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| | CHR53_21580 | Unannotated protein. (143 aa) |
| | CHR53_16230 | Unannotated protein. (214 aa) |
| | CHR53_17375 | Unannotated protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (269 aa) |
| | CHR53_17380 | Unannotated protein; Belongs to the Nudix hydrolase family. (253 aa) |
| | xth | Unannotated protein. (250 aa) |
| | CHR53_17505 | Unannotated protein. (166 aa) |
| | CHR53_17670 | Unannotated protein. (777 aa) |
| | ku | Unannotated protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (290 aa) |
| | ligD | Unannotated protein. (614 aa) |
| | msrA | Unannotated protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (162 aa) |
| | CHR53_18625 | Unannotated protein. (767 aa) |
| | recU | Unannotated protein; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (203 aa) |
| | nth | Unannotated protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (223 aa) |
| | CHR53_18985 | Unannotated protein. (320 aa) |
| | CHR53_19040 | Unannotated protein. (501 aa) |
| | CHR53_19120 | Unannotated protein. (301 aa) |
| | CHR53_19290 | Unannotated protein; Belongs to the DNA polymerase type-Y family. (419 aa) |
| | dinB | Unannotated protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (425 aa) |
| | recN | Unannotated protein; May be involved in recombinational repair of damaged DNA. (562 aa) |
| | CHR53_19565 | Unannotated protein. (224 aa) |
| | CHR53_19905 | Unannotated protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (202 aa) |
| | nfo | Unannotated protein; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (297 aa) |
| | recO | Unannotated protein; Involved in DNA repair and RecF pathway recombination. (250 aa) |
| | CHR53_20190 | Unannotated protein. (213 aa) |
| | recJ | Unannotated protein. (787 aa) |
| | ruvB | Unannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (333 aa) |
| | ruvA | Unannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa) |
| | lon | Unannotated protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (775 aa) |
| | uvrC | Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (591 aa) |
| | mutS2 | Unannotated protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (786 aa) |
| | mutM | Unannotated protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (277 aa) |
| | polA | Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (878 aa) |
| | lexA | Unannotated protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (207 aa) |
| | CHR53_10665 | Unannotated protein. (283 aa) |
| | sbcD | Unannotated protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (382 aa) |
| | CHR53_10785 | Unannotated protein. (193 aa) |
| | CHR53_11340 | Unannotated protein. (196 aa) |
| | CHR53_11370 | Unannotated protein. (158 aa) |
| | CHR53_11615 | Unannotated protein. (483 aa) |
| | CHR53_12560 | Unannotated protein; Belongs to the SOS response-associated peptidase family. (225 aa) |
| | splB | Unannotated protein. (341 aa) |
| | CHR53_13840 | Unannotated protein. (268 aa) |
| | CHR53_14160 | Unannotated protein. (771 aa) |
| | CHR53_14220 | Unannotated protein. (215 aa) |
| | CHR53_14345 | Unannotated protein. (131 aa) |
| | CHR53_14430 | Unannotated protein. (299 aa) |
| | GCA_001636315_05344 | Unannotated protein. (116 aa) |
| | GCA_001636315_05345 | Unannotated protein. (46 aa) |
| | CHR53_14985 | Unannotated protein. (305 aa) |
| | GCA_001636315_05447 | Unannotated protein. (660 aa) |
| | CHR53_15175 | Unannotated protein. (376 aa) |
| | CHR53_15240 | Unannotated protein. (151 aa) |
| | GCA_001636315_05554 | Unannotated protein. (1838 aa) |
| | CHR53_22010 | Unannotated protein. (408 aa) |
| | CHR53_22410 | Unannotated protein. (187 aa) |
| | CHR53_22550 | Unannotated protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (182 aa) |
| | CHR53_23170 | Unannotated protein. (152 aa) |
| | trxB | Unannotated protein. (316 aa) |
| | ppaX | Unannotated protein; Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool. (214 aa) |
| | uvrA | Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (957 aa) |
| | uvrB | Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the [...] (659 aa) |
| | CHR53_23470 | Unannotated protein. (496 aa) |
| | CHR53_23775 | Unannotated protein. (150 aa) |
| | CHR53_25150 | Unannotated protein. (208 aa) |
| | CHR53_25265 | Unannotated protein. (287 aa) |
| | CHR53_25370 | Unannotated protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (210 aa) |
| | GCA_001636315_02181 | Unannotated protein. (129 aa) |
| | CHR53_26725 | Unannotated protein. (104 aa) |
| | CHR53_26820 | Unannotated protein; Belongs to the sigma-70 factor family. (255 aa) |
| | GCA_001636315_02301 | Unannotated protein. (45 aa) |
| | GCA_001636315_02427 | Unannotated protein. (577 aa) |
| | CHR53_27695 | Unannotated protein. (159 aa) |
| | GCA_001636315_02480 | Unannotated protein. (183 aa) |
| | CHR53_27930 | Unannotated protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (162 aa) |
| | CHR53_27940 | Unannotated protein. (190 aa) |
| | CHR53_28060 | Unannotated protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (172 aa) |
| | recF | Unannotated protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (371 aa) |
| | recR | Unannotated protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (198 aa) |
| | mfd | Unannotated protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1180 aa) |
| | CHR53_00345 | Unannotated protein. (92 aa) |
| | radA | Unannotated protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (484 aa) |
| | disA | Unannotated protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. (357 aa) |
| | CHR53_02185 | Unannotated protein. (321 aa) |
| | uvsE | Unannotated protein. (317 aa) |
| | ligA | Unannotated protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (668 aa) |
| | CHR53_02760 | Unannotated protein. (759 aa) |
| | CHR53_02860 | Unannotated protein. (1056 aa) |
| | CHR53_03045 | Unannotated protein. (354 aa) |
| | CHR53_04125 | Unannotated protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (641 aa) |
| | CHR53_04415 | Unannotated protein. (118 aa) |
| | GCA_001636315_03408 | Unannotated protein. (494 aa) |
| | GCA_001636315_03412 | Unannotated protein. (139 aa) |
| | CHR53_04455 | Unannotated protein. (203 aa) |
| | CHR53_04870 | Unannotated protein. (194 aa) |
| | CHR53_04915 | Unannotated protein. (84 aa) |
| | CHR53_05130 | Unannotated protein. (206 aa) |
| | recQ | Unannotated protein. (707 aa) |
| | CHR53_06655 | Unannotated protein. (326 aa) |
| | mutY | Unannotated protein; Adenine glycosylase active on G-A mispairs. (366 aa) |
| | GCA_001636315_03915 | Unannotated protein. (52 aa) |
| | CHR53_07845 | Unannotated protein. (405 aa) |
| | addB | Unannotated protein; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily. (1159 aa) |
| | addA | Unannotated protein; ATP-dependent DNA helicase. (1258 aa) |
| | CHR53_08090 | Unannotated protein; Belongs to the UPF0234 family. (163 aa) |
| | CHR53_08480 | Unannotated protein. (211 aa) |
| | CHR53_08485 | Unannotated protein. (311 aa) |
| | CHR53_08490 | Unannotated protein. (171 aa) |
| | CHR53_08885 | Unannotated protein. (220 aa) |
| | recG | Unannotated protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (682 aa) |
| | CHR53_09885 | Unannotated protein. (100 aa) |
| | CHR53_09895 | Unannotated protein. (133 aa) |
| | GCA_001636315_04415 | Unannotated protein. (112 aa) |
| | mutS | Unannotated protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (873 aa) |
| | mutL | Unannotated protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (647 aa) |
