STRINGSTRING
DES DES ITGA11 ITGA11 DAG1 DAG1 ACTB ACTB LOC103080445 LOC103080445 SLC8A1 SLC8A1 CACNB2 CACNB2 ATP2A2 ATP2A2 CACNG2 CACNG2 ITGB5 ITGB5 CACNA1D CACNA1D CACNA2D3 CACNA2D3 CACNG3 CACNG3 ITGB7 ITGB7 CACNB3 CACNB3 LAMA2 LAMA2 CACNA1F CACNA1F SGCD SGCD RYR2 RYR2 CACNA2D2 CACNA2D2 ATP2A3 ATP2A3 ATP2A1 ATP2A1 PKP2 PKP2 ACTN2 ACTN2 LEF1 LEF1 ITGB6 ITGB6 ITGA2B ITGA2B DSC2 DSC2 CACNG1 CACNG1 CDH2 CDH2 SGCB SGCB CACNA1S CACNA1S ITGB4 ITGB4 DMD DMD ITGB8 ITGB8 ITGA1 ITGA1 EMD EMD ITGA2 ITGA2 DSG2 DSG2 CACNG5 CACNG5 LMNA LMNA ITGB3 ITGB3 SLC8A2 SLC8A2 CTNNA3 CTNNA3 CACNG7 CACNG7 CACNG6 CACNG6 ITGA6 ITGA6 CACNG8 CACNG8 LAMA1 LAMA1 ITGA10 ITGA10 LOC103080144 LOC103080144 CTNNA1 CTNNA1 ACTG1 ACTG1 ITGA9 ITGA9 ITGA8 ITGA8 TCF7 TCF7 ITGA4 ITGA4 CACNB4 CACNB4 ACTN3 ACTN3 SGCA SGCA CTNNA2 CTNNA2 ITGA3 ITGA3 CTNNB1 CTNNB1 DSP DSP CACNB1 CACNB1 ITGA7 ITGA7 ITGA5 ITGA5 CACNA2D1 CACNA2D1 CACNA1C CACNA1C CACNA2D4 CACNA2D4 TCF7L2 TCF7L2 TCF7L1 TCF7L1 GJA1 GJA1 SGCG SGCG ITGB1 ITGB1 ITGAV ITGAV
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DESDesmin; Belongs to the intermediate filament family. (470 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1188 aa)
DAG1Dystroglycan isoform X1. (895 aa)
ACTBActin, cytoplasmic 1. (375 aa)
LOC103080445Catenin alpha-2-like isoform X1. (585 aa)
SLC8A1Sodium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (970 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (651 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1039 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
CACNA2D3Voltage-dependent calcium channel subunit alpha-2/delta-3. (810 aa)
CACNG3Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (780 aa)
CACNB3Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (484 aa)
LAMA2Laminin subunit alpha-2 isoform X1. (3125 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1976 aa)
SGCDDelta-sarcoglycan-like. (289 aa)
RYR2Ryanodine receptor 2-like. (4986 aa)
CACNA2D2Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1. (1153 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1000 aa)
PKP2Plakophilin-2. (826 aa)
ACTN2Alpha-actinin-2 isoform X1. (907 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (808 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (1035 aa)
DSC2Desmocollin-2 isoform X1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (906 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
SGCBBeta-sarcoglycan. (465 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1868 aa)
ITGB4Integrin beta. (1754 aa)
DMDDystrophin. (3585 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
ITGA1Integrin alpha-1 isoform X1; Belongs to the integrin alpha chain family. (1179 aa)
EMDEmerin. (259 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
DSG2Desmoglein-2. (1191 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
LMNAprelamin-A/C isoform X1; Belongs to the intermediate filament family. (664 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
SLC8A2Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
CTNNA3Catenin alpha-3. (702 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit. (225 aa)
ITGA6Integrin alpha-6; Belongs to the integrin alpha chain family. (1091 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (448 aa)
LAMA1Laminin subunit alpha-1. (3063 aa)
ITGA10Integrin alpha-10 isoform X1; Belongs to the integrin alpha chain family. (1167 aa)
LOC103080144Sodium/calcium exchanger 3-like; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (595 aa)
CTNNA1Catenin alpha-1 isoform X1. (906 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
ITGA9Integrin alpha-9; Belongs to the integrin alpha chain family. (1035 aa)
ITGA8Integrin alpha-8; Belongs to the integrin alpha chain family. (1060 aa)
TCF7Transcription factor 7. (252 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (519 aa)
ACTN3Alpha-actinin-3 isoform X1. (902 aa)
SGCAAlpha-sarcoglycan. (455 aa)
CTNNA2Catenin alpha-2-like. (452 aa)
ITGA3Integrin alpha-3 isoform X1; Belongs to the integrin alpha chain family. (1068 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
DSPDesmoplakin isoform X1. (2877 aa)
CACNB1LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit beta-1. (678 aa)
ITGA7Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1141 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1053 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1. (959 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2112 aa)
CACNA2D4Voltage-dependent calcium channel subunit alpha-2/delta-4. (1153 aa)
TCF7L2Transcription factor 7-like 2. (584 aa)
TCF7L1Transcription factor 7-like 1. (713 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (383 aa)
SGCGGamma-sarcoglycan. (291 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (805 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (1311 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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