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A361_01125 A361_01125 A361_01130 A361_01130 A361_01135 A361_01135 A361_01140 A361_01140 A361_01285 A361_01285 btuC btuC A361_01295 A361_01295 cobD cobD A361_01305 A361_01305 A361_01310 A361_01310 cobQ cobQ cobS cobS A361_01325 A361_01325 A361_01330 A361_01330 A361_01335 A361_01335 A361_01340 A361_01340 A361_01345 A361_01345 A361_01350 A361_01350 A361_02310 A361_02310 A361_02315 A361_02315 A361_02320 A361_02320 A361_02325 A361_02325 A361_02340 A361_02340 A361_02345 A361_02345 A361_02350 A361_02350 A361_02355 A361_02355 A361_02360 A361_02360 A361_02810 A361_02810 A361_02815 A361_02815 A361_02820 A361_02820 A361_04670 A361_04670 A361_05835 A361_05835 hemL hemL A361_06200 A361_06200 A361_06455 A361_06455 A361_06480 A361_06480 A361_06485 A361_06485 A361_06880 A361_06880 hemE hemE hemH hemH A361_07055 A361_07055 A361_07360 A361_07360 A361_11570 A361_11570 A361_11845 A361_11845 A361_11850 A361_11850 A361_11855 A361_11855 cysC cysC sat sat A361_13640 A361_13640 A361_13645 A361_13645 A361_13650 A361_13650 cysC-2 cysC-2 sat-2 sat-2 A361_13665 A361_13665 cysH cysH A361_14630 A361_14630 A361_14640 A361_14640 A361_15060 A361_15060 A361_15065 A361_15065 A361_15070 A361_15070 A361_15075 A361_15075 A361_15080 A361_15080 A361_15085 A361_15085 A361_15090 A361_15090 A361_15095 A361_15095 A361_15100 A361_15100 A361_15105 A361_15105 cbiA cbiA A361_15115 A361_15115 A361_15120 A361_15120 A361_15125 A361_15125 A361_15130 A361_15130 cbiD cbiD A361_15140 A361_15140 A361_15145 A361_15145 A361_15150 A361_15150 cysI cysI A361_17530 A361_17530 A361_17565 A361_17565 A361_19055 A361_19055 A361_20900 A361_20900 pstB pstB A361_20910 A361_20910 A361_20915 A361_20915 A361_20920 A361_20920 A361_20940 A361_20940 A361_20945 A361_20945 hemL-2 hemL-2 A361_21770 A361_21770 A361_21775 A361_21775 hemC hemC hemA hemA A361_22255 A361_22255 A361_23670 A361_23670 A361_23675 A361_23675 A361_23680 A361_23680 A361_23685 A361_23685 A361_23980 A361_23980 A361_23985 A361_23985 A361_23990 A361_23990 A361_23995 A361_23995 A361_24000 A361_24000 A361_24005 A361_24005 A361_26270 A361_26270
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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A361_01125Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (317 aa)
A361_01130Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (317 aa)
A361_01135Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
A361_01140Ferrichrome ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
A361_01285Iron ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
btuCABC transporter permease; Required for transport of corrinoids such as cobalamin; functions as a complex of BtuCDF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (350 aa)
A361_01295ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (321 aa)
A361_01305Threonine-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
A361_01310Cobinamide kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (507 aa)
cobSadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (263 aa)
A361_01325Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
A361_01330Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
A361_01335Cobalamin adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (195 aa)
A361_01340Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
A361_01345ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
A361_01350Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (206 aa)
A361_02310Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (335 aa)
A361_02315Iron ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (336 aa)
A361_02320ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
A361_02325Iron-enterobactin transporter ATP-binding protein; With FepBDE is involved in the transport of ferric enterobactin; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
A361_02340Antibiotic biosynthesis monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
A361_02345Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (343 aa)
A361_02350Ferrichrome ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (344 aa)
A361_02355Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
A361_02360ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
A361_02810Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
A361_02815NAD(P)H nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
A361_02820Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
A361_04670ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
A361_05835Choloylglycine hydrolase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (461 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
A361_06200cob(I)yrinic acid a c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (185 aa)
A361_06455Sodium:dicarboxylate symporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (462 aa)
A361_06480Inorganic phosphate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
A361_06485Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
A361_06880Coproporphyrinogen III oxidase; Catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (348 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (310 aa)
A361_07055Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (479 aa)
A361_07360Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
A361_11570uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
A361_11845Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
A361_11850Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
A361_11855Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
cysCAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (197 aa)
satATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
A361_13640Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
A361_13645Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
A361_13650uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
cysC-2Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (199 aa)
sat-2ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
A361_13665Sulfate permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (238 aa)
A361_14630Flavodoxin; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
A361_14640Hypothetical protein; Frameshifted; incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
A361_15060Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
A361_15065Sirohydrochlorin cobaltochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
A361_15070Iron ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
A361_15075Iron ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
A361_15080ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (346 aa)
A361_15085Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
A361_15090cob(I)yrinic acid a,c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
A361_15095Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
A361_15100uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
A361_15105Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (461 aa)
A361_15115Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
A361_15120Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (260 aa)
A361_15125Precorrin-2 C(20)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (234 aa)
A361_15130Cobalamin biosynthesis protein CbiE; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
cbiDcobalt-precorrin-5B (C(1))-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (378 aa)
A361_15140precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
A361_15145Precorrin-6x reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
A361_15150cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
cysISulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (573 aa)
A361_17530Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (603 aa)
A361_17565Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
A361_190553-mercaptopyruvate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
A361_20900Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake. (220 aa)
pstBPhosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (275 aa)
A361_20910Phosphate ABC transporter, permease protein PstA; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
A361_20915Phosphate ABC transporter permease subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (318 aa)
A361_20920Phosphate ABC transporter phosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
A361_20940Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
A361_20945Sodium-dependent phosphate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
hemL-2Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
A361_21770Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (326 aa)
A361_21775uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (260 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (449 aa)
A361_22255Oligoribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
A361_23670Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
A361_23675Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
A361_23680Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
A361_23685Cobalamin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
A361_23980Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
A361_23985Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
A361_23990ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
A361_23995Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (351 aa)
A361_24000Iron ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (333 aa)
A361_24005Iron siderophore-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
A361_26270Heme-dependent peroxidase; May function as heme-dependent peroxidase. (247 aa)
Your Current Organism:
Bacillus oceanisediminis
NCBI taxonomy Id: 1196031
Other names: B. oceanisediminis 2691, Bacillus oceanisediminis 2691
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