(15 nodes) Cobalamin metabolic process, and Siroheme metabolic process network (Bacillus oceanisediminis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A361_13640	Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
	A361_13645	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
	A361_13650	uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
	A361_15065	Sirohydrochlorin cobaltochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
	A361_15095	Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
	A361_15105	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
	cbiA	Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (461 aa)
	A361_15115	Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
	A361_15120	Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (260 aa)
	A361_15125	Precorrin-2 C(20)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (234 aa)
	A361_15130	Cobalamin biosynthesis protein CbiE; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
	cbiD	cobalt-precorrin-5B (C(1))-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (378 aa)
	A361_15140	precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	A361_15145	Precorrin-6x reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
	A361_15150	cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)

Your Current Organism:

Bacillus oceanisediminis

NCBI taxonomy Id: 1196031
Other names: B. oceanisediminis 2691, Bacillus oceanisediminis 2691

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A361_13640	A361_13645	A361_13640	A361_13645	Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
A361_13640	A361_13650	A361_13640	A361_13650	Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
A361_13640	A361_15065	A361_13640	A361_15065	Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sirohydrochlorin cobaltochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.967
A361_13640	A361_15105	A361_13640	A361_15105	Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
A361_13640	A361_15120	A361_13640	A361_15120	Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.	Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	0.701
A361_13640	A361_15125	A361_13640	A361_15125	Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.	Precorrin-2 C(20)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	0.933
A361_13640	A361_15130	A361_13640	A361_15130	Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cobalamin biosynthesis protein CbiE; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.530
A361_13640	A361_15150	A361_13640	A361_15150	Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.	cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.685
A361_13645	A361_13640	A361_13645	A361_13640	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
A361_13645	A361_13650	A361_13645	A361_13650	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.866
A361_13645	A361_15065	A361_13645	A361_15065	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sirohydrochlorin cobaltochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
A361_13645	A361_15105	A361_13645	A361_15105	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.964
A361_13645	A361_15115	A361_13645	A361_15115	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.792
A361_13645	A361_15120	A361_13645	A361_15120	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	0.709
A361_13645	A361_15125	A361_13645	A361_15125	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Precorrin-2 C(20)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.	0.788
A361_13645	A361_15130	A361_13645	A361_15130	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cobalamin biosynthesis protein CbiE; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.852
A361_13645	A361_15140	A361_13645	A361_15140	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	precorrin-8X methylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.964
A361_13645	A361_15145	A361_13645	A361_15145	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Precorrin-6x reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.660
A361_13645	A361_15150	A361_13645	A361_15150	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.882
A361_13645	cbiA	A361_13645	A361_15110	Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.	0.644