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A361_00445 A361_00445 A361_00625 A361_00625 A361_01030 A361_01030 A361_02195 A361_02195 A361_02835 A361_02835 A361_04040 A361_04040 A361_06045 A361_06045 A361_06425 A361_06425 argC argC argJ argJ argB argB argD argD A361_08390 A361_08390 A361_08440 A361_08440 A361_08620 A361_08620 dapH dapH A361_08740 A361_08740 asd asd A361_09990 A361_09990 dapA dapA A361_11620 A361_11620 arcA arcA A361_12440 A361_12440 A361_12620 A361_12620 A361_13075 A361_13075 A361_13080 A361_13080 A361_13085 A361_13085 A361_13090 A361_13090 A361_13160 A361_13160 A361_14600 A361_14600 A361_15525 A361_15525 A361_15535 A361_15535 eutB eutB dapF dapF A361_18690 A361_18690 ilvA ilvA A361_18895 A361_18895 metAA metAA dapB dapB lysA lysA argR argR A361_21955 A361_21955 argH argH argG argG A361_22415 A361_22415 A361_22420 A361_22420 A361_22610 A361_22610 A361_22620 A361_22620 metK metK rocD rocD A361_23485 A361_23485 thrB thrB A361_23750 A361_23750 A361_23755 A361_23755 A361_23915 A361_23915 dapA-2 dapA-2 argH-2 argH-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A361_00445Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa)
A361_00625Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
A361_01030Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (301 aa)
A361_02195Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (454 aa)
A361_02835Cysteine synthase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
A361_04040Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (310 aa)
A361_06045Succinyl-diaminopimelate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
A361_06425Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (343 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (257 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (385 aa)
A361_08390Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
A361_08440LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
A361_08620Catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
dapH2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (236 aa)
A361_08740N-acetyldiaminopimelate deacetylase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (374 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (349 aa)
A361_09990Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (414 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (288 aa)
A361_11620Nitric oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. (361 aa)
arcAArginine deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
A361_12440Acetylornithine deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
A361_12620Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
A361_13075Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
A361_13080Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
A361_13085Bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. (616 aa)
A361_13090Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1148 aa)
A361_13160Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
A361_14600LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
A361_15525Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
A361_15535Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
eutBHydroxyectoine utilization dehydratase EutB; Catalyzes the formation of 2-oxobutanoate from L-threonine; involved in ectoine utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (327 aa)
A361_18690Acetylornithine deacetylase; Catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (422 aa)
A361_18895LL-diaminopimelate aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (302 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (439 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (149 aa)
A361_21955Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (409 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
argGArgininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (402 aa)
A361_22415Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
A361_22420Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
A361_22610Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)
A361_22620Dipeptidase PepV; Divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (397 aa)
rocDOrnithine--oxo-acid transaminase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (399 aa)
A361_23485Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (311 aa)
A361_23750Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa)
A361_23755Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
A361_23915O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
dapA-2Dihydrodipicolinate synthase family protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa)
argH-2Argininosuccinate lyase; Catalyzes the formation of arginine and fumarate from arginosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
Your Current Organism:
Bacillus oceanisediminis
NCBI taxonomy Id: 1196031
Other names: B. oceanisediminis 2691, Bacillus oceanisediminis 2691
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