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| | SDM18376.1 | Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (917 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (341 aa) |
| | SDM19694.1 | Anthranilate synthase, component II. (196 aa) |
| | trpE | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (499 aa) |
| | SDM19849.1 | Putative endonuclease. (100 aa) |
| | SDM19880.1 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (232 aa) |
| | SDM20705.1 | 3-dehydroquinate synthase. (433 aa) |
| | ilvD-2 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (614 aa) |
| | SDM25865.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (363 aa) |
| | argD | acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (404 aa) |
| | SDK76589.1 | Acetylornithine deacetylase. (385 aa) |
| | SDK79236.1 | Citrate synthase; Belongs to the citrate synthase family. (429 aa) |
| | SDK81979.1 | Isocitrate dehydrogenase (NADP). (418 aa) |
| | SDK82763.1 | Alanine-synthesizing transaminase. (410 aa) |
| | argJ | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (404 aa) |
| | serC | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa) |
| | SDK85927.1 | Chorismate mutase. (363 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (753 aa) |
| | SDK86161.1 | UPF0716 protein FxsA. (171 aa) |
| | SDK86719.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (305 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa) |
| | SDK89636.1 | Aconitase; Belongs to the aconitase/IPM isomerase family. (872 aa) |
| | mtnN | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (241 aa) |
| | luxS | S-ribosylhomocysteine lyase /quorum-sensing autoinducer 2 (AI-2) synthesis protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (156 aa) |
| | SDK97335.1 | Cysteine synthase A. (352 aa) |
| | SDK97371.1 | Cystathionine gamma-lyase. (387 aa) |
| | SDL00146.1 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1243 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (147 aa) |
| | SDL00613.1 | Diaminobutyrate aminotransferase apoenzyme; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa) |
| | SDL01518.1 | Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (221 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (271 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (401 aa) |
| | SDL17668.1 | Transcriptional regulator, RpiR family. (287 aa) |
| | SDL19089.1 | Threonine dehydratase. (333 aa) |
| | SDL19806.1 | Cysteine synthase A. (382 aa) |
| | SDL21815.1 | Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (442 aa) |
| | hisD | Sulfopropanediol 3-dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (438 aa) |
| | SDL24496.1 | Predicted arabinose efflux permease, MFS family. (553 aa) |
| | metE | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (767 aa) |
| | SDL25598.1 | Lipocalin-like domain-containing protein. (150 aa) |
| | SDL26996.1 | Hypothetical protein. (444 aa) |
| | SDL27805.1 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (459 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (267 aa) |
| | SDL29560.1 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (352 aa) |
| | ilvE | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa) |
| | SDL35656.1 | Serine O-acetyltransferase. (306 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (270 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa) |
| | SDL37925.1 | Predicted arabinose efflux permease, MFS family. (408 aa) |
| | argA | N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. (437 aa) |
| | SDL39490.1 | Aspartate kinase; Belongs to the aspartokinase family. (416 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (431 aa) |
| | SDL40384.1 | Glutamate synthase (NADPH) small subunit. (472 aa) |
| | SDL40406.1 | Glutamate synthase (NADPH) large subunit. (1484 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (371 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (180 aa) |
| | dapA | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (406 aa) |
| | SDL48555.1 | Transketolase; Belongs to the transketolase family. (667 aa) |
| | SDL48597.1 | Fructose-bisphosphate aldolase. (350 aa) |
| | SDL48849.1 | L-glutamine synthetase. (468 aa) |
| | SDL50316.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (532 aa) |
| | SDL50958.1 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. (307 aa) |
| | SDL51109.1 | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (580 aa) |
| | SDL52550.1 | Transcriptional regulator, RpiR family. (284 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (373 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (223 aa) |
| | ilvA | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa) |
| | gpmI | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (524 aa) |
| | SDL55976.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (280 aa) |
| | hisD-2 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (440 aa) |
| | hisG | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (218 aa) |
| | SDL60011.1 | Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (195 aa) |
| | SDL60347.1 | Glutamine synthetase. (459 aa) |
| | SDL60615.1 | Glutamine synthetase. (454 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (309 aa) |
| | SDL62144.1 | 4-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. (294 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (485 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (275 aa) |
| | metXS | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (385 aa) |
| | SDL84900.1 | Aspartate/methionine/tyrosine aminotransferase. (386 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | argH | Argininosuccinate lyase. (471 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (277 aa) |
| | SDL88660.1 | Histidinol-phosphate aminotransferase. (366 aa) |
| | SDL89519.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (416 aa) |
| | SDL89644.1 | Transcriptional regulator, RpiR family. (287 aa) |
| | SDL89950.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (238 aa) |
| | glyA-2 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa) |
| | SDL94159.1 | L-threonine ammonia-lyase. (317 aa) |
| | SDL95771.1 | Glutamine synthetase. (459 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (563 aa) |
| | SDM00737.1 | Phosphoserine phosphatase. (403 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (396 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (565 aa) |
| | argB | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (301 aa) |
| | SDM07194.1 | L-threonine synthase. (462 aa) |
| | SDM07222.1 | Homoserine dehydrogenase. (438 aa) |
| | SDM07784.1 | Cystathione beta-lyase. (384 aa) |
| | SDM08566.1 | Cyclohexadienyl dehydratase; Belongs to the bacterial solute-binding protein 3 family. (262 aa) |
| | thrB | Homoserine kinase; Belongs to the pseudomonas-type ThrB family. (317 aa) |
| | SDM09020.1 | (S)-sulfolactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (309 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (202 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (215 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (251 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisC | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (351 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | SDM11350.1 | Acetolactate synthase, small subunit. (163 aa) |
| | SDM11367.1 | Acetolactate synthase, large subunit. (574 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (380 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (387 aa) |
| | SDM15720.1 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | SDM15976.1 | Ribose-5-phosphate isomerase. (161 aa) |
| | tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (319 aa) |
| | SDM16086.1 | Transketolase; Belongs to the transketolase family. (663 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase. (112 aa) |
| | SDM17461.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (364 aa) |
| | SDM18138.1 | Succinyldiaminopimelate aminotransferase apoenzyme. (404 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (341 aa) |
| | dapE | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (387 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (268 aa) |
| | SDL62641.1 | Acetolactate synthase, large subunit; Belongs to the TPP enzyme family. (562 aa) |
| | SDL62764.1 | Transposase. (341 aa) |
| | SDL63838.1 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (481 aa) |
| | SDL64394.1 | Aconitase. (648 aa) |
| | SDL64543.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (299 aa) |
| | SDL67952.1 | Hypothetical protein. (87 aa) |
| | SDL68398.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (538 aa) |
| | SDL70286.1 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (298 aa) |
| | SDL70900.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (359 aa) |
| | SDL71725.1 | MAF protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (202 aa) |
| | SDL71845.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (550 aa) |
| | SDL75732.1 | Pyruvate kinase, alpha/beta domain; Belongs to the pyruvate kinase family. (222 aa) |
| | SDL75847.1 | Pyruvate carboxylase subunit B. (602 aa) |
| | SDL75873.1 | Pyruvate carboxylase subunit A. (471 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (441 aa) |
| | pfp | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (419 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa) |
| | srkA | Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (327 aa) |
| | SDL79546.1 | Diaminopimelate decarboxylase. (430 aa) |
| | SDL80678.1 | Phenylalanine 4-hydroxylase. (270 aa) |
| | SDL80738.1 | Aromatic-amino-acid transaminase. (396 aa) |
| | trpA-2 | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa) |
| | trpB-2 | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (404 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (206 aa) |
| | asd | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (370 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (360 aa) |
| | leuD | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (219 aa) |
