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glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa) | ||||
purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (206 aa) | ||||
rlmI | PUA domain-containing protein. (396 aa) | ||||
tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (368 aa) | ||||
metH | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1182 aa) | ||||
folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa) | ||||
APB33126.1 | Hypothetical protein. (209 aa) | ||||
APB33154.1 | HNH endonuclease. (198 aa) | ||||
APB33182.1 | Hypothetical protein. (494 aa) | ||||
purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (277 aa) | ||||
APB33460.1 | RDD family protein. (260 aa) | ||||
purH | Bifunctional purine biosynthesis protein purH / phosphoribosylaminoimidazolecarboxamide formyltransferase. (512 aa) | ||||
APB33695.1 | Hypothetical protein. (313 aa) | ||||
fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (332 aa) | ||||
APB34304.1 | Urea carboxylase-associated protein 1. (211 aa) | ||||
APB34305.1 | Urea carboxylase-associated protein 2. (262 aa) | ||||
APB34639.1 | Restriction endonuclease. (165 aa) | ||||
metF | Putative methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (328 aa) | ||||
APB34989.1 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (170 aa) | ||||
APB35139.1 | Glycine cleavage system aminomethyltransferase T. (352 aa) |