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SDL80678.1 SDL80678.1 SDL80738.1 SDL80738.1 trpA-2 trpA-2 trpB-2 trpB-2 trpF trpF aroC aroC SDL88660.1 SDL88660.1 SDM08566.1 SDM08566.1 hisC hisC SDM17461.1 SDM17461.1 trpC trpC trpD trpD SDM19694.1 SDM19694.1 trpE trpE SDM20705.1 SDM20705.1 aroE aroE SDL26996.1 SDL26996.1 trpB trpB trpA trpA aroA aroA SDK85927.1 SDK85927.1 aroB aroB aroK aroK SDL60011.1 SDL60011.1 SDL70900.1 SDL70900.1 SDL71725.1 SDL71725.1 aroQ aroQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SDL80678.1Phenylalanine 4-hydroxylase. (270 aa)
SDL80738.1Aromatic-amino-acid transaminase. (396 aa)
trpA-2Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
trpB-2Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (404 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (206 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa)
SDL88660.1Histidinol-phosphate aminotransferase. (366 aa)
SDM08566.1Cyclohexadienyl dehydratase; Belongs to the bacterial solute-binding protein 3 family. (262 aa)
hisCHistidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (351 aa)
SDM17461.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (364 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (268 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (341 aa)
SDM19694.1Anthranilate synthase, component II. (196 aa)
trpEAnthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (499 aa)
SDM20705.13-dehydroquinate synthase. (433 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (270 aa)
SDL26996.1Hypothetical protein. (444 aa)
trpBTryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (401 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (271 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (753 aa)
SDK85927.1Chorismate mutase. (363 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (371 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (180 aa)
SDL60011.1Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (195 aa)
SDL70900.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (359 aa)
SDL71725.1MAF protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (202 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa)
Your Current Organism:
Halomonas muralis
NCBI taxonomy Id: 119000
Other names: DSM 14789, H. muralis, Halomonas muralis Heyrman et al. 2002, Halomonas sp. LMG-19418, LMG 20969, LMG:20969
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