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CHR53_08070 CHR53_08070 GCA_001636315_00017 GCA_001636315_00017 CHR53_16365 CHR53_16365 CHR53_16575 CHR53_16575 thiG thiG thiS thiS thiO thiO CHR53_16595 CHR53_16595 CHR53_16610 CHR53_16610 CHR53_16745 CHR53_16745 CHR53_16965 CHR53_16965 CHR53_16990 CHR53_16990 CHR53_17160 CHR53_17160 CHR53_17275 CHR53_17275 CHR53_18215 CHR53_18215 CHR53_18230 CHR53_18230 metAA metAA bshA bshA bshB1 bshB1 dxs dxs folD folD accC accC lipM lipM mtnN mtnN accA accA accD accD ackA ackA thiI thiI CHR53_21450 CHR53_21450 metK metK CHR53_21725 CHR53_21725 CHR53_21990 CHR53_21990 CHR53_22025 CHR53_22025 CHR53_22105 CHR53_22105 CHR53_22125 CHR53_22125 CHR53_22130 CHR53_22130 metH metH lipA lipA bioA bioA bioD bioD metE metE CHR53_25790 CHR53_25790 CHR53_25960 CHR53_25960 GCA_001636315_02184 GCA_001636315_02184 GCA_001636315_02197 GCA_001636315_02197 CHR53_26600 CHR53_26600 lipL lipL pta pta CHR53_27340 CHR53_27340 thiD thiD CHR53_27415 CHR53_27415 bshB2 bshB2 CHR53_27830 CHR53_27830 cysK cysK cysE cysE CHR53_02885 CHR53_02885 CHR53_02940 CHR53_02940 CHR53_03460 CHR53_03460 cysC cysC sat sat CHR53_03595 CHR53_03595 CHR53_03830 CHR53_03830 CHR53_03865 CHR53_03865 CHR53_03965 CHR53_03965 CHR53_04760 CHR53_04760 CHR53_04930 CHR53_04930 CHR53_04935 CHR53_04935 bioB bioB CHR53_06335 CHR53_06335 CHR53_06345 CHR53_06345 CHR53_06400 CHR53_06400 CHR53_06610 CHR53_06610 CHR53_11480 CHR53_11480 CHR53_11485 CHR53_11485 cysH cysH sat-2 sat-2 cysC-2 cysC-2 CHR53_11705 CHR53_11705 cysI cysI CHR53_11990 CHR53_11990 CHR53_12480 CHR53_12480 CHR53_12590 CHR53_12590 CHR53_12745 CHR53_12745 cysK-2 cysK-2 CHR53_13300 CHR53_13300 CHR53_13370 CHR53_13370 thiC thiC CHR53_13725 CHR53_13725 CHR53_13930 CHR53_13930 CHR53_13940 CHR53_13940 CHR53_14420 CHR53_14420 CHR53_14645 CHR53_14645 CHR53_15840 CHR53_15840 CHR53_09160 CHR53_09160 CHR53_09480 CHR53_09480 asd asd CHR53_10090 CHR53_10090 CHR53_10645 CHR53_10645 thiM thiM thiD-2 thiD-2 thiE thiE CHR53_11465 CHR53_11465 tenA tenA CHR53_11475 CHR53_11475
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHR53_08070Unannotated protein. (342 aa)
GCA_001636315_00017Unannotated protein. (394 aa)
CHR53_16365Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa)
CHR53_16575Unannotated protein. (338 aa)
thiGUnannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa)
thiSUnannotated protein. (67 aa)
thiOUnannotated protein. (369 aa)
CHR53_16595Unannotated protein. (205 aa)
CHR53_16610Unannotated protein. (274 aa)
CHR53_16745Unannotated protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (217 aa)
CHR53_16965Unannotated protein. (271 aa)
CHR53_16990Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (454 aa)
CHR53_17160Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
CHR53_17275Unannotated protein. (389 aa)
CHR53_18215Unannotated protein. (424 aa)
CHR53_18230Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
metAAUnannotated protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (302 aa)
bshAUnannotated protein. (379 aa)
bshB1Unannotated protein. (253 aa)
dxsUnannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (631 aa)
folDUnannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
accCUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
lipMUnannotated protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation. (278 aa)
mtnNUnannotated protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (231 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa)
ackAUnannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
thiIUnannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (402 aa)
CHR53_21450Unannotated protein. (573 aa)
metKUnannotated protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (400 aa)
CHR53_21725Unannotated protein. (259 aa)
CHR53_21990Unannotated protein. (390 aa)
CHR53_22025Unannotated protein. (389 aa)
CHR53_22105Unannotated protein. (429 aa)
CHR53_22125Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
