node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHR53_19840 | CHR53_22370 | GCA_001636315_00821 | GCA_001636315_01368 | Unannotated protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Unannotated protein. | 0.517 |
CHR53_19840 | folD | GCA_001636315_00821 | GCA_001636315_00733 | Unannotated protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.938 |
CHR53_22370 | CHR53_19840 | GCA_001636315_01368 | GCA_001636315_00821 | Unannotated protein. | Unannotated protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.517 |
CHR53_22370 | fhs | GCA_001636315_01368 | GCA_001636315_00526 | Unannotated protein. | Unannotated protein; Belongs to the formate--tetrahydrofolate ligase family. | 0.956 |
CHR53_22370 | folD | GCA_001636315_01368 | GCA_001636315_00733 | Unannotated protein. | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.951 |
CHR53_22370 | glyA | GCA_001636315_01368 | GCA_001636315_00125 | Unannotated protein. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.954 |
CHR53_22370 | glyA-2 | GCA_001636315_01368 | GCA_001636315_02332 | Unannotated protein. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.954 |
fhs | CHR53_22370 | GCA_001636315_00526 | GCA_001636315_01368 | Unannotated protein; Belongs to the formate--tetrahydrofolate ligase family. | Unannotated protein. | 0.956 |
fhs | folD | GCA_001636315_00526 | GCA_001636315_00733 | Unannotated protein; Belongs to the formate--tetrahydrofolate ligase family. | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.994 |
fhs | glyA | GCA_001636315_00526 | GCA_001636315_00125 | Unannotated protein; Belongs to the formate--tetrahydrofolate ligase family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.955 |
fhs | glyA-2 | GCA_001636315_00526 | GCA_001636315_02332 | Unannotated protein; Belongs to the formate--tetrahydrofolate ligase family. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.955 |
folD | CHR53_19840 | GCA_001636315_00733 | GCA_001636315_00821 | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Unannotated protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.938 |
folD | CHR53_22370 | GCA_001636315_00733 | GCA_001636315_01368 | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Unannotated protein. | 0.951 |
folD | fhs | GCA_001636315_00733 | GCA_001636315_00526 | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Unannotated protein; Belongs to the formate--tetrahydrofolate ligase family. | 0.994 |
folD | glyA | GCA_001636315_00733 | GCA_001636315_00125 | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.978 |
folD | glyA-2 | GCA_001636315_00733 | GCA_001636315_02332 | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.978 |
glyA | CHR53_22370 | GCA_001636315_00125 | GCA_001636315_01368 | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Unannotated protein. | 0.954 |
glyA | fhs | GCA_001636315_00125 | GCA_001636315_00526 | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Unannotated protein; Belongs to the formate--tetrahydrofolate ligase family. | 0.955 |
glyA | folD | GCA_001636315_00125 | GCA_001636315_00733 | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.978 |
glyA | glyA-2 | GCA_001636315_00125 | GCA_001636315_02332 | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.902 |