STRINGSTRING
CHR53_14180 CHR53_14180 CHR53_15225 CHR53_15225 GCA_001636315_05554 GCA_001636315_05554 CHR53_15760 CHR53_15760 topB topB CHR53_17670 CHR53_17670 racA racA CHR53_18460 CHR53_18460 CHR53_18625 CHR53_18625 CHR53_18880 CHR53_18880 CHR53_19040 CHR53_19040 CHR53_19235 CHR53_19235 CHR53_19725 CHR53_19725 GCA_001636315_00796 GCA_001636315_00796 dnaG dnaG recD2 recD2 ruvB ruvB ruvA ruvA CHR53_21400 CHR53_21400 CHR53_23470 CHR53_23470 CHR53_23710 CHR53_23710 CHR53_26675 CHR53_26675 CHR53_26680 CHR53_26680 CHR53_27685 CHR53_27685 CHR53_28020 CHR53_28020 gyrB gyrB gyrA gyrA CHR53_00275 CHR53_00275 mfd mfd CHR53_01505 CHR53_01505 pcrA pcrA GCA_001636315_03411 GCA_001636315_03411 CHR53_04590 CHR53_04590 CHR53_04840 CHR53_04840 recQ recQ CHR53_07750 CHR53_07750 addB addB addA addA CHR53_08440 CHR53_08440 CHR53_08610 CHR53_08610 priA priA recG recG smc smc topA topA CHR53_12015 CHR53_12015 parE parE parC parC CHR53_13280 CHR53_13280 CHR53_13550 CHR53_13550 CHR53_13840 CHR53_13840 CHR53_14120 CHR53_14120 CHR53_14160 CHR53_14160
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHR53_14180Unannotated protein; Belongs to the bacterial histone-like protein family. (89 aa)
CHR53_15225Unannotated protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (92 aa)
GCA_001636315_05554Unannotated protein. (1838 aa)
CHR53_15760Unannotated protein. (420 aa)
topBUnannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (729 aa)
CHR53_17670Unannotated protein. (777 aa)
racAUnannotated protein; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family. (173 aa)
CHR53_18460Unannotated protein. (722 aa)
CHR53_18625Unannotated protein. (767 aa)
CHR53_18880Unannotated protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
CHR53_19040Unannotated protein. (501 aa)
CHR53_19235Unannotated protein. (388 aa)
CHR53_19725Unannotated protein. (562 aa)
GCA_001636315_00796Unannotated protein. (626 aa)
dnaGUnannotated protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (602 aa)
recD2Unannotated protein; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (801 aa)
ruvBUnannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (333 aa)
ruvAUnannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa)
CHR53_21400Unannotated protein. (66 aa)
CHR53_23470Unannotated protein. (496 aa)
CHR53_23710Unannotated protein. (516 aa)
CHR53_26675Unannotated protein. (543 aa)
CHR53_26680Unannotated protein. (1001 aa)
CHR53_27685Unannotated protein. (248 aa)
CHR53_28020Unannotated protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (454 aa)
gyrBUnannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (645 aa)
gyrAUnannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (851 aa)
CHR53_00275Unannotated protein. (60 aa)
mfdUnannotated protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1180 aa)
CHR53_01505Unannotated protein. (84 aa)
pcrAUnannotated protein. (752 aa)
GCA_001636315_03411Unannotated protein. (615 aa)
CHR53_04590Unannotated protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (92 aa)
CHR53_04840Unannotated protein. (1057 aa)
recQUnannotated protein. (707 aa)
CHR53_07750Unannotated protein. (67 aa)
addBUnannotated protein; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily. (1159 aa)
addAUnannotated protein; ATP-dependent DNA helicase. (1258 aa)
CHR53_08440Unannotated protein. (766 aa)
CHR53_08610Unannotated protein. (66 aa)
priAUnannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (803 aa)
recGUnannotated protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (682 aa)
smcUnannotated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1188 aa)
topAUnannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (692 aa)
CHR53_12015Unannotated protein. (635 aa)
parEUnannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. (666 aa)
parCUnannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily. (814 aa)
CHR53_13280Unannotated protein. (758 aa)
CHR53_13550Unannotated protein. (62 aa)
CHR53_13840Unannotated protein. (268 aa)
CHR53_14120Unannotated protein. (1487 aa)
CHR53_14160Unannotated protein. (771 aa)
Your Current Organism:
Bacillus mesonae
NCBI taxonomy Id: 1193713
Other names: B. mesonae, Bacillus mesonae Liu et al. 2014, Bacillus sp. FJAT-13985, CGMCC1.12238, DSM 25968, strain FJAT-13985
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.