STRINGSTRING
DES DES ITGA11 ITGA11 DAG1 DAG1 ACTB ACTB SLC8A1 SLC8A1 PRKAG3 PRKAG3 EDN1 EDN1 PRKAB2 PRKAB2 CACNB2 CACNB2 ATP2A2 ATP2A2 CACNG2 CACNG2 ITGB5 ITGB5 CACNA1D CACNA1D CACNA2D3 CACNA2D3 IL6 IL6 CACNG3 CACNG3 AGT AGT ITGB7 ITGB7 MYH7 MYH7 MYH6 MYH6 CACNB3 CACNB3 PRKAG1 PRKAG1 TNNC1 TNNC1 LAMA2 LAMA2 LOC103074022 LOC103074022 CACNA1F CACNA1F SGCD SGCD RYR2 RYR2 IGF1 IGF1 CACNA2D2 CACNA2D2 ATP2A3 ATP2A3 ATP2A1 ATP2A1 ITGB6 ITGB6 ITGA2B ITGA2B CACNG1 CACNG1 SGCB SGCB CACNA1S CACNA1S TNNT2 TNNT2 ITGB4 ITGB4 DMD DMD ITGB8 ITGB8 ITGA1 ITGA1 EMD EMD ITGA2 ITGA2 CACNG5 CACNG5 LMNA LMNA TPM3 TPM3 MYBPC3 MYBPC3 ITGB3 ITGB3 TPM2 TPM2 SLC8A2 SLC8A2 TPM1 TPM1 CACNG7 CACNG7 CACNG6 CACNG6 LOC103087287 LOC103087287 TGFB3 TGFB3 ITGA6 ITGA6 CACNG8 CACNG8 LAMA1 LAMA1 ITGA10 ITGA10 LOC103080144 LOC103080144 TNF TNF TPM4 TPM4 TGFB1 TGFB1 ACTG1 ACTG1 ITGA9 ITGA9 ITGA8 ITGA8 ITGA4 ITGA4 CACNB4 CACNB4 ACTC1 ACTC1 PRKAA2 PRKAA2 PRKAB1 PRKAB1 SGCA SGCA ITGA3 ITGA3 CACNB1 CACNB1 MYL2 MYL2 ITGA7 ITGA7 ITGA5 ITGA5 CACNA2D1 CACNA2D1 TNNI3 TNNI3 CACNA1C CACNA1C CACNA2D4 CACNA2D4 PRKAG2 PRKAG2 PRKAA1 PRKAA1 MYL3 MYL3 TGFB2 TGFB2 SGCG SGCG ITGB1 ITGB1 ITGAV ITGAV
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DESDesmin; Belongs to the intermediate filament family. (470 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1188 aa)
DAG1Dystroglycan isoform X1. (895 aa)
ACTBActin, cytoplasmic 1. (375 aa)
SLC8A1Sodium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (970 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3 isoform X3. (482 aa)
EDN1Endothelin-1. (202 aa)
PRKAB25'-AMP-activated protein kinase subunit beta-2. (272 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (651 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1039 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
CACNA2D3Voltage-dependent calcium channel subunit alpha-2/delta-3. (810 aa)
IL6LOW QUALITY PROTEIN: interleukin-6. (243 aa)
CACNG3Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (780 aa)
MYH7Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
MYH6Myosin-6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
CACNB3Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (484 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X2. (336 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
LAMA2Laminin subunit alpha-2 isoform X1. (3125 aa)
LOC103074022Titin-like. (32000 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1976 aa)
SGCDDelta-sarcoglycan-like. (289 aa)
RYR2Ryanodine receptor 2-like. (4986 aa)
IGF1Insulin-like growth factor I isoform X1. (174 aa)
CACNA2D2Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1. (1153 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1000 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (808 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (1035 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
SGCBBeta-sarcoglycan. (465 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1868 aa)
TNNT2Troponin T, cardiac muscle. (280 aa)
ITGB4Integrin beta. (1754 aa)
DMDDystrophin. (3585 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
ITGA1Integrin alpha-1 isoform X1; Belongs to the integrin alpha chain family. (1179 aa)
EMDEmerin. (259 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
LMNAprelamin-A/C isoform X1; Belongs to the intermediate filament family. (664 aa)
TPM3Tropomyosin alpha-3 chain isoform X1; Belongs to the tropomyosin family. (284 aa)
MYBPC3Myosin-binding protein C, cardiac-type. (1272 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
TPM2Tropomyosin beta chain isoform X1; Belongs to the tropomyosin family. (323 aa)
SLC8A2Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
TPM1Tropomyosin alpha-4 chain isoform X1; Belongs to the tropomyosin family. (326 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit. (225 aa)
LOC103087287Angiotensin-converting enzyme. (1302 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
ITGA6Integrin alpha-6; Belongs to the integrin alpha chain family. (1091 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (448 aa)
LAMA1Laminin subunit alpha-1. (3063 aa)
ITGA10Integrin alpha-10 isoform X1; Belongs to the integrin alpha chain family. (1167 aa)
LOC103080144Sodium/calcium exchanger 3-like; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (595 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
TPM4Tropomyosin alpha-4 chain isoform X1; Belongs to the tropomyosin family. (284 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
ITGA9Integrin alpha-9; Belongs to the integrin alpha chain family. (1035 aa)
ITGA8Integrin alpha-8; Belongs to the integrin alpha chain family. (1060 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (519 aa)
ACTC1Actin, alpha cardiac muscle 1 isoform X1. (386 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (270 aa)
SGCAAlpha-sarcoglycan. (455 aa)
ITGA3Integrin alpha-3 isoform X1; Belongs to the integrin alpha chain family. (1068 aa)
CACNB1LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit beta-1. (678 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
ITGA7Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1141 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1053 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1. (959 aa)
TNNI3Troponin I, cardiac muscle. (211 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2112 aa)
CACNA2D4Voltage-dependent calcium channel subunit alpha-2/delta-4. (1153 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (569 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
MYL3Myosin light chain 3. (197 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SGCGGamma-sarcoglycan. (291 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (805 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (1311 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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