STRINGSTRING
cbiO-1 cbiO-1 cobL-1 cobL-1 cobN-1 cobN-1 cobA-hemD cobA-hemD hemA hemA bchD bchD cobD cobD APB32477.1 APB32477.1 APB32536.1 APB32536.1 APB32542.1 APB32542.1 natC natC APB32581.1 APB32581.1 APB32704.1 APB32704.1 hemE hemE cbiD cbiD cobA cobA APB32747.1 APB32747.1 cbiO-2 cbiO-2 APB32768.1 APB32768.1 APB32795.1 APB32795.1 APB32796.1 APB32796.1 APB32797.1 APB32797.1 APB32798.1 APB32798.1 APB32799.1 APB32799.1 APB32800.1 APB32800.1 APB32801.1 APB32801.1 APB32802.1 APB32802.1 APB32803.1 APB32803.1 APB32851.1 APB32851.1 por por sir sir cysH cysH cysU-1 cysU-1 sbp-1 sbp-1 hemF hemF ubiD ubiD fbpC fbpC fbpB fbpB cysA cysA APB33121.1 APB33121.1 hemH hemH APB33193.1 APB33193.1 APB33194.1 APB33194.1 APB33201.1 APB33201.1 ubiX ubiX APB33203.1 APB33203.1 APB33204.1 APB33204.1 natE natE chlE chlE nodI nodI APB33303.1 APB33303.1 APB33304.1 APB33304.1 livK livK cbiP cbiP cysW-1 cysW-1 APB33402.1 APB33402.1 APB33403.1 APB33403.1 hemL hemL APB33450.1 APB33450.1 APB33477.1 APB33477.1 APB33478.1 APB33478.1 APB33479.1 APB33479.1 APB33480.1 APB33480.1 APB33496.1 APB33496.1 hemC hemC bchI bchI APB33577.1 APB33577.1 APB33579.1 APB33579.1 APB33590.1 APB33590.1 APB33591.1 APB33591.1 APB33592.1 APB33592.1 APB33593.1 APB33593.1 APB33594.1 APB33594.1 APB33595.1 APB33595.1 APB33643.1 APB33643.1 btuR-1 btuR-1 APB33651.1 APB33651.1 hemZ-1 hemZ-1 APB33670.1 APB33670.1 APB33711.1 APB33711.1 APB33718.1 APB33718.1 cbiF cbiF APB33846.1 APB33846.1 natA natA pucC pucC APB33895.1 APB33895.1 nodJ nodJ APB33981.1 APB33981.1 APB33986.1 APB33986.1 APB34008.1 APB34008.1 APB34009.1 APB34009.1 frhB frhB APB34056.1 APB34056.1 APB34067.1 APB34067.1 APB34073.1 APB34073.1 APB34074.1 APB34074.1 narB narB nirA nirA nasF nasF nasE nasE cynD cynD nasD nasD moeA moeA moaA moaA moaC moaC moaD-1 moaD-1 moaE moaE APB34129.1 APB34129.1 APB34136.1 APB34136.1 fbpA fbpA APB34187.1 APB34187.1 bchH bchH APB34194.1 APB34194.1 cobV cobV bchG bchG sbp-2 sbp-2 cysU-2 cysU-2 cysW-2 cysW-2 met3 met3 bchM bchM APB34286.1 APB34286.1 APB34306.1 APB34306.1 APB34307.1 APB34307.1 APB34308.1 APB34308.1 APB34335.1 APB34335.1 cbiC cbiC czcB czcB APB34382.1 APB34382.1 APB34393.1 APB34393.1 APB34402.1 APB34402.1 moaD-2 moaD-2 cobB-cbiA cobB-cbiA APB34450.1 APB34450.1 gpmB gpmB APB34529.1 APB34529.1 cbiQ cbiQ APB34534.1 APB34534.1 btuR-2 btuR-2 cobI-cbiL cobI-cbiL APB34617.1 APB34617.1 APB34722.1 APB34722.1 APB34766.1 APB34766.1 APB34767.1 APB34767.1 APB34788.1 APB34788.1 natB natB arsH arsH natD natD APB34843.1 APB34843.1 APB34846.1 APB34846.1 bchP bchP APB34850.1 APB34850.1 cbiX cbiX APB34852.1 APB34852.1 potA potA potD potD potC potC APB34960.1 APB34960.1 APB35013.1 APB35013.1 APB35022.1 APB35022.1 chlL chlL APB35030.1 APB35030.1 chlN chlN APB35078.1 APB35078.1 bioY bioY lspA lspA APB35088.1 APB35088.1 btuR-3 btuR-3 cobU cobU APB35162.1 APB35162.1 cbiJ cbiJ chlB chlB APB35196.1 APB35196.1 APB35197.1 APB35197.1 cobL-2 cobL-2 cobN-2 cobN-2 APB35293.1 APB35293.1 potB potB ubiA ubiA cbiGH-cobJ cbiGH-cobJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cbiO-1Polyamine-transporting ATPase. (231 aa)
cobL-1precorrin-6B methylase. (196 aa)
cobN-1Hydrogenobyrinic acid a,c-diamide cobaltochelatase. (491 aa)
cobA-hemDuroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (497 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (430 aa)
bchDMagnesium chelatase ATPase subunit D; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (659 aa)
cobDCobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (333 aa)
APB32477.1Putative sugar transport inner protein. (257 aa)
APB32536.1Peptidoglycan-binding domain 1 protein. (272 aa)
APB32542.1Permease of oligopeptide ABC transporter. (359 aa)
natCInner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (352 aa)
