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| | FZD8 | LOW QUALITY PROTEIN: frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (672 aa) |
| | SOS2 | Son of sevenless homolog 2-like. (1272 aa) |
| | SHC3 | SHC-transforming protein 3. (588 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | KRAS | GTPase KRas. (188 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | CSNK1A1 | Casein kinase I isoform alpha isoform X1; Belongs to the protein kinase superfamily. (365 aa) |
| | E2F1 | Transcription factor E2F1. (437 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | SOS1 | Son of sevenless homolog 1. (1333 aa) |
| | LOC103080445 | Catenin alpha-2-like isoform X1. (585 aa) |
| | ABCB1 | Multidrug resistance protein 1. (1284 aa) |
| | FZD4 | Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | DVL1 | Segment polarity protein dishevelled homolog DVL-1 isoform X2. (699 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein 5. (1451 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa) |
| | CDH1 | Cadherin-1 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa) |
| | MET | Hepatocyte growth factor receptor isoform X1. (1412 aa) |
| | MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (263 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf isoform X2. (609 aa) |
| | PIK3R3 | LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa) |
| | APC | Adenomatous polyposis coli protein isoform X1. (2847 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | CDH17 | Cadherin-17. (820 aa) |
| | FZD1 | Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (644 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (325 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (399 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | RXRA | Retinoic acid receptor RXR-alpha isoform X1. (439 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | SHC4 | SHC-transforming protein 4 isoform X1. (631 aa) |
| | AXIN1 | Axin-1. (866 aa) |
| | DDB2 | DNA damage-binding protein 2 isoform X1. (463 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | FRAT1 | Proto-oncogene FRAT1. (277 aa) |
| | LOC103076632 | Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | E2F3 | Transcription factor E2F3. (469 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa) |
| | CDKN2B | Cyclin-dependent kinase 4 inhibitor B. (131 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (440 aa) |
| | AXIN2 | Axin-2. (846 aa) |
| | SHC1 | SHC-transforming protein 1 isoform X1. (584 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (591 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | FRAT2 | GSK-3-binding protein FRAT2. (230 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) |
| | CTNNA3 | Catenin alpha-3. (702 aa) |
| | RXRG | Retinoic acid receptor RXR-gamma. (463 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) |
| | TGFB3 | Transforming growth factor beta-3. (456 aa) |
| | DVL2 | Segment polarity protein dishevelled homolog DVL-2. (734 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa) |
| | APC2 | Adenomatous polyposis coli protein 2. (2237 aa) |
| | FGF22 | LOW QUALITY PROTEIN: fibroblast growth factor 22; Belongs to the heparin-binding growth factors family. (229 aa) |
| | E2F2 | Transcription factor E2F2. (439 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | CTNNA1 | Catenin alpha-1 isoform X1. (906 aa) |
| | POLK | DNA polymerase kappa. (885 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | SHC2 | SHC-transforming protein 2. (801 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MLH1 | DNA mismatch repair protein Mlh1 isoform X1. (757 aa) |
| | LOC103069848 | Putative Bcl-2 homologous antagonist/killer 2-like. (211 aa) |
| | RXRB | Retinoic acid receptor RXR-beta isoform X1. (538 aa) |
| | BAX | Apoptosis regulator BAX isoform X1. (192 aa) |
| | TCF7 | Transcription factor 7. (252 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2544 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (232 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa) |
| | FZD6 | Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | RARB | Retinoic acid receptor beta isoform X1. (458 aa) |
| | CTNNA2 | Catenin alpha-2-like. (452 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (553 aa) |
| | GAB1 | GRB2-associated-binding protein 1 isoform X1. (723 aa) |
| | LOC103081170 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (465 aa) |
| | FZD3 | Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | CTNNB1 | Catenin beta-1 isoform X1. (781 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | MUC2 | Mucin-2. (3417 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | RB1 | Retinoblastoma-associated protein isoform X1. (929 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf. (763 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa) |
| | FZD7 | Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | FZD9 | Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (545 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1 isoform X1. (164 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (244 aa) |
| | TCF7L2 | Transcription factor 7-like 2. (584 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa) |
| | DVL3 | Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (839 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein 6 isoform X1. (1463 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1127 aa) |
| | FZD10 | LOW QUALITY PROTEIN: frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (563 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | TCF7L1 | Transcription factor 7-like 1. (713 aa) |
| | CDX2 | Homeobox protein CDX-2. (303 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (232 aa) |
| | REG4 | LOW QUALITY PROTEIN: regenerating islet-derived family, member 4. (144 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (266 aa) |
