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| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1. (562 aa) |
| | ACTB | Actin, cytoplasmic 1. (375 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) |
| | SLC25A31 | ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa) |
| | KPNA7 | Importin subunit alpha; Functions in nuclear protein import. (563 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | PML | Protein PML. (848 aa) |
| | LOC103069427 | Polyadenylate-binding protein 2-like. (303 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1 isoform X1. (753 aa) |
| | IFNAR2 | LOW QUALITY PROTEIN: interferon alpha/beta receptor 2. (528 aa) |
| | IL6 | LOW QUALITY PROTEIN: interleukin-6. (243 aa) |
| | TMPRSS11D | Transmembrane protease serine; Belongs to the peptidase S1 family. (417 aa) |
| | LOC103079638 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (173 aa) |
| | IRF9 | Interferon regulatory factor 9. (412 aa) |
| | KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) |
| | LOC103076248 | Tumor necrosis factor receptor superfamily member 10A-like. (129 aa) |
| | LOC103069156 | Cytochrome c 2-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 isoform X1. (269 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (263 aa) |
| | IL33 | LOW QUALITY PROTEIN: interleukin-33. (485 aa) |
| | RAE1 | mRNA export factor. (368 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | LOC103086796 | SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like isoform X1; Belongs to the MHC class II family. (255 aa) |
| | RNASEL | LOW QUALITY PROTEIN: 2-5A-dependent ribonuclease. (736 aa) |
| | TLR4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (841 aa) |
| | IFNGR1 | LOW QUALITY PROTEIN: interferon gamma receptor 1. (471 aa) |
| | PIK3R3 | LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa) |
| | MX1 | LOW QUALITY PROTEIN: interferon-induced GTP-binding protein Mx1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (518 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | PYCARD | Apoptosis-associated speck-like protein containing a CARD isoform X1. (195 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa) |
| | CREBBP | CREB-binding protein isoform X1. (2429 aa) |
| | EP300 | Histone acetyltransferase p300. (2420 aa) |
| | CPSF4L | Cleavage and polyadenylation specificity factor subunit 4. (180 aa) |
| | LOC103087452 | DLA class II histocompatibility antigen, DR-1 beta chain-like. (269 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (325 aa) |
| | TMPRSS2 | Transmembrane protease serine 2; Belongs to the peptidase S1 family. (537 aa) |
| | LOC103090661 | Interferon alpha-1-like. (189 aa) |
| | MAVS | Mitochondrial antiviral-signaling protein. (514 aa) |
| | MX2 | LOW QUALITY PROTEIN: interferon-induced GTP-binding protein Mx2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (695 aa) |
| | LOC103069739 | Interferon alpha-1-like. (189 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa) |
| | TLR7 | Toll-like receptor 7 isoform X1. (1067 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (257 aa) |
| | NLRX1 | NLR family member X1. (986 aa) |
| | LOC103068617 | Interferon alpha-1-like. (188 aa) |
| | TMPRSS4 | Transmembrane protease serine 4 isoform X1; Belongs to the peptidase S1 family. (391 aa) |
| | LOC103078847 | Nuclear RNA export factor 2-like. (439 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | KPNA5 | Importin subunit alpha; Functions in nuclear protein import. (536 aa) |
| | LOC103091202 | Interferon alpha-1-like. (188 aa) |
| | LOC103069181 | Interferon alpha-1-like. (189 aa) |
| | LOC103073219 | LOW QUALITY PROTEIN: interferon alpha-8-like. (248 aa) |
| | LOC103073772 | Interferon beta-2-like. (186 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (341 aa) |
| | NXT1 | NTF2-related export protein 1. (140 aa) |
| | CXCL10 | C-X-C motif chemokine. (103 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | ADAR | Double-stranded RNA-specific adenosine deaminase. (1172 aa) |
| | CCL2 | C-C motif chemokine. (99 aa) |
| | HNRNPUL1 | Heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1. (857 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (419 aa) |
| | KPNA2 | Importin subunit alpha; Functions in nuclear protein import. (565 aa) |
| | CASP9 | Caspase-9 isoform X1; Belongs to the peptidase C14A family. (452 aa) |
| | LOC103087567 | HLA class II histocompatibility antigen, DR alpha chain-like; Belongs to the MHC class II family. (253 aa) |
| | LOC103073034 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (814 aa) |
| | LOC103068724 | Nuclear RNA export factor 2-like. (235 aa) |
| | FDPS | Farnesyl pyrophosphate synthase isoform X1; Belongs to the FPP/GGPP synthase family. (425 aa) |
| | LOC103069667 | Nuclear RNA export factor 3-like. (513 aa) |
