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FZD8 | LOW QUALITY PROTEIN: frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (672 aa) | ||||
RHOA | Transforming protein RhoA isoform X1. (221 aa) | ||||
SOS2 | Son of sevenless homolog 2-like. (1272 aa) | ||||
WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) | ||||
CAMK2B | Calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa) | ||||
KRAS | GTPase KRas. (188 aa) | ||||
SRC | Tyrosine-protein kinase. (548 aa) | ||||
IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) | ||||
WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
ACTB | Actin, cytoplasmic 1. (375 aa) | ||||
SOS1 | Son of sevenless homolog 1. (1333 aa) | ||||
PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) | ||||
MSN | Moesin. (577 aa) | ||||
FZD4 | Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa) | ||||
FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa) | ||||
CD44 | CD44 antigen isoform X1. (745 aa) | ||||
PXN | Paxillin-like isoform X1; Belongs to the paxillin family. (591 aa) | ||||
LOC103089492 | Cathepsin L1-like; Belongs to the peptidase C1 family. (333 aa) | ||||
TIMP3 | Metalloproteinase inhibitor 3. (211 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (654 aa) | ||||
ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (800 aa) | ||||
TIAM1 | T-lymphoma invasion and metastasis-inducing protein 1 isoform X1. (1592 aa) | ||||
WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) | ||||
HPSE | Heparanase isoform X1. (542 aa) | ||||
VAV3 | Guanine nucleotide exchange factor VAV3 isoform X1. (875 aa) | ||||
EIF4B | Eukaryotic translation initiation factor 4B. (618 aa) | ||||
MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) | ||||
CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa) | ||||
CTSL | Cathepsin L1; Belongs to the peptidase C1 family. (332 aa) | ||||
PTCH1 | Protein patched homolog 1 isoform X1. (1448 aa) | ||||
RAC1 | Ras-related C3 botulinum toxin substrate 1 isoform X1. (201 aa) | ||||
MET | Hepatocyte growth factor receptor isoform X1. (1412 aa) | ||||
CAV2 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) | ||||
PPP1R12A | Protein phosphatase 1 regulatory subunit. (943 aa) | ||||
MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (263 aa) | ||||
LOC103082455 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) | ||||
HCLS1 | Hematopoietic lineage cell-specific protein isoform X1. (479 aa) | ||||
LOC103069249 | Collagen alpha-2(I) chain-like isoform X3. (1370 aa) | ||||
DROSHA | Ribonuclease 3 isoform X1. (1373 aa) | ||||
RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) | ||||
DCN | Decorin; May affect the rate of fibrils formation. (360 aa) | ||||
LUM | Lumican. (340 aa) | ||||
TLR4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (841 aa) | ||||
MMP9 | Matrix metalloproteinase-9. (708 aa) | ||||
PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) | ||||
KDR | Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) | ||||
ARAF | Serine/threonine-protein kinase A-Raf isoform X2. (609 aa) | ||||
PIK3R3 | LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa) | ||||
WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) | ||||
RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa) | ||||
HOXD10 | Homeobox protein Hox-D10. (410 aa) | ||||
ARHGEF12 | LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 12. (1563 aa) | ||||
VAV2 | Guanine nucleotide exchange factor VAV2 isoform X1. (878 aa) | ||||
ELK1 | ETS domain-containing protein Elk-1 isoform X1. (444 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa) | ||||
WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) | ||||
CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) | ||||
FZD1 | Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (644 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (350 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa) | ||||
IGF1 | Insulin-like growth factor I isoform X1. (174 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (325 aa) | ||||
VTN | Vitronectin isoform X1. (565 aa) | ||||
SDC2 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) | ||||
CAMK2D | LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type II subunit delta. (536 aa) | ||||
NUDT16L1 | Protein syndesmos. (211 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa) | ||||
ANK1 | Ankyrin-1 isoform X1. (1856 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa) | ||||
PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa) | ||||
TFAP4 | Transcription factor AP-4. (338 aa) | ||||
WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) | ||||
CBL | E3 ubiquitin-protein ligase CBL. (910 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
ANK2 | Ankyrin-2. (4188 aa) | ||||
PPP1R12B | Protein phosphatase 1 regulatory subunit. (890 aa) | ||||
HPSE2 | Inactive heparanase-2. (411 aa) | ||||
LOC103076632 | Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) | ||||
WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) | ||||
GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) | ||||
TWIST1 | Twist-related protein 1 isoform X1. (204 aa) | ||||
PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa) | ||||
ITGA2 | Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (440 aa) | ||||
ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
PLAUR | Urokinase plasminogen activator surface receptor. (334 aa) | ||||
ARHGEF1 | Rho guanine nucleotide exchange factor 1 isoform X1. (913 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) | ||||
LOC103086084 | LOW QUALITY PROTEIN: serine/threonine-protein phosphatase PP1-gamma catalytic subunit B-like. (375 aa) | ||||
ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) | ||||
FN1 | LOW QUALITY PROTEIN: fibronectin. (2483 aa) | ||||
WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1389 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) | ||||
