STRINGSTRING
CHR53_05800 CHR53_05800 CHR53_17110 CHR53_17110 dacB dacB racA racA gpsB gpsB scpB scpB scpA scpA xerD xerD CHR53_20380 CHR53_20380 minD minD minC minC CHR53_20770 CHR53_20770 engB engB tig tig CHR53_21065 CHR53_21065 ezrA ezrA murC murC CHR53_21600 CHR53_21600 CHR53_21620 CHR53_21620 CHR53_22835 CHR53_22835 whiA whiA CHR53_23375 CHR53_23375 CHR53_23390 CHR53_23390 ftsE ftsE CHR53_23820 CHR53_23820 GCA_001636315_02159 GCA_001636315_02159 murA murA murA-2 murA-2 noc noc spoVG spoVG CHR53_00360 CHR53_00360 CHR53_01540 CHR53_01540 murF murF essC essC CHR53_02365 CHR53_02365 CHR53_03080 CHR53_03080 CHR53_03590 CHR53_03590 CHR53_04445 CHR53_04445 CHR53_04850 CHR53_04850 CHR53_05070 CHR53_05070 CHR53_09015 CHR53_09015 ftsL ftsL murE murE mraY mraY murD murD CHR53_09235 CHR53_09235 murG murG murB murB divIB divIB CHR53_09255 CHR53_09255 CHR53_09260 CHR53_09260 ftsA ftsA ftsZ ftsZ sepF sepF CHR53_09315 CHR53_09315 CHR53_09325 CHR53_09325 CHR53_09815 CHR53_09815 CHR53_09915 CHR53_09915 CHR53_13020 CHR53_13020 ftsZ-2 ftsZ-2 CHR53_13625 CHR53_13625 CHR53_13985 CHR53_13985 CHR53_15265 CHR53_15265 GCA_001636315_05491 GCA_001636315_05491 GCA_001636315_05505 GCA_001636315_05505 CHR53_15250 CHR53_15250 GCA_001636315_05539 GCA_001636315_05539 GCA_001636315_05549 GCA_001636315_05549
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHR53_05800Unannotated protein. (95 aa)
CHR53_17110Unannotated protein. (344 aa)
dacBUnannotated protein. (492 aa)
racAUnannotated protein; Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure; Belongs to the RacA family. (173 aa)
gpsBUnannotated protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. (100 aa)
scpBUnannotated protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (206 aa)
scpAUnannotated protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (256 aa)
xerDUnannotated protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (297 aa)
CHR53_20380Unannotated protein. (583 aa)
minDUnannotated protein. (267 aa)
minCUnannotated protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (227 aa)
CHR53_20770Unannotated protein. (330 aa)
engBUnannotated protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (193 aa)
tigUnannotated protein; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (425 aa)
CHR53_21065Unannotated protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (87 aa)
ezrAUnannotated protein; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (562 aa)
murCUnannotated protein; Cell wall formation; Belongs to the MurCDEF family. (432 aa)
CHR53_21600Unannotated protein. (418 aa)
CHR53_21620Unannotated protein. (543 aa)
CHR53_22835Unannotated protein; Belongs to the SEDS family. (389 aa)
whiAUnannotated protein; Involved in cell division and chromosome segregation. (316 aa)
CHR53_23375Unannotated protein. (396 aa)
CHR53_23390Unannotated protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (308 aa)
ftsEUnannotated protein; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)
CHR53_23820Unannotated protein. (404 aa)
GCA_001636315_02159Unannotated protein. (321 aa)
murAUnannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (436 aa)
murA-2Unannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (428 aa)
nocUnannotated protein; Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage. Belongs to the ParB family. (285 aa)
spoVGUnannotated protein; Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation. (96 aa)
CHR53_00360Unannotated protein. (127 aa)
CHR53_01540Unannotated protein; Belongs to the SEDS family. (395 aa)
murFUnannotated protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (459 aa)
essCUnannotated protein. (1512 aa)
CHR53_02365Unannotated protein. (410 aa)
CHR53_03080Unannotated protein. (370 aa)
CHR53_03590Unannotated protein. (461 aa)
CHR53_04445Unannotated protein. (283 aa)
CHR53_04850Unannotated protein. (93 aa)
CHR53_05070Unannotated protein; Belongs to the SEDS family. (425 aa)
CHR53_09015Unannotated protein; Belongs to the SEDS family. (401 aa)
ftsLUnannotated protein; Essential cell division protein; Belongs to the FtsL family. (120 aa)
murEUnannotated protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (486 aa)
mraYUnannotated protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (324 aa)
murDUnannotated protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (450 aa)
CHR53_09235Unannotated protein; Belongs to the SEDS family. (366 aa)
murGUnannotated protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (367 aa)
murBUnannotated protein; Cell wall formation. (302 aa)
divIBUnannotated protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (256 aa)
CHR53_09255Unannotated protein. (231 aa)
CHR53_09260Unannotated protein. (243 aa)
ftsAUnannotated protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (430 aa)
ftsZUnannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (382 aa)
sepFUnannotated protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (149 aa)
CHR53_09315Unannotated protein. (87 aa)
CHR53_09325Unannotated protein. (171 aa)
CHR53_09815Unannotated protein; Belongs to the FtsK/SpoIIIE/SftA family. (766 aa)
CHR53_09915Unannotated protein. (86 aa)
CHR53_13020Unannotated protein; Belongs to the 'phage' integrase family. (360 aa)
ftsZ-2Unannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (442 aa)
CHR53_13625Unannotated protein. (300 aa)
CHR53_13985Unannotated protein. (944 aa)
CHR53_15265Unannotated protein; Belongs to the 'phage' integrase family. (279 aa)
GCA_001636315_05491Unannotated protein. (248 aa)
GCA_001636315_05505Unannotated protein. (141 aa)
CHR53_15250Unannotated protein. (247 aa)
GCA_001636315_05539Unannotated protein. (283 aa)
GCA_001636315_05549Unannotated protein. (1565 aa)
Your Current Organism:
Bacillus mesonae
NCBI taxonomy Id: 1193713
Other names: B. mesonae, Bacillus mesonae Liu et al. 2014, Bacillus sp. FJAT-13985, CGMCC1.12238, DSM 25968, strain FJAT-13985
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