STRINGSTRING
CHR53_17285 CHR53_17285 ldh ldh CHR53_21270 CHR53_21270 ilvB ilvB CHR53_25220 CHR53_25220 CHR53_02145 CHR53_02145 CHR53_02275 CHR53_02275 CHR53_03875 CHR53_03875 CHR53_04060 CHR53_04060 CHR53_04725 CHR53_04725 CHR53_04965 CHR53_04965 leuD leuD leuC leuC leuB leuB leuA leuA ilvC ilvC CHR53_05755 CHR53_05755 ilvB-2 ilvB-2 ilvD ilvD CHR53_06310 CHR53_06310 CHR53_08630 CHR53_08630 CHR53_08635 CHR53_08635 pyc pyc CHR53_09920 CHR53_09920 CHR53_09925 CHR53_09925 CHR53_12330 CHR53_12330 ilvA ilvA CHR53_13590 CHR53_13590 CHR53_14260 CHR53_14260
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHR53_17285Unannotated protein. (222 aa)
ldhUnannotated protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (318 aa)
CHR53_21270Unannotated protein. (412 aa)
ilvBUnannotated protein. (567 aa)
CHR53_25220Unannotated protein. (316 aa)
CHR53_02145Unannotated protein; Belongs to the TPP enzyme family. (557 aa)
CHR53_02275Unannotated protein. (362 aa)
CHR53_03875Unannotated protein; Belongs to the TPP enzyme family. (547 aa)
CHR53_04060Unannotated protein. (360 aa)
CHR53_04725Unannotated protein; Belongs to the LDH/MDH superfamily. (324 aa)
CHR53_04965Unannotated protein. (458 aa)
leuDUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (194 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
leuBUnannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (368 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (513 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (343 aa)
CHR53_05755Unannotated protein. (173 aa)
ilvB-2Unannotated protein. (575 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (555 aa)
CHR53_06310Unannotated protein. (372 aa)
CHR53_08630Unannotated protein. (337 aa)
CHR53_08635Unannotated protein. (764 aa)
pycUnannotated protein; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1147 aa)
CHR53_09920Unannotated protein. (578 aa)
CHR53_09925Unannotated protein. (288 aa)
CHR53_12330Unannotated protein; Belongs to the IlvD/Edd family. (735 aa)
ilvAUnannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (421 aa)
CHR53_13590Unannotated protein; Belongs to the TPP enzyme family. (528 aa)
CHR53_14260Unannotated protein; Belongs to the TPP enzyme family. (553 aa)
Your Current Organism:
Bacillus mesonae
NCBI taxonomy Id: 1193713
Other names: B. mesonae, Bacillus mesonae Liu et al. 2014, Bacillus sp. FJAT-13985, CGMCC1.12238, DSM 25968, strain FJAT-13985
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