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LOC103075485 | Progesterone receptor-like isoform X1. (936 aa) | ||||
FZD8 | LOW QUALITY PROTEIN: frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (672 aa) | ||||
SOS2 | Son of sevenless homolog 2-like. (1272 aa) | ||||
SHC3 | SHC-transforming protein 3. (588 aa) | ||||
WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) | ||||
NCOA3 | Nuclear receptor coactivator. (1462 aa) | ||||
KRAS | GTPase KRas. (188 aa) | ||||
FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
CSNK1A1 | Casein kinase I isoform alpha isoform X1; Belongs to the protein kinase superfamily. (365 aa) | ||||
E2F1 | Transcription factor E2F1. (437 aa) | ||||
WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa) | ||||
GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) | ||||
SOS1 | Son of sevenless homolog 1. (1333 aa) | ||||
FZD4 | Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) | ||||
HEY2 | Hairy/enhancer-of-split related with YRPW motif protein 2. (352 aa) | ||||
HES5 | Transcription factor HES-5. (173 aa) | ||||
DVL1 | Segment polarity protein dishevelled homolog DVL-1 isoform X2. (699 aa) | ||||
WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) | ||||
LRP5 | Low-density lipoprotein receptor-related protein 5. (1451 aa) | ||||
GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) | ||||
MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) | ||||
MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (263 aa) | ||||
RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) | ||||
DLL3 | LOW QUALITY PROTEIN: delta-like protein 3. (609 aa) | ||||
JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (727 aa) | ||||
HEY1 | Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1. (308 aa) | ||||
ARAF | Serine/threonine-protein kinase A-Raf isoform X2. (609 aa) | ||||
PIK3R3 | LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa) | ||||
WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) | ||||
RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa) | ||||
APC | Adenomatous polyposis coli protein isoform X1. (2847 aa) | ||||
FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa) | ||||
WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) | ||||
FZD1 | Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (644 aa) | ||||
IGF1 | Insulin-like growth factor I isoform X1. (174 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (325 aa) | ||||
LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (399 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) | ||||
NCOA1 | Nuclear receptor coactivator. (1440 aa) | ||||
FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) | ||||
SHC4 | SHC-transforming protein 4 isoform X1. (631 aa) | ||||
AXIN1 | Axin-1. (866 aa) | ||||
DDB2 | DNA damage-binding protein 2 isoform X1. (463 aa) | ||||
HEYL | Hairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (323 aa) | ||||
WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) | ||||
JAG2 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1234 aa) | ||||
FRAT1 | Proto-oncogene FRAT1. (277 aa) | ||||
LOC103076632 | Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) | ||||
WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) | ||||
GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) | ||||
PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) | ||||
E2F3 | Transcription factor E2F3. (469 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
NOTCH2 | Neurogenic locus notch homolog protein 2-like. (2471 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (440 aa) | ||||
AXIN2 | Axin-2. (846 aa) | ||||
LOC103072956 | Uncharacterized protein LOC103072956. (225 aa) | ||||
SHC1 | SHC-transforming protein 1 isoform X1. (584 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa) | ||||
FRAT2 | GSK-3-binding protein FRAT2. (230 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) | ||||
ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) | ||||
WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
HES1 | Transcription factor HES-1. (280 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) | ||||
DVL2 | Segment polarity protein dishevelled homolog DVL-2. (734 aa) | ||||
WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa) | ||||
APC2 | Adenomatous polyposis coli protein 2. (2237 aa) | ||||
FGF22 | LOW QUALITY PROTEIN: fibroblast growth factor 22; Belongs to the heparin-binding growth factors family. (229 aa) | ||||
E2F2 | Transcription factor E2F2. (439 aa) | ||||
WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) | ||||
WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) | ||||
FOS | Proto-oncogene c-Fos isoform X1. (380 aa) | ||||
NOTCH3 | Neurogenic locus notch homolog protein 3. (2274 aa) | ||||
NOTCH1 | Neurogenic locus notch homolog protein 1. (2536 aa) | ||||
ESR2 | Estrogen receptor beta. (533 aa) | ||||
POLK | DNA polymerase kappa. (885 aa) | ||||
NOTCH4 | Neurogenic locus notch homolog protein 4. (1993 aa) | ||||
WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) | ||||
SHC2 | SHC-transforming protein 2. (801 aa) | ||||
MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) | ||||
FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) | ||||
DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) | ||||
PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa) | ||||
GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) | ||||
GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa) | ||||
JUN | Transcription factor AP-1; Belongs to the bZIP family. (337 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
LOC103069848 | Putative Bcl-2 homologous antagonist/killer 2-like. (211 aa) | ||||
BAX | Apoptosis regulator BAX isoform X1. (192 aa) | ||||
TCF7 | Transcription factor 7. (252 aa) | ||||
WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) | ||||
RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) | ||||
FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1209 aa) | ||||
BRCA2 | LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein. (3441 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2544 aa) | ||||
NRAS | GTPase NRas. (189 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa) | ||||
FZD6 | Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) | ||||
FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
LOC103081170 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (465 aa) | ||||
FZD3 | Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) | ||||
CTNNB1 | Catenin beta-1 isoform X1. (781 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa) | ||||
FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) | ||||
WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) | ||||
FLT4 | Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1594 aa) | ||||
WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) | ||||
FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) | ||||
HRAS | GTPase HRas isoform X1. (189 aa) | ||||
RB1 | Retinoblastoma-associated protein isoform X1. (929 aa) | ||||
BRAF | Serine/threonine-protein kinase B-raf. (763 aa) | ||||
LOC103073470 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1156 aa) | ||||
FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa) | ||||
FZD7 | Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) | ||||
FZD9 | Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (545 aa) | ||||
CDKN1A | Cyclin-dependent kinase inhibitor 1 isoform X1. (164 aa) | ||||
FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (244 aa) | ||||
TCF7L2 | Transcription factor 7-like 2. (584 aa) | ||||
CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1367 aa) | ||||
PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) | ||||
NFKB2 | Nuclear factor NF-kappa-B p100 subunit isoform X1. (899 aa) | ||||
TNFSF11 | Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa) | ||||
WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa) | ||||
DVL3 | Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa) | ||||
WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (837 aa) | ||||
LRP6 | Low-density lipoprotein receptor-related protein 6 isoform X1. (1463 aa) | ||||
FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) | ||||
FZD10 | LOW QUALITY PROTEIN: frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (563 aa) | ||||
TCF7L1 | Transcription factor 7-like 1. (713 aa) | ||||
FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (232 aa) | ||||
FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (266 aa) |