APB32581.1ABC-type multidrug transport system, permease component. (186 aa)
APB32704.1ABC transporter-like protein; Belongs to the ABC transporter superfamily. (340 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (350 aa)
cbiDCobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (367 aa)
cobAuroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (238 aa)
APB32747.1ABC transporter ATP-binding protein. (296 aa)
cbiO-2ABC transporter-like protein. (210 aa)
APB32768.1Hypothetical protein. (151 aa)
APB32795.1Alkaline phosphatase-like protein. (205 aa)
APB32796.1Transcriptional regulator, PadR-like family protein. (178 aa)
APB32797.1Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (448 aa)
APB32798.1Hydrophobe/amphiphile efflux-1 (HAE1) family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1065 aa)
APB32799.1Phage integrase; Belongs to the 'phage' integrase family. (398 aa)
APB32800.1Hypothetical protein. (232 aa)
APB32801.1Hypothetical protein. (135 aa)
APB32802.1Hypothetical protein. (199 aa)
APB32803.1Hypothetical protein. (1029 aa)
APB32851.1Putative redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family. (72 aa)
porProtochlorophyllide oxidoreductase; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide). (320 aa)
sirSulfite reductase subunit beta; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (593 aa)
cysHPhosphoadenosine phosphosulfate reductase; Belongs to the PAPS reductase family. CysH subfamily. (263 aa)
cysU-1Sulfate transport system permease; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (272 aa)
sbp-1Sulfate transport system substrate-binding protein thiosulfate-binding protein. (342 aa)
hemFCoproporphyrinogen oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. (338 aa)
ubiDUbiD family decarboxylase; Belongs to the UbiD family. (505 aa)
fbpCABC transporter-like protein ABC transporter; Belongs to the ABC transporter superfamily. (352 aa)
fbpBBinding-protein-dependent transporters inner membrane component. (533 aa)
cysASulfate ABC transporter ATPase; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (338 aa)
APB33121.1Glyoxalase/bleomycin resistance protein/dioxygenase. (126 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (388 aa)
APB33193.1Secretion protein HlyD. (361 aa)
APB33194.1DevC protein. (412 aa)
APB33201.1Hypothetical protein. (103 aa)
ubiXAromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (202 aa)
APB33203.1Hypothetical protein. (139 aa)
APB33204.1Hypothetical protein. (362 aa)
natEHigh-affinity branched-chain amino acid transport ATP-binding protein; BraG. (246 aa)
chlEMagnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (358 aa)
nodIABC transporter, ATP-binding protein. (302 aa)
APB33303.1RND multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1088 aa)
APB33304.1RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (410 aa)
livKAmino acid ABC transporter amino acid-binding protein. (416 aa)
cbiPCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (486 aa)
cysW-1ABC-type sulfate transport system, permease component. (277 aa)
APB33402.1ABC-type antimicrobial peptide transport system, permease component. (418 aa)
APB33403.1Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (430 aa)
hemLGlutamate-1-semialdehyde aminotransferase. (434 aa)
APB33450.1ABC-2 transporter, permease. (255 aa)
APB33477.1TetR family transcriptional regulator. (199 aa)
APB33478.1Membrane-fusion protein. (388 aa)
APB33479.1DevC protein. (408 aa)
APB33480.1ABC exporter ATP-binding subunit, DevA family. (235 aa)
APB33496.1Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (363 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (317 aa)
bchIMagnesium-chelatase subunit; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (363 aa)
