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JBW_00073 JBW_00073 ilvD ilvD JBW_00549 JBW_00549 ilvC ilvC leuA leuA leuB leuB JBW_00553 JBW_00553 ilvE ilvE JBW_01095 JBW_01095 JBW_01161 JBW_01161 JBW_01162 JBW_01162 argJ argJ argJ-2 argJ-2 JBW_01781 JBW_01781 JBW_01782 JBW_01782 JBW_01789 JBW_01789 JBW_02324 JBW_02324 asd asd leuA-2 leuA-2 JBW_03477 JBW_03477 leuC leuC leuD leuD leuC-2 leuC-2 leuD-2 leuD-2 JBW_03827 JBW_03827 argD argD argB argB argJ-3 argJ-3 argC argC JBW_03994 JBW_03994 JBW_04219 JBW_04219 JBW_04222 JBW_04222 JBW_04259 JBW_04259 JBW_04283 JBW_04283 JBW_04520 JBW_04520
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
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JBW_00073PFAM: GCN5-related N-acetyltransferase; KEGG: N-acetyltransferase GCN5. (143 aa)
ilvDTIGRFAM: dihydroxy-acid dehydratase; KEGG: Dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; HAMAP : Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (550 aa)
JBW_00549PFAM: Acetolactate synthase, small subunit; KEGG: acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit. (181 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (333 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (508 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (358 aa)
JBW_00553Acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein, thiamine pyrophosphate central domain-containing protein; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; KEGG: acetolactate synthase, large subunit, biosynthetic type. (557 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (304 aa)
JBW_01095Aminodeoxychorismate lyase; PFAM: aminotransferase class IV; KEGG: ilvE, branched-chain amino acid aminotransferase. (292 aa)
JBW_01161KEGG: acetolactate synthase large subunit; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein, thiamine pyrophosphate central domain-containing protein. (566 aa)
JBW_01162TIGRFAM: acetolactate synthase, small subunit; KEGG: acetolactate synthase small subunit; PFAM: Acetolactate synthase, small subunit. (165 aa)
argJArginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (401 aa)
argJ-2Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (403 aa)
JBW_017813-isopropylmalate dehydratase; KEGG: aconitase A; PFAM: aconitate hydratase domain-containing protein. (779 aa)
JBW_01782KEGG: isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isopropylmalate dehydrogenase-like domain; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa)
JBW_01789Acetolactate synthase; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein, thiamine pyrophosphate central domain-containing protein; KEGG: acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. (587 aa)
JBW_02324Aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; KEGG: aspartate kinase; TIGRFAM: aspartate kinase, monofunctional class, aspartate kinase; Belongs to the aspartokinase family. (406 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa)
leuA-22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (520 aa)
JBW_03477TIGRFAM: aspartate kinase, monofunctional class, aspartate kinase; KEGG: putative aspartokinase; PFAM: aspartate/glutamate/uridylate kinase, amino acid-binding ACT domain-containing protein; Belongs to the aspartokinase family. (411 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (417 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (164 aa)
leuC-23-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (418 aa)
leuD-23-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (160 aa)
JBW_03827KEGG: branched chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV. (357 aa)
argDKEGG: argD, putative acetylornithine aminotransferase; HAMAP : Acetylornithine/succinyldiaminopimelate aminotransferase; PFAM: aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (396 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (294 aa)
argJ-3Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (401 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (343 aa)
JBW_03994KEGG: putative acetyltransferase; PFAM: GCN5-related N-acetyltransferase; Belongs to the acetyltransferase family. (150 aa)
JBW_04219Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: amino acid aminotransferase. (395 aa)
JBW_04222Transcriptional regulator, GntR family with aminotransferase domain containing protein; KEGG: regulatory protein GntR; PFAM: aminotransferase class I and II, regulatory protein GntR HTH; SMART: regulatory protein GntR HTH. (503 aa)
JBW_04259KEGG: dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (545 aa)
JBW_042833-isopropylmalate dehydratase; KEGG: hypothetical protein; PFAM: aconitate hydratase domain-containing protein. (781 aa)
JBW_04520PFAM: aconitate hydratase domain-containing protein; TIGRFAM: aconitate hydratase; KEGG: aconitate hydratase. (640 aa)
Your Current Organism:
Pelosinus fermentans
NCBI taxonomy Id: 1192197
Other names: P. fermentans JBW45, Pelosinus fermentans JBW45, Pelosinus fermentans str. JBW45, Pelosinus fermentans strain JBW45
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