(15 nodes) Nicotinamide nucleotide metabolic process, and Ribosome assembly network (Bacillus oceanisediminis)

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	ppnK	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (264 aa)
	cobB	NAD-dependent protein deacylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (237 aa)
	A361_11045	Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
	A361_12295	Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
	nadE	NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (273 aa)
	A361_12990	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (485 aa)
	A361_21260	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
	rsfS	Ribosome silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (118 aa)
	A361_21270	Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
	nadD	Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (189 aa)
	A361_21280	RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
	A361_21290	Ribosome biogenesis GTPase YqeH; In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
	A361_21295	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
	ppnK-2	NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (266 aa)
	A361_22520	Nicotinate phosphoribosyltransferase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAPRTase family. (365 aa)

Your Current Organism:

Bacillus oceanisediminis

NCBI taxonomy Id: 1196031
Other names: B. oceanisediminis 2691, Bacillus oceanisediminis 2691

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A361_11045	A361_12990	A361_11045	A361_12990	Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.950
A361_11045	A361_22520	A361_11045	A361_22520	Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nicotinate phosphoribosyltransferase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAPRTase family.	0.950
A361_11045	cobB	A361_11045	A361_08215	Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD-dependent protein deacylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.996
A361_11045	nadD	A361_11045	A361_21275	Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.939
A361_11045	nadE	A361_11045	A361_12985	Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.951
A361_11045	ppnK	A361_11045	A361_07625	Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.934
A361_11045	ppnK-2	A361_11045	A361_22360	Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.934
A361_12295	A361_12990	A361_12295	A361_12990	Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.615
A361_12295	A361_22520	A361_12295	A361_22520	Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nicotinate phosphoribosyltransferase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAPRTase family.	0.615
A361_12990	A361_11045	A361_12990	A361_11045	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.950
A361_12990	A361_12295	A361_12990	A361_12295	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.615
A361_12990	A361_22520	A361_12990	A361_22520	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Nicotinate phosphoribosyltransferase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAPRTase family.	0.900
A361_12990	nadD	A361_12990	A361_21275	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.930
A361_12990	nadE	A361_12990	A361_12985	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.855
A361_21260	A361_21270	A361_21260	A361_21270	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.835
A361_21260	A361_21280	A361_21260	A361_21280	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
A361_21260	A361_21290	A361_21260	A361_21290	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribosome biogenesis GTPase YqeH; In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.658
A361_21260	A361_21295	A361_21260	A361_21295	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.603
A361_21260	nadD	A361_21260	A361_21275	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.819
A361_21260	rsfS	A361_21260	A361_21265	Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribosome silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.812