CHR53_22130Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa)
metHUnannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1149 aa)
lipAUnannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (307 aa)
bioAUnannotated protein; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (454 aa)
bioDUnannotated protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (230 aa)
metEUnannotated protein; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (757 aa)
CHR53_25790Unannotated protein. (394 aa)
CHR53_25960Unannotated protein. (383 aa)
GCA_001636315_02184Unannotated protein. (155 aa)
GCA_001636315_02197Unannotated protein. (226 aa)
CHR53_26600Unannotated protein. (395 aa)
lipLUnannotated protein; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (284 aa)
ptaUnannotated protein. (323 aa)
CHR53_27340Unannotated protein. (339 aa)
thiDUnannotated protein. (271 aa)
CHR53_27415Unannotated protein. (115 aa)
bshB2Unannotated protein. (223 aa)
CHR53_27830Unannotated protein. (408 aa)
cysKUnannotated protein; Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa)
cysEUnannotated protein. (222 aa)
CHR53_02885Unannotated protein. (391 aa)
CHR53_02940Unannotated protein. (391 aa)
CHR53_03460Unannotated protein. (385 aa)
cysCUnannotated protein; Catalyzes the synthesis of activated sulfate. (209 aa)
satUnannotated protein; Belongs to the sulfate adenylyltransferase family. (379 aa)
CHR53_03595Unannotated protein. (439 aa)
CHR53_03830Unannotated protein. (365 aa)
CHR53_03865Unannotated protein. (391 aa)
CHR53_03965Unannotated protein. (834 aa)
CHR53_04760Unannotated protein. (435 aa)
CHR53_04930Unannotated protein. (395 aa)
CHR53_04935Unannotated protein. (395 aa)
bioBUnannotated protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (337 aa)
CHR53_06335Unannotated protein. (286 aa)
CHR53_06345Unannotated protein. (392 aa)
CHR53_06400Unannotated protein. (389 aa)
CHR53_06610Unannotated protein. (409 aa)
CHR53_11480Unannotated protein. (257 aa)
CHR53_11485Unannotated protein. (332 aa)
cysHUnannotated protein; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (238 aa)
sat-2Unannotated protein; Belongs to the sulfate adenylyltransferase family. (382 aa)
cysC-2Unannotated protein; Catalyzes the synthesis of activated sulfate. (199 aa)
CHR53_11705Unannotated protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (601 aa)
cysIUnannotated protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (573 aa)
CHR53_11990Unannotated protein. (411 aa)
CHR53_12480Unannotated protein. (261 aa)
CHR53_12590Unannotated protein. (136 aa)
CHR53_12745Unannotated protein. (396 aa)
cysK-2Unannotated protein; Belongs to the cysteine synthase/cystathionine beta- synthase family. (307 aa)
CHR53_13300Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
CHR53_13370Unannotated protein. (273 aa)
thiCUnannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (590 aa)
CHR53_13725Unannotated protein. (140 aa)
CHR53_13930Unannotated protein. (438 aa)
CHR53_13940Unannotated protein. (329 aa)
CHR53_14420Unannotated protein. (127 aa)
CHR53_14645Unannotated protein. (128 aa)
CHR53_15840Unannotated protein. (259 aa)
CHR53_09160Unannotated protein. (445 aa)
CHR53_09480Unannotated protein. (215 aa)
asdUnannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (351 aa)
CHR53_10090Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa)
CHR53_10645Unannotated protein. (255 aa)
thiMUnannotated protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (269 aa)
thiD-2Unannotated protein. (272 aa)
thiEUnannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (215 aa)
CHR53_11465Unannotated protein. (427 aa)
tenAUnannotated protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (223 aa)
CHR53_11475Unannotated protein. (262 aa)
Your Current Organism:
Bacillus mesonae
NCBI taxonomy Id: 1193713
Other names: B. mesonae, Bacillus mesonae Liu et al. 2014, Bacillus sp. FJAT-13985, CGMCC1.12238, DSM 25968, strain FJAT-13985
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