STRINGSTRING
MAPK8 MAPK8 SOS2 SOS2 KRAS KRAS SLC44A1 SLC44A1 SLC44A5 SLC44A5 DGKD DGKD SOS1 SOS1 EIF4EBP1 EIF4EBP1 GPCPD1 GPCPD1 MAP2K1 MAP2K1 PDGFRB PDGFRB RAC1 RAC1 PRKCB PRKCB WAS WAS MAPK1 MAPK1 CHKA CHKA RPS6KB1 RPS6KB1 LOC103069618 LOC103069618 PDGFD PDGFD WASF1 WASF1 PIK3R3 PIK3R3 RPS6KB2 RPS6KB2 DGKG DGKG DGKK DGKK PIK3CD PIK3CD PLA2G4A PLA2G4A MAPK3 MAPK3 RALGDS RALGDS PRKCA PRKCA TSC1 TSC1 PDPK1 PDPK1 PDGFRA PDGFRA TSC2 TSC2 CHKB CHKB RAC2 RAC2 PDGFB PDGFB GRB2 GRB2 PIK3R1 PIK3R1 AKT1 AKT1 SLC22A2 SLC22A2 SLC22A3 SLC22A3 LOC103072956 LOC103072956 PLD2 PLD2 DGKZ DGKZ AKT2 AKT2 SLC5A7 SLC5A7 SLC44A4 SLC44A4 SLC22A1 SLC22A1 PLA2G4F PLA2G4F PIP5K1A PIP5K1A PIP5K1C PIP5K1C FOS FOS PRKCG PRKCG WASF2 WASF2 SLC22A5 SLC22A5 SLC22A4 SLC22A4 PLA2G4B PLA2G4B MAP2K2 MAP2K2 PIK3R2 PIK3R2 PLA2G4D PLA2G4D PPAP2C PPAP2C JUN JUN PLA2G4E PLA2G4E AKT3 AKT3 SLC44A2 SLC44A2 RAF1 RAF1 EGFR EGFR LOC103071679 LOC103071679 PDGFC PDGFC MTOR MTOR NRAS NRAS RAC3 RAC3 PPAP2B PPAP2B PLCG1 PLCG1 DGKB DGKB EGF EGF MAPK9 MAPK9 MAPK10 MAPK10 PCYT1A PCYT1A DGKE DGKE PCYT1B PCYT1B PIK3CB PIK3CB PIP5K1B PIP5K1B PLD1 PLD1 PIK3CA PIK3CA PDGFA PDGFA CHPT1 CHPT1 DGKQ DGKQ SLC44A3 SLC44A3 HRAS HRAS DGKI DGKI DGKA DGKA DGKH DGKH RHEB RHEB WASF3 WASF3 HIF1A HIF1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK8Mitogen-activated protein kinase. (427 aa)
SOS2Son of sevenless homolog 2-like. (1272 aa)
KRASGTPase KRas. (188 aa)
SLC44A1Choline transporter-like protein 1; Belongs to the CTL (choline transporter-like) family. (737 aa)
SLC44A5Choline transporter-like protein 5; Belongs to the CTL (choline transporter-like) family. (752 aa)
DGKDDiacylglycerol kinase. (1222 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa)
GPCPD1Glycerophosphocholine phosphodiesterase GPCPD1-like. (672 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (201 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
CHKACholine kinase alpha isoform X1. (450 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
LOC103069618GTP-binding protein Rheb-like. (184 aa)
PDGFDPlatelet-derived growth factor D-like isoform X1. (370 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (559 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa)
DGKGDiacylglycerol kinase. (791 aa)
DGKKDiacylglycerol kinase. (1229 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
PLA2G4APhospholipase A2. (749 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
RALGDSRal guanine nucleotide dissociation stimulator. (842 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
TSC1Hamartin isoform X1. (1170 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
TSC2Tuberin. (1793 aa)
CHKBCholine/ethanolamine kinase. (395 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
SLC22A2Solute carrier family 22 member 2. (554 aa)
SLC22A3Solute carrier family 22 member 3. (545 aa)
LOC103072956Uncharacterized protein LOC103072956. (225 aa)
PLD2Phospholipase. (933 aa)
DGKZDiacylglycerol kinase. (1120 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
SLC5A7High affinity choline transporter 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (523 aa)
SLC44A4Choline transporter-like protein 4 isoform X1; Belongs to the CTL (choline transporter-like) family. (706 aa)
SLC22A1Solute carrier family 22 member 1. (568 aa)
PLA2G4FPhospholipase A2. (849 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (828 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
WASF2wiskott-Aldrich syndrome protein family member 2 isoform X1. (498 aa)
SLC22A5Solute carrier family 22 member 5. (557 aa)
SLC22A4Solute carrier family 22 member 4 isoform X1. (553 aa)
PLA2G4BPhospholipase A2. (780 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
PLA2G4DPhospholipase A2. (818 aa)
PPAP2CLOW QUALITY PROTEIN: lipid phosphate phosphohydrolase 2. (550 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (337 aa)
PLA2G4EPhospholipase A2. (883 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
SLC44A2Choline transporter-like protein 2; Belongs to the CTL (choline transporter-like) family. (706 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
LOC103071679Acyl-protein thioesterase 1-like isoform X1. (210 aa)
PDGFCPlatelet-derived growth factor C. (345 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2544 aa)
NRASGTPase NRas. (189 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (192 aa)
PPAP2BLipid phosphate phosphohydrolase 3. (312 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
DGKBDiacylglycerol kinase beta. (597 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PCYT1ACholine-phosphate cytidylyltransferase A. (367 aa)
DGKEDiacylglycerol kinase. (602 aa)
PCYT1BCholine-phosphate cytidylyltransferase B. (425 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1. (540 aa)
PLD1Phospholipase. (1074 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
CHPT1Cholinephosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (346 aa)
DGKQDiacylglycerol kinase. (937 aa)
SLC44A3Choline transporter-like protein 3 isoform X1; Belongs to the CTL (choline transporter-like) family. (651 aa)
HRASGTPase HRas isoform X1. (189 aa)
DGKIDiacylglycerol kinase. (1078 aa)
DGKADiacylglycerol kinase. (734 aa)
DGKHDiacylglycerol kinase. (1216 aa)
RHEBGTP-binding protein Rheb. (184 aa)
WASF3wiskott-Aldrich syndrome protein family member 3. (502 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X2. (822 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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