(24 nodes) Thiamin diphosphate-binding fold network (Bacillus mesonae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	xsc	Unannotated protein; Belongs to the TPP enzyme family. (589 aa)
	CHR53_17285	Unannotated protein. (222 aa)
	odhA	Unannotated protein; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (941 aa)
	CHR53_19410	Unannotated protein. (327 aa)
	CHR53_19415	Unannotated protein. (330 aa)
	dxs	Unannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (631 aa)
	CHR53_20475	Unannotated protein. (338 aa)
	pdhA	Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (366 aa)
	menD	Unannotated protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (583 aa)
	ilvB	Unannotated protein. (567 aa)
	CHR53_26135	Unannotated protein; Belongs to the TPP enzyme family. (544 aa)
	CHR53_02145	Unannotated protein; Belongs to the TPP enzyme family. (557 aa)
	CHR53_03875	Unannotated protein; Belongs to the TPP enzyme family. (547 aa)
	ilvB-2	Unannotated protein. (575 aa)
	CHR53_08635	Unannotated protein. (764 aa)
	pdhA-2	Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa)
	CHR53_08895	Unannotated protein. (325 aa)
	CHR53_09920	Unannotated protein. (578 aa)
	CHR53_09925	Unannotated protein. (288 aa)
	tkt	Unannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa)
	CHR53_13590	Unannotated protein; Belongs to the TPP enzyme family. (528 aa)
	CHR53_13935	Unannotated protein. (326 aa)
	CHR53_13940	Unannotated protein. (329 aa)
	CHR53_14260	Unannotated protein; Belongs to the TPP enzyme family. (553 aa)

Your Current Organism:

Bacillus mesonae

NCBI taxonomy Id: 1193713
Other names: B. mesonae, Bacillus mesonae Liu et al. 2014, Bacillus sp. FJAT-13985, CGMCC1.12238, DSM 25968, strain FJAT-13985

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHR53_02145	CHR53_08635	GCA_001636315_02952	GCA_001636315_04168	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.927
CHR53_02145	CHR53_08895	GCA_001636315_02952	GCA_001636315_04219	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.632
CHR53_02145	CHR53_09920	GCA_001636315_02952	GCA_001636315_04419	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.927
CHR53_02145	CHR53_09925	GCA_001636315_02952	GCA_001636315_04420	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.908
CHR53_02145	CHR53_17285	GCA_001636315_02952	GCA_001636315_00289	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.855
CHR53_02145	CHR53_20475	GCA_001636315_02952	GCA_001636315_00976	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.632
CHR53_02145	pdhA	GCA_001636315_02952	GCA_001636315_00977	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.631
CHR53_02145	pdhA-2	GCA_001636315_02952	GCA_001636315_04218	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.631
CHR53_03875	CHR53_08635	GCA_001636315_03292	GCA_001636315_04168	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.927
CHR53_03875	CHR53_08895	GCA_001636315_03292	GCA_001636315_04219	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.632
CHR53_03875	CHR53_09920	GCA_001636315_03292	GCA_001636315_04419	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.927
CHR53_03875	CHR53_09925	GCA_001636315_03292	GCA_001636315_04420	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.908
CHR53_03875	CHR53_17285	GCA_001636315_03292	GCA_001636315_00289	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.852
CHR53_03875	CHR53_20475	GCA_001636315_03292	GCA_001636315_00976	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein.	0.632
CHR53_03875	pdhA	GCA_001636315_03292	GCA_001636315_00977	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.631
CHR53_03875	pdhA-2	GCA_001636315_03292	GCA_001636315_04218	Unannotated protein; Belongs to the TPP enzyme family.	Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.631
CHR53_08635	CHR53_02145	GCA_001636315_04168	GCA_001636315_02952	Unannotated protein.	Unannotated protein; Belongs to the TPP enzyme family.	0.927
CHR53_08635	CHR53_03875	GCA_001636315_04168	GCA_001636315_03292	Unannotated protein.	Unannotated protein; Belongs to the TPP enzyme family.	0.927
CHR53_08635	CHR53_08895	GCA_001636315_04168	GCA_001636315_04219	Unannotated protein.	Unannotated protein.	0.925
CHR53_08635	CHR53_09920	GCA_001636315_04168	GCA_001636315_04419	Unannotated protein.	Unannotated protein.	0.999