APB33577.1ABC-type multidrug transport system, permease component. (258 aa)
APB33579.1RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (429 aa)
APB33590.1Protein of unknown function DUF1311. (150 aa)
APB33591.1ABC-type uncharacterized transport system involved in gliding motility, auxiliary component. (499 aa)
APB33592.1ABC transporter. (266 aa)
APB33593.1ATP-binding protein of ABC transporter. (325 aa)
APB33594.1Hypothetical protein. (82 aa)
APB33595.1Hypothetical protein. (110 aa)
APB33643.1ABC transporter; Belongs to the ABC transporter superfamily. (567 aa)
btuR-1cob(I)yrinic acid a,c-diamide adenosyltransferase. (176 aa)
APB33651.1FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits. (806 aa)
hemZ-1Radical SAM domain-containing protein. (483 aa)
APB33670.1ABC transporter. (257 aa)
APB33711.1Periplasmic polyamine-binding protein. (351 aa)
APB33718.1Von Willebrand factor type A. (565 aa)
cbiFPrecorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (246 aa)
APB33846.1Nitroreductase. (219 aa)
natAABC transporter. (256 aa)
pucCPUCC protein. (462 aa)
APB33895.1ATPase; Belongs to the ABC transporter superfamily. (531 aa)
nodJABC-2 type transporter superfamily. (264 aa)
APB33981.1OppC in a binding protein-dependent transport system. (367 aa)
APB33986.1Extracellular solute-binding protein. (359 aa)
APB34008.1ABC transporter permease protein. (405 aa)
APB34009.1ABC transporter. (238 aa)
frhBCoenzyme F420-reducing hydrogenase, beta subunit. (395 aa)
APB34056.1Extracellular solute-binding protein. (211 aa)
APB34067.1Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (399 aa)
APB34073.1LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (305 aa)
APB34074.1Hypothetical protein. (142 aa)
narBNitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (704 aa)
nirANitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (529 aa)
nasFNitrate/nitrite transport system substrate-binding protein. (434 aa)
nasENitrate ABC transporter inner membrane protein. (269 aa)
cynDABC-type nitrate transport atp-binding protein. (281 aa)
nasDABC-type nitrate transport atp-binding protein. (626 aa)
moeAMolybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (387 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (312 aa)
moaCBifunctional molybdopterin-guanine dinucleotide biosynthesis protein MoaC/MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (345 aa)
moaD-1Molybdopterin converting factor, subunit 1. (85 aa)
moaEMolybdopterin converting factor, subunit 2. (143 aa)
APB34129.1Sulfate-transporting ATPase. (311 aa)
APB34136.1Binding-protein-dependent transport systems inner membrane component. (284 aa)
fbpAExtracellular solute-binding protein family 1. (351 aa)
APB34187.1BadM/Rrf2 family transcriptional regulator. (141 aa)
bchHMagnesium chelatase. (1323 aa)
APB34194.1Outer membrane protein. (533 aa)
cobVCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (249 aa)
bchGBacteriochlorophyll/chlorophyll a synthase. (318 aa)
sbp-2Thiosulfate-binding protein. (188 aa)
cysU-2Sulfate ABC transporter inner membrane subunit CysT sulfate ABC transporter inner membrane protein. (141 aa)
cysW-2ABC-type sulfate transport system, permease component. (106 aa)
met3Sulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (384 aa)
bchMMg-protoporphyrin IX methyl transferase. (237 aa)
APB34286.1Extracellular solute-binding protein family 1. (415 aa)
APB34306.1Aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein. (356 aa)
APB34307.1Binding-protein-dependent transport systems inner membrane component. (282 aa)
APB34308.1Putative nitrate transport ATP-binding protein nrtD. (264 aa)
APB34335.1Efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (425 aa)
cbiCprecorrin-8X methylmutase. (212 aa)
czcBRND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (550 aa)