| | SLC25A6 | ADP/ATP translocase 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (358 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (536 aa) |
| | LOC103085172 | HLA class II histocompatibility antigen, DM beta chain-like. (282 aa) |
| | LOC103087297 | HLA class II histocompatibility antigen, DRB1-4 beta chain-like. (266 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | TNFRSF10A | Tumor necrosis factor receptor superfamily member 10A. (426 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | LOC103078860 | Caspase-1-like; Belongs to the peptidase C14A family. (404 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | RAB11B | Ras-related protein Rab-11B. (218 aa) |
| | RELA | Transcription factor p65 isoform X1. (560 aa) |
| | LOC103085441 | HLA class II histocompatibility antigen, DM alpha chain-like; Belongs to the MHC class II family. (261 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa) |
| | ACTG1 | Actin, cytoplasmic 2. (375 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (225 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | VDAC1 | Voltage-dependent anion-selective channel protein 1 isoform X1. (283 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (701 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | TYK2 | Tyrosine-protein kinase. (1186 aa) |
| | CIITA | MHC class II transactivator. (1109 aa) |
| | LOC103075576 | Tumor necrosis factor receptor superfamily member 10A-like. (266 aa) |
| | LOC103086000 | HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa) |
| | LOC103069848 | Putative Bcl-2 homologous antagonist/killer 2-like. (211 aa) |
| | LOC103083691 | HLA class II histocompatibility antigen, DO beta chain-like isoform X1. (259 aa) |
| | NXF1 | Nuclear RNA export factor 1 isoform X1. (623 aa) |
| | LOC103081962 | NACHT, LRR and PYD domains-containing protein 3-like. (1037 aa) |
| | IRF3 | Interferon regulatory factor 3 isoform X1. (420 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | NXT2 | NTF2-related export protein 2. (141 aa) |
| | XPO1 | Exportin-1. (1071 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (304 aa) |
| | NUP98 | Nuclear pore complex protein Nup98-Nup96. (1817 aa) |
| | SLC25A5 | ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | NFKBIB | NF-kappa-B inhibitor beta. (353 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (288 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (977 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | TRIM25 | E3 ubiquitin/ISG15 ligase TRIM25. (634 aa) |
| | LOC103069117 | LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-like. (721 aa) |
| | LOC103075495 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC103073993 | Apoptosis-associated speck-like protein containing a CARD-like. (258 aa) |
| | TLR3 | LOW QUALITY PROTEIN: toll-like receptor 3; Belongs to the Toll-like receptor family. (956 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | IFIH1 | Interferon-induced helicase C domain-containing protein 1. (1022 aa) |
| | LOC103082631 | Anionic trypsin-like; Belongs to the peptidase S1 family. (247 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | CALCOCO2 | Calcium-binding and coiled-coil domain-containing protein 2 isoform X1. (469 aa) |
| | LOC103082362 | Cationic trypsin-like; Belongs to the peptidase S1 family. (246 aa) |
| | IRF7 | Interferon regulatory factor 7. (486 aa) |
| | LOC103083173 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CASP3 | Caspase-3; Belongs to the peptidase C14A family. (275 aa) |
| | SLC25A4 | ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | IFNGR2 | LOW QUALITY PROTEIN: interferon gamma receptor 2. (349 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (445 aa) |
| | IL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | STAT2 | Signal transducer and activator of transcription. (895 aa) |
| | BID | BH3-interacting domain death agonist. (297 aa) |
| | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase. (539 aa) |
| | PABPN1L | Embryonic polyadenylate-binding protein 2. (277 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (342 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthase 1-like. (390 aa) |
| | DNAJB1 | dnaJ homolog subfamily B member 1. (340 aa) |
| | OAS2 | LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 2. (707 aa) |
| | KPNA6 | Importin subunit alpha; Functions in nuclear protein import. (543 aa) |
| | DNAJC3 | dnaJ homolog subfamily C member 3. (504 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain-containing protein 2. (362 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha. (747 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (752 aa) |
| | PABPN1 | LOW QUALITY PROTEIN: poly(A) binding protein, nuclear 1. (305 aa) |
| | DDX58 | LOW QUALITY PROTEIN: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58. (886 aa) |