DDX5 | Probable ATP-dependent RNA helicase DDX5 isoform X1; Belongs to the DEAD box helicase family. (614 aa) | ||||
PRKACB | cAMP-dependent protein kinase catalytic subunit beta. (274 aa) | ||||
FLNA | filamin-A isoform X1. (2647 aa) | ||||
WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa) | ||||
VEGFA | Vascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa) | ||||
WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) | ||||
HSPG2 | Basement membrane-specific heparan sulfate proteoglycan core protein. (4406 aa) | ||||
WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) | ||||
MMP2 | 72 kDa type IV collagenase. (584 aa) | ||||
ANK3 | Ankyrin-3-like isoform X1. (4377 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) | ||||
SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa) | ||||
CDC42 | Cell division control protein 42 homolog isoform X1. (191 aa) | ||||
HBEGF | Proheparin-binding EGF-like growth factor. (208 aa) | ||||
THBS1 | Thrombospondin-1. (1170 aa) | ||||
WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) | ||||
MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa) | ||||
ACTG1 | Actin, cytoplasmic 2. (375 aa) | ||||
RRAS2 | Ras-related protein R-Ras2 isoform X1. (127 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
VAV1 | Proto-oncogene vav isoform X1. (844 aa) | ||||
PAK1 | Non-specific serine/threonine protein kinase. (563 aa) | ||||
ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) | ||||
WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) | ||||
MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) | ||||
RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) | ||||
FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1209 aa) | ||||
GPC3 | Glypican-3 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa) | ||||
EZR | Ezrin isoform X1. (586 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2544 aa) | ||||
NRAS | GTPase NRas. (189 aa) | ||||
RRAS | Ras-related protein R-Ras. (218 aa) | ||||
HSPB2 | Heat shock protein beta-2; Belongs to the small heat shock protein (HSP20) family. (181 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) | ||||
SDC4 | Syndecan-4. (201 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) | ||||
FZD6 | Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) | ||||
FRS2 | Fibroblast growth factor receptor substrate 2. (508 aa) | ||||
CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) | ||||
SDC1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa) | ||||
GAB1 | GRB2-associated-binding protein 1 isoform X1. (723 aa) | ||||
LOC103071971 | Collagen alpha-1(I) chain-like. (1463 aa) | ||||
FZD3 | Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) | ||||
MRAS | Ras-related protein M-Ras isoform X1. (208 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) | ||||
CTNNB1 | Catenin beta-1 isoform X1. (781 aa) | ||||
LOC103090179 | Toll-like receptor 2-like isoform X1; Belongs to the Toll-like receptor family. (785 aa) | ||||
PTK2 | Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1003 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) | ||||
WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (366 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog. (467 aa) | ||||
CTTN | Src substrate cortactin isoform X1. (538 aa) | ||||
CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) | ||||
HRAS | GTPase HRas isoform X1. (189 aa) | ||||
IGF2 | Insulin-like growth factor II isoform X1. (237 aa) | ||||
CASP3 | Caspase-3; Belongs to the peptidase C14A family. (275 aa) | ||||
BRAF | Serine/threonine-protein kinase B-raf. (763 aa) | ||||
PLAU | Urokinase-type plasminogen activator isoform X1. (440 aa) | ||||
CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma. (672 aa) | ||||
HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa) | ||||
PRKACA | cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa) | ||||
ERBB3 | Receptor tyrosine-protein kinase erbB-3. (1338 aa) | ||||
CD63 | Tetraspanin. (236 aa) | ||||
ITGA5 | Integrin alpha-5; Belongs to the integrin alpha chain family. (1053 aa) | ||||
FZD7 | Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) | ||||
FZD9 | Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (545 aa) | ||||
CDKN1A | Cyclin-dependent kinase inhibitor 1 isoform X1. (164 aa) | ||||
PDCD4 | Programmed cell death protein 4 isoform X1. (469 aa) | ||||
PPP1R12C | Protein phosphatase 1 regulatory subunit. (784 aa) | ||||
GPC1 | Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (560 aa) | ||||
ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1367 aa) | ||||
FAS | Tumor necrosis factor receptor superfamily member 6. (342 aa) | ||||
WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa) | ||||
FLNB | filamin-B isoform X1. (2633 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) | ||||
WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (837 aa) | ||||
TWIST2 | Twist-related protein 2. (160 aa) | ||||
IQGAP1 | Ras GTPase-activating-like protein IQGAP1. (1627 aa) | ||||
RPS6 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa) | ||||
PLCE1 | Phosphoinositide phospholipase C. (2303 aa) | ||||
NANOG | Homeobox protein NANOG. (306 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) | ||||
FLNC | filamin-C isoform X1. (2720 aa) | ||||
SMO | Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa) | ||||
FZD10 | LOW QUALITY PROTEIN: frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (563 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
RDX | Radixin isoform X1. (583 aa) | ||||
HIF1A | Hypoxia-inducible factor 1-alpha isoform X2. (822 aa) | ||||
PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa) | ||||
ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (805 aa) | ||||
ITGAV | Integrin alpha-V; Belongs to the integrin alpha chain family. (1311 aa) |