APB34382.1Cation efflux system protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1052 aa)
APB34393.1ABC transporter related. (314 aa)
APB34402.1ABC exporter ATP-binding subunit, DevA family. (244 aa)
moaD-2Molybdopterin converting factor, small subunit. (91 aa)
cobB-cbiACobyrinic acid a,c-diamide synthase. (433 aa)
APB34450.1Hypothetical protein. (552 aa)
gpmBPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (432 aa)
APB34529.1Hypothetical protein. (242 aa)
cbiQCobalt transport protein. (289 aa)
APB34534.1Daunorubicin resistance ABC transporter ATPase subunit. (326 aa)
btuR-2ATP:corrinoid adenosyltransferase. (377 aa)
cobI-cbiLPrecorrin-2 methyltransferase; Belongs to the precorrin methyltransferase family. (234 aa)
APB34617.1ABC-type dipeptide transport system, periplasmic component. (537 aa)
APB34722.1Aromatic amino acid beta-eliminating lyase/threonine aldolase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (385 aa)
APB34766.1Protein of unknown function DUF433. (82 aa)
APB34767.1Hypothetical protein. (90 aa)
APB34788.1ABC transporter ATP-binding protein. (928 aa)
natBPeriplasmic binding protein. (407 aa)
arsHNADPH-dependent FMN reductase. (215 aa)
natDInner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (288 aa)
APB34843.1CHP701-containing protein. (184 aa)
APB34846.1L-threonine-O-3-phosphate decarboxylase. (350 aa)
bchPGeranylgeranyl reductase. (406 aa)
APB34850.1Binding-protein-dependent transport systems inner membrane component. (324 aa)
cbiXSirohydrochlorin ferrochelatase. (321 aa)
APB34852.1Geranylgeranyl reductase family protein. (375 aa)
potASpermidine/putrescine ABC transporter ATPase; Belongs to the ABC transporter superfamily. (375 aa)
potDExtracellular solute-binding protein family 1. (362 aa)
potCBinding-protein-dependent transport systems inner membrane component. (266 aa)
APB34960.1Class V aminotransferase. (384 aa)
APB35013.1Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (327 aa)
APB35022.1Binding-protein-dependent transport systems inner membrane component. (278 aa)
chlLProtochlorophyllide reductase iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (284 aa)
APB35030.1Hypothetical protein. (117 aa)
chlNLight-independent protochlorophyllide reductase subunit N; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (454 aa)
APB35078.1Hypothetical protein. (163 aa)
bioYBioY family. (191 aa)
lspALipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (154 aa)
APB35088.1Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (440 aa)
btuR-3cob(I)yrinic acid a,c-diamide adenosyltransferase. (199 aa)
cobUCobalbumin biosynthesis protein. (193 aa)
APB35162.1Amidohydrolase. (397 aa)
cbiJCobalt-precorrin-6x reductase. (249 aa)
chlBLight-independent protochlorophyllide reductase subunit B; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (508 aa)
APB35196.1RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (420 aa)
APB35197.1Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1028 aa)
cobL-2precorrin-6Y C5,15-methyltransferase. (409 aa)
cobN-2Cobaltochelatase, CobN subunit. (729 aa)
APB35293.1Hypothetical protein. (373 aa)
potBBinding-protein-dependent transport systems inner membrane component. (285 aa)
ubiA4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of plastoquinone-9 (PQ-9) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 4-hydroxy-3-solanesylbenzoate. Belongs to the UbiA prenyltransferase family. (329 aa)
cbiGH-cobJprecorrin-3B C17-methyltransferase. (616 aa)
Your Current Organism:
Gloeomargarita lithophora
NCBI taxonomy Id: 1188229
Other names: Candidatus Gloeomargarita lithophora D10, G. lithophora Alchichica-D10, Gloeomargarita lithophora Alchichica-D10, Gloeomargarita lithophora PMC 919.15
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