STRINGSTRING
phhB phhB hrpB hrpB EKJ85930.1 EKJ85930.1 EKJ87632.1 EKJ87632.1 clpS_1 clpS_1 mtnC mtnC clpS_2 clpS_2 ribF ribF EKJ86824.1 EKJ86824.1 thyX thyX EKJ86593.1 EKJ86593.1 queD queD EKJ86319.1 EKJ86319.1 EKJ86598.1 EKJ86598.1 ispE ispE miaA miaA EKJ88238.1 EKJ88238.1 EKJ88408.1 EKJ88408.1 ubiX ubiX EKJ85644.1 EKJ85644.1 EKJ84867.1 EKJ84867.1 mtnD mtnD pdhA pdhA nadD nadD clpS_3 clpS_3 EKJ85366.1 EKJ85366.1 EKJ88558.1 EKJ88558.1 EKJ88785.1 EKJ88785.1 EKJ88756.1 EKJ88756.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
phhB4a-hydroxytetrahydrobiopterin dehydratase. (98 aa)
hrpBATP-dependent helicase HrpB. (821 aa)
EKJ85930.1ADP-ribosylglycohydrolase. (314 aa)
EKJ87632.1Putative deoxyribodipyrimidine photo-lyase. (472 aa)
clpS_1ATP-dependent Clp protease adaptor protein ClpS; Belongs to the ClpS family. (94 aa)
mtnC2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (243 aa)
clpS_2ATP-dependent Clp protease adaptor protein ClpS; Belongs to the ClpS family. (108 aa)
ribFRiboflavin biosynthesis protein RibF; Belongs to the ribF family. (310 aa)
EKJ86824.16-pyruvoyl tetrahydropterin synthase. (96 aa)
thyXThymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (307 aa)
EKJ86593.1Polyketide cyclase/dehydrase. (224 aa)
queDQueuosine biosynthesis protein QueD. (124 aa)
EKJ86319.1S-(hydroxymethyl)glutathione synthase. (142 aa)
EKJ86598.1EVE domain protein. (152 aa)
ispEPutative 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (303 aa)
miaAtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (296 aa)
EKJ88238.1Heme oxygenase. (226 aa)
EKJ88408.1NRDE protein. (263 aa)
ubiXPolyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (198 aa)
EKJ85644.1glutamyl-tRNAGlu reductase, N-terminal-like domain protein. (290 aa)
EKJ84867.1Smr domain protein. (91 aa)
mtnDARD/ARD' family protein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (177 aa)
pdhAPyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (328 aa)
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (203 aa)
clpS_3ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. (113 aa)
EKJ85366.1DNA polymerase family B. (752 aa)
EKJ88558.1SET domain protein. (145 aa)
EKJ88785.1DNA polymerase family B. (764 aa)
EKJ88756.1Endonuclease/exonuclease/phosphatase family protein. (260 aa)
Your Current Organism:
Leptospira meyeri
NCBI taxonomy Id: 1193051
Other names: L. meyeri serovar Hardjo str. Went 5, Leptospira meyeri serovar Hardjo str. Went 5
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