channel 1 isoform X1. (384 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (348 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
HRH2Histamine H2 receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC103074541LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (580 aa)
CALML5Calmodulin-like protein 5. (140 aa)
GNAI2LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I) subunit alpha-2. (360 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (672 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC103069138Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
KCNJ15ATP-sensitive inward rectifier potassium channel 15 isoform X1. (407 aa)
SLC4A2Anion exchange protein. (1242 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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