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dinB dinB CHR53_13150 CHR53_13150 CHR53_12425 CHR53_12425 sat-2 sat-2 galU-3 galU-3 CHR53_11240 CHR53_11240 CHR53_11220 CHR53_11220 ltrA-3 ltrA-3 pnp pnp ribF ribF polC polC CHR53_09685 CHR53_09685 rpoZ rpoZ CHR53_09410 CHR53_09410 coaD coaD CHR53_08870 CHR53_08870 CHR53_07955 CHR53_07955 GCA_001636315_03902 GCA_001636315_03902 GCA_001636315_03901 GCA_001636315_03901 GCA_001636315_03711 GCA_001636315_03711 CHR53_04780 CHR53_04780 dacB-3 dacB-3 galT galT sat sat CHR53_03295 CHR53_03295 selO selO dacB-2 dacB-2 CHR53_01190 CHR53_01190 dacA dacA ltrA-2 ltrA-2 ltrA ltrA rpoA rpoA rpoC rpoC rpoB rpoB ispD ispD disA disA glmU glmU CHR53_00205 CHR53_00205 dnaX dnaX CHR53_00010 CHR53_00010 CHR53_28030 CHR53_28030 mobA mobA rpoE rpoE CHR53_27110 CHR53_27110 CHR53_24580 CHR53_24580 galU-2 galU-2 galU galU GCA_001636315_01616 GCA_001636315_01616 tagD tagD rpoN rpoN CHR53_22840 CHR53_22840 glgC glgC CHR53_21820 CHR53_21820 thiI thiI CHR53_21275 CHR53_21275 polA polA CHR53_21055 CHR53_21055 rph rph GCA_001636315_00953 GCA_001636315_00953 nadD nadD CHR53_20170 CHR53_20170 CHR53_20055 CHR53_20055 dnaG dnaG CHR53_19290 CHR53_19290 cca cca dinG dinG ligD ligD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dinBUnannotated protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (425 aa)
CHR53_13150Unannotated protein. (286 aa)
CHR53_12425Unannotated protein. (214 aa)
sat-2Unannotated protein; Belongs to the sulfate adenylyltransferase family. (382 aa)
galU-3Unannotated protein. (295 aa)
CHR53_11240Unannotated protein. (146 aa)
CHR53_11220Unannotated protein. (194 aa)
ltrA-3Unannotated protein. (625 aa)
pnpUnannotated protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (705 aa)
ribFUnannotated protein; Belongs to the ribF family. (314 aa)
polCUnannotated protein; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1441 aa)
CHR53_09685Unannotated protein. (260 aa)
rpoZUnannotated protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (73 aa)
CHR53_09410Unannotated protein. (291 aa)
coaDUnannotated protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa)
CHR53_08870Unannotated protein; Belongs to the UPF0356 family. (69 aa)
CHR53_07955Unannotated protein. (329 aa)
GCA_001636315_03902Unannotated protein. (412 aa)
GCA_001636315_03901Unannotated protein. (420 aa)
GCA_001636315_03711Unannotated protein. (420 aa)
CHR53_04780Unannotated protein. (190 aa)
dacB-3Unannotated protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (207 aa)
galTUnannotated protein. (495 aa)
satUnannotated protein; Belongs to the sulfate adenylyltransferase family. (379 aa)
CHR53_03295Unannotated protein. (416 aa)
selOUnannotated protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. (486 aa)
dacB-2Unannotated protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (207 aa)
CHR53_01190Unannotated protein. (321 aa)
dacAUnannotated protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (273 aa)
ltrA-2Unannotated protein. (412 aa)
ltrAUnannotated protein. (420 aa)
rpoAUnannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (314 aa)
rpoCUnannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1199 aa)
rpoBUnannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1186 aa)
ispDUnannotated protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (227 aa)
disAUnannotated protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. (357 aa)
glmUUnannotated protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (457 aa)
CHR53_00205Unannotated protein. (335 aa)
dnaXUnannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (563 aa)
CHR53_00010Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] (378 aa)
CHR53_28030Unannotated protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. (659 aa)
mobAUnannotated protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (198 aa)
rpoEUnannotated protein; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (189 aa)
CHR53_27110Unannotated protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (349 aa)
CHR53_24580Unannotated protein; Belongs to the sigma-70 factor family. (239 aa)
galU-2Unannotated protein. (298 aa)
galUUnannotated protein. (292 aa)
GCA_001636315_01616Unannotated protein. (294 aa)
tagDUnannotated protein. (132 aa)
rpoNUnannotated protein. (440 aa)
CHR53_22840Unannotated protein. (259 aa)
glgCUnannotated protein; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (381 aa)
CHR53_21820Unannotated protein. (343 aa)
thiIUnannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (402 aa)
CHR53_21275Unannotated protein. (1121 aa)
polAUnannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (878 aa)
CHR53_21055Unannotated protein. (572 aa)
rphUnannotated protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (271 aa)
GCA_001636315_00953Unannotated protein. (331 aa)
nadDUnannotated protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (189 aa)
CHR53_20170Unannotated protein. (338 aa)
CHR53_20055Unannotated protein. (717 aa)
dnaGUnannotated protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (602 aa)
CHR53_19290Unannotated protein; Belongs to the DNA polymerase type-Y family. (419 aa)
ccaUnannotated protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (399 aa)
dinGUnannotated protein; 3'-5' exonuclease. (942 aa)
ligDUnannotated protein. (614 aa)
Your Current Organism:
Bacillus mesonae
NCBI taxonomy Id: 1193713
Other names: B. mesonae, Bacillus mesonae Liu et al. 2014, Bacillus sp. FJAT-13985, CGMCC1.12238, DSM 25968, strain FJAT-